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The worthlessness of Vitamin D is mildly exaggerated

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Re: The worthlessness of Vitamin D is mildly exaggerated

#31

Even so, it still seems to be a small effect. The author mentions some studies looking at sunlight vs all cause mortality. These, and more recent studies [1] found much higher reductions in all cause mortality from sunlight exposure, of about 30%. It's thought that other factors may be behind this, such as NO production in the skin in response to UV [2]. [1] https://pubmed.ncbi.nlm.nih.gov/32918215/ [2] https://karge…

Sunlight would likely get you all the "red light therapy" effects too.

Re: The worthlessness of Vitamin D is mildly exaggerated

#32

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

My life changed after I got tested for vit D and started talking supplements. I was severely deficient. I am now sufficient and everything changed for me.

In December by chance I put a pack of Vitamin D into my shopping basket. I did not think much, thought to take 1000IE but then decided that for the first week I take 3000 to catch up. Muscle pain went and control over eating improved. I did not expect any changes based on past experience with 1000 but this time I could not ignore it (age can play a role) and I stayed on 3000. Tests a month later showed I was just not deficient any-more. I continued on the regime and started having improvements in long running skin issues to the extent my dentist noticed. It may not be a miracle drug but one should not underestimate cumulative impact individual factors, age and lifestyle changes (less sun) that may change levels and demand.

Re: The worthlessness of Vitamin D is mildly exaggerated

#33

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

Ding ding ding.

People who are drawing blood and trying to find some correlation between vitamin presence and health at this point are just practicing divination. The fact that it can be published in a scientific journal without any sort of RCT to back it up is palpably unscientific.

The customers of these studies are the supplement companies looking for another product to sell.

Re: The worthlessness of Vitamin D is mildly exaggerated

#34

Your body needs vitamins in order to form complex aminos to operate. But your body only needs to make so many of them - especially if you are an adult, not pregnant, or not suffering from a disease of some sort. The very premise that loading up your body with "excess" vitamins beyond what you need is already pretty fraught. Building a house without enough lumber can lead to long term deficiency - but loading up a con…

Vitamin D deficiency entered the chat. It's a relatively common issue in many countries.

Re: The worthlessness of Vitamin D is mildly exaggerated

#35

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

My life changed after I got tested for vit D and started talking supplements. I was severely deficient. I am now sufficient and everything changed for me.

That doesn't undermine OP's point. Being deficient is unhealthy. But that doesn't mean an overabundance makes you healthier.

Re: The worthlessness of Vitamin D is mildly exaggerated

#37

Your body needs vitamins in order to form complex aminos to operate. But your body only needs to make so many of them - especially if you are an adult, not pregnant, or not suffering from a disease of some sort. The very premise that loading up your body with "excess" vitamins beyond what you need is already pretty fraught. Building a house without enough lumber can lead to long term deficiency - but loading up a con…

Vitamin D deficiency entered the chat. It's a relatively common issue in many countries.

That's fair, but it also exactly explains why there are weak positive effects of extra Vitamin D.

There's a lot of unknowingly deficient people out there who get benefits from supplements. But the benefits are limited by the upper bound of the deficiency.

Re: The worthlessness of Vitamin D is mildly exaggerated

#38
post #16

Earlier quoted context omitted.

On a slight tangent, if people are unaware, you can pay for and get just about any lab test without a prescription in the United States.

This is how I found my 10k IU of vitamin D a day, based on modern recommendations for indoor workers, that I modulate based on how much I'm outdoors, was perfectly on the mark!

Also an indoor worker. 10K IU daily would have put me far into hypervitaminosis D range.

Make sure you test after a very long time, such as a year of steady supplementation. A lot of the excess Vitamin D cases were taking less than 10K IU daily.

Re: The worthlessness of Vitamin D is mildly exaggerated

#39

This is great. I wonder if there's something like a patreon model where we could sponsor similar deep dives on other supplements? For example, I've been supplementing with nicotinamide riboside for a few years now. I stop occasionally and when I do stiff and sore hands and knees return and I get more headaches. I'd love to know if I'm deluding myself (placebo effect?) or there's good science that backs up my experien…

examine.com

Re: The worthlessness of Vitamin D is mildly exaggerated

#40
The survey in the article that assessed vitamin D deficiency was a bit odd:

>Because physical exams are performed in mobile vans in NHANES, data could not be collected in northern latitudes during the winter; instead data were collected in northern latitudes during summer and in southern latitudes in winter. To address this season-latitude aspect of the NHANES design, we stratified the sample into two seasonal subpopulations (winter/lower latitude and summer/higher latitude) before examining vitamin D status.

Yeah, I'm not surprised that the rates for vitamin D deficiency were low.

>Less than 1% of the winter/lower latitude subpopulation had vitamin D deficiency (25-OHD

and the more northern latitude in summer:

>With the exception of elderly women, prevalence rates of vitamin D insufficiency were lower in the summer/higher latitude subpopulation (

Now imagine if you lived in northern Europe around the 60th parallel, where the sun doesn't get high enough in winter to produce vitamin D.

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