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Universal vaccine against respiratory infections and allergens
31–40 of 159 posts
Re: Universal vaccine against respiratory infections and allergens
#32Appears that it is trying to stimulate broad immunity .. instead of any one specific virus/disease. Artificial and overstimulation of our immune systems long-term can't be healthy. Definitely a tradeoff here.
you would think so! as a "vaccine skeptic", i think this kind of research is important and patients should be able to decide w/ their doctor which to pursue based on their individual condition. perhaps this tradeoff will be worth it in higher risk individuals.
Re: Universal vaccine against respiratory infections and allergens
#333 weeks old story;
Some discussion: https://news.ycombinator.com/item?id=47080267
Re: Universal vaccine against respiratory infections and allergens
#34I don't know much about this, but wouldn't the description of this imply you're stimulating the body to be in an a long-term situation that would be commonly viewed as unpleasant (inflamed, maybe nasal drainage, that type of thing) with the positive tradeoff that you get fewer actual infections?
Or worse. If it is so easy to activate, there must be an evolutionary reason why we don’t have it.
I think you have evolution backwards. There only needs to not be a reason we need it to survive long enough to reproduce. Or more probabilistically, there needs to not be a significant reproductive benefit to it.
And bear in mind that most people don't have a problem surviving colds and the like long enough to reproduce even with no vaccines at all, and that was probably more true for much of our evolutionary history when we were living much more isolated lives, and not cohabiting with chickens and pigs.
Re: Universal vaccine against respiratory infections and allergens
#35Appears that it is trying to stimulate broad immunity .. instead of any one specific virus/disease. Artificial and overstimulation of our immune systems long-term can't be healthy. Definitely a tradeoff here.
It could also be useful in low doses to supplement, for example, a seasonal vaccine in a year where they are especially unsure about prevalent strains, or where their predictions were already proved wrong early in the flu season
Re: Universal vaccine against respiratory infections and allergens
#36Appears that it is trying to stimulate broad immunity .. instead of any one specific virus/disease. Artificial and overstimulation of our immune systems long-term can't be healthy. Definitely a tradeoff here.
Cant we say this applies to the flu vaccine? This almost validates why I skip it every year.
I get sick after getting the flu vaccine and feel pretty bad for 1-3 days... then I get the flu anyway because they picked the wrong ones.
Re: Universal vaccine against respiratory infections and allergens
#37Appears that it is trying to stimulate broad immunity .. instead of any one specific virus/disease. Artificial and overstimulation of our immune systems long-term can't be healthy. Definitely a tradeoff here.
> [greater activity within] our immune systems long-term can't be healthy
Not trying to be flip, but why? "Natural" isn't always better, and as the obesity epidemic has shown, our evolutionary past hasn't done a perfect job of preparing us for our current environment.
You might be right, but I'm skeptical that there is any non-extreme limit to something as simple and mechanical as our innate immune system.
Re: Universal vaccine against respiratory infections and allergens
#38I don't know much about this, but wouldn't the description of this imply you're stimulating the body to be in an a long-term situation that would be commonly viewed as unpleasant (inflamed, maybe nasal drainage, that type of thing) with the positive tradeoff that you get fewer actual infections?
People with severe allergies or at high risk would probably make the tradeoff even if side effects were a problem. If they're not a problem, I could see most people taking this regularly just to avoid the nuisance of respiratory infections.