It's long been known that replacing the blood of an elderly person with that of a youth will make the codger feel like a million bucks. It really does work and, if I were a wealthy old guy, I would definitely have a stable of donors on hand and get weekly treatments.
Studies: Blood from young mice reverses aging in old mice
31–40 of 54 posts
Re: Studies: Blood from young mice reverses aging in old mice
#32"Yes, yes," agreed Hardy. "Naturally---but what is the basic process?" "It consists largely in replacing the entire blood tissue in an old person with new, young blood..."
Re: Studies: Blood from young mice reverses aging in old mice
#33Earlier quoted context omitted.
Please don't post substanceless one-liners here. i.e. don't make jokes. I've wondered about this because I've done the same thing and gotten downvoted. There's nothing about not making jokes in the guidelines. Personally I like a little humor mixed with my HN. Is there some unspoken guideline that HN is supposed to be humorless? And on a semi-serious note, isn't mildly interesting that one of the most common cultural…
scott_s made an insightful comment about this recently: https://news.ycombinator.com/item?id=7609289 . HN isn't against humor per se. Personally, when I read Reddit, I'm in awe of how good the best jokes are. The problem is that you can't have everything; with a culture of humor comes a flood of lame humor. HN's tradeoff is to optimize for signal-noise ratio, so that stuff tends to get hammered. There are other place…
Re: Studies: Blood from young mice reverses aging in old mice
#34It's been known for centuries that drinking blood of young... Oh wait, that was a movie :)
Re: Studies: Blood from young mice reverses aging in old mice
#35It's been known for centuries that drinking blood of young... Oh wait, that was a movie :)
Re: Studies: Blood from young mice reverses aging in old mice
#36Earlier quoted context omitted.
Please don't post substanceless one-liners here. The second one sounds more serious, but "wow time to start talking about the ethics of immortality" doesn't engage with anything in this article; it's simply an immediate leap to something generic and obvious. That is not what HN discussions need.
Please don't post substanceless one-liners here. i.e. don't make jokes. I've wondered about this because I've done the same thing and gotten downvoted. There's nothing about not making jokes in the guidelines. Personally I like a little humor mixed with my HN. Is there some unspoken guideline that HN is supposed to be humorless? And on a semi-serious note, isn't mildly interesting that one of the most common cultural…
Re: Studies: Blood from young mice reverses aging in old mice
#37Earlier quoted context omitted.
Aging is more than just accumulated dammage, menopause is a clear counter example to this idea. However, dammage does accumulate so like most complex systems there are no simple answers.
Isn't menopoause caused by running out of eggs? Actually this is the same mechanism as reported in this story - a lack of stem cells. The interesting thing about this is the stem cells can be reactivated.
Further, all the eggs a woman will ever have are created while she is developing in her own mother. This is totally distinct from stem cells, many of which are able to generate new stem cells throughout our lives, albeit at an ever-decreasing rate.
[1] http://www.mayoclinic.org/diseases-conditions/menopause/basi...
Re: Studies: Blood from young mice reverses aging in old mice
#38Earlier quoted context omitted.
Scientists do a lot of grotesque things to mice, rats and insects all the time. We have to test stuff on someone, and humans are not really acceptable, even with consent.
I agree with you.. but.. going to argue the other way anyway ;) Isn't a consenting subject better than a forced subject? The mice had no say, but a human does..
There are other reasons why test animals are not that useful, mostly because they aren't human, and what works in them might not work on people, and what doesn't work in them won't be tested on people.
Over time animal testing has been decreasing and will continue to decrease while cell cultures become easier to create and closer to the cell structures that need to be tested, but for now they are needed in many fields of science.
Re: Studies: Blood from young mice reverses aging in old mice
#39Earlier quoted context omitted.
Aging is more than just accumulated dammage, menopause is a clear counter example to this idea. However, dammage does accumulate so like most complex systems there are no simple answers.
Menopause is not a clear counter example. For all intents and purposes it is a symptom of biological aging and thus the result of "accumulated damage" (assuming that is indeed the overarching mechanism).
Changes in brain chemistry are another thing that's probably not directly damage related as the declines start around mid 20's.
PS: Biology has a lot of odd edge cases, youngest mother is 5 oldest 74. http://en.wikipedia.org/wiki/List_of_youngest_birth_mothers
Re: Studies: Blood from young mice reverses aging in old mice
#40Earlier quoted context omitted.
Should be done outside the normal blood donor system. There's not that much donor blood around, so it would be unethical to use it. Not a practical problem, but it would look and feel bad. Anyway, yes, why not try this on humans? Sounds perfectly reasonable.
Because of cancer. As mentioned in the article: "Waking up stem cells might lead to their multiplying uncontrollably."