I swear to god, the day people finally realize they can actually block ads, we're going to have a massive collapse of the industry. Fear that day.
The lack of adblock options on mobile Safari and Chrome has to be a massive boon and a huge relief to advertisers. You can get third-party browsers that have some adblocking features, but I suspect the percentage of people on mobile who use them is in the low single digits.
I don't know about Safari.