Asbestos... Lead, CFCs, mercury, cadmium, radium, petroleum, DDT, BPA, microplastics, PFAS, organophosphates, pyrethrins... The more wonder materials turn out to be devastating for human health or environmental stability, the more I think maybe the "no (synthetic) chemicals" crowd have a point.
Or rather, that maybe we're learning the wrong lesson each time. Maybe instead of "asbestos is bad" or "DDT is bad", the real lesson should have been "biological and ecological systems are incredibly fragile outside of the exact combination of environmental conditions and chemical inputs they've specifically evolved to handle".
Too much complexity, too many delicate mechanisms and feedback loops. Can't afford to keep playing whack-a-mole, every generation we replace the old poisons and add some new ones. If we keep introducing new molecules and quantities of substances that evolution hasn't had a chance to adapt to, then we shouldn't be surprised that we keep breaking things.
But let's not pretend we don't use pesticides for a reason. People gotta eat, and pyrethrins are already an improvement AFAIU, less toxic to mammals, similar to molecules that exist in nature. But still, a cudgel. Maybe we need to take ecological engineering seriously, control pest species by simultaneously cultivating stable ecosystems of insectivores/predators and hyperparasites, poison spray not required...