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Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
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Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#32The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…
>after an acute SARS-CoV-2 infection. Maybe not all infections are considered "acute".
Acute, in this context, just means the infection had a finite (and usually relativity short) duration. The opposite is a chronic condition, which is what “long covid” would be in this case.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#3394% accuracy sounds extremely bad, no? https://www.ssph-journal.org/journals/public-health-reviews/... > Prevalence estimated (...) 2%–3.5% in primarily non-hospitalized children. So a fake test always saying "No" would be more accurate at 96.5% accuracy.
Sample size of 59 also seems worse than useless; I'm no researcher so maybe there's something I'm missing here but, doesn't seem very good. Junk science?
It's just an early study, not junk.
The primary conclusion of this research was basically just "this looks like it would be worth doing more research on." Which is a fair conclusion for a study this small.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#34The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…
I'm an ambulance chaser. I look at medical records all day. I've never seen anyone complaining of long covid.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#3594% accuracy sounds extremely bad, no? https://www.ssph-journal.org/journals/public-health-reviews/... > Prevalence estimated (...) 2%–3.5% in primarily non-hospitalized children. So a fake test always saying "No" would be more accurate at 96.5% accuracy.
If you read the actual link I don't think they're saying that using it as a covid test with some specific threshold of microclots has a 94% accuracy but just that the raw microclot count has a 94% accuracy. The title on hn which implies that seems to be inaccurate and it's not the original title of the article.
No, that does not seem to be what they are saying.
> We evaluated the diagnostic power of the device in a cohort of 45 LC patients and 14 healthy pediatric donors. We estimated a 94% accuracy for the microclot count using the devices, significantly higher than the traditional counting of microclots on slides (66% accuracy).
They are comparing the predictive power and using accuracy (instead of sensitivity, recall, F1, etc.). For their method "using the devices", they compute an accuracy of the predictive power, not of the count, of 94%. For the previous method they say the accuracy is 66%.
Basic questions: Is accuracy even a good metric for this? Is 94% a good value or just the difference between bad and very bad?
It might very well be that their improvement is from bad to really good, but the point is that a raw stat of "94% accuracy" is useless without context and so is the headline.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#36This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…
If this were the case you could do a natural study on this by comparing menstruating women with the rest of the population
Menstruating women don't lose nearly that much blood.
Even if they did, the hormonal effects would likely swamp anything else. Which is a huge problem: women are routinely excluded from studies to avoid that, meaning we have no idea what the effects are on women.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#37[dead]
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#38[dead]
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#39The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…
I have a 87 year old uncle who says he has long covid because he gets tired and needs a nap in the afternoon. I'm half the age and felt the same even before 2020.
Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients
#40The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…
It takes very severe disability for it not to be brushed off as depression, anxiety, burnout, or blamed on lifestyle.
Additionally, a lot of those numbers are based on earlier strains of COVID, which were much more severe.
I suspect the 1/5 figure is largely true for "has some degree of cardiovascular damage and worsened general health after COVID", but the number of people actually disabled by the condition is much lower.
That said, any loss of ability is a sad thing, and I am incredibly disappointed that we did not introduce any shared indoor space air quality legislation post-pandemic.