Indeed. For people used to the "typical REPL" from Ruby, Python and alike, the best comparison I've found is this:
"Typical REPL" workflow: Have one editor open, have one REPL open, have one terminal open that runs the application. One change is typically: Experiment in the REPL window, copy-paste into your editor, write tests, restart application (lose all state), setup reproduction state, test change. Or something like this.
In a Clojure REPL workflow, you'd do something like: Have one editor open, this starts the REPL and often the application in the background too. One change is typically: Edit code, evaluate that snippet of code (which sends it to the REPL and the running application), write tests, evaluate them too in the editor, if you're happy, hit CTRL+S and you're done. Application still has the existing state, no restarts needed and you essentially never have to leave the editor window/pane.
Of course, others might have slightly different workflows, but for myself and many (most?) other Clojure developers I've observed in the wild, this is pretty much the standard.