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whats "long covid" ? never heard of it
The reported phenomenon that you have long term effects after recovery.
As I understand it, unique to this specific corona virus.
The Molecular Basis of Long Covid Brain Fog
31–40 of 53 posts
Re: The Molecular Basis of Long Covid Brain Fog
#32In the unknown chemical factory of the brain it is very difficult to dealinate the begin and consequent steps of all degenerative diseases: Alzheimer's - Parkinson's, chronic fatigue syndrome - post-Covid, schizophrenia- autism etc. At most it is possible to discover an intermediate step.
Re: The Molecular Basis of Long Covid Brain Fog
#33The headline overstates the findings. The researchers aren't saying that this is the underlying basis of COVID brain fog. They hypothesized that AMPA receptors might be involved. They compared Long COVID patients to controls and found a difference. This doesn't mean that AMPA receptors are the root cause of post-COVD brain fog, nor does it necessarily mean that drugs modulating AMPA receptors could reverse it. It onl…
Sounds like the authors ought to have titled it: "Uncovering a Molecular correlation to Long COVID Brain Fog"
Which can still be extremely useful, for targeting further investigation.
Re: The Molecular Basis of Long Covid Brain Fog
#34The headline overstates the findings. The researchers aren't saying that this is the underlying basis of COVID brain fog. They hypothesized that AMPA receptors might be involved. They compared Long COVID patients to controls and found a difference. This doesn't mean that AMPA receptors are the root cause of post-COVD brain fog, nor does it necessarily mean that drugs modulating AMPA receptors could reverse it. It onl…
>The headline overstates the finding.
On a long covid news article? What are the chances!
Re: The Molecular Basis of Long Covid Brain Fog
#35The headline overstates the findings. The researchers aren't saying that this is the underlying basis of COVID brain fog. They hypothesized that AMPA receptors might be involved. They compared Long COVID patients to controls and found a difference. This doesn't mean that AMPA receptors are the root cause of post-COVD brain fog, nor does it necessarily mean that drugs modulating AMPA receptors could reverse it. It onl…
It does imply AMPA antagonists or NAMs might be of interest to people with this problem, though. I wonder if high-dose L-theanine might be of interest; most of the -ampanel family antagonists are liable to abuse and a little sketchy regarding side effects and *NQX family aren't usable outside lab settings, so limited other options. Memantine might help but itself has anecdotal reports of inducing brain fog.
I'd also remark that their methodology has issues; we do not have a clear etiology or diagnostic criteria for "long covid" and its presentation. Participants had previously been infected (this is essentially everyone) and reported subjective "brain fog" type symptoms which is a terrible way to attempt to isolate anything about this "long covid". It's possible this is just a generalized syndrome that results from behavioral or lifestyle factors. I.e. we have no way to know what is "long covid" versus other things, no way to reliably trust patient history, and no way to know we are seeing that particular type of "brain fog".
Re: The Molecular Basis of Long Covid Brain Fog
#36Earlier quoted context omitted.
Interesting! I feel I’ve been kinda foggy in my head since I quit smoking a year or two before covid and it then got worse with the pandemic. And I’ve felt there’s been more effect from a night out with party smoking than just seeing an old friend. Might need to try my own home grown snuff when it’s done and not just give it away.
Well aged leaf smells amazing. I've often thought about getting into pipe smoking, but my guess is its like coffee, it smells better than it tastes.
I don't smoke cigarettes or pipes, but at least with cigars, it's very easy to get into. You're tasting the smoke in this case, not inhaling it. You'll still get something of a buzz, since there are looooots of entry points into the bloodstream in the mouth, but even for someone like me who's a gigantic baby when it comes to inhaling smoke, it's easy-breezy to enjoy a cigar.
If you like smoked food, you'll love the taste of smoking. Though, I highly recommend limiting it to serious celebrations, for obvious reasons. I generally only have them at weddings.
Re: The Molecular Basis of Long Covid Brain Fog
#37There's so much we don't know about this yet. It's great to see new knowledge being generated! I had Covid last February (vaccinated and boosted, thankfully). It was a mild course, but I wound up sensitized to caffeine for three to four months after. I normally drink 100-150mg/day, but I had to cut that back to 50-60mg and only in the morning. It seems to have passed, so I'm back on my drip.
Mine has never recovered. I have to drink decaf now! I feel a small amount of relief that I'm not alone.
Slow Bloom's Decaf is the best I've tried, and I really like like Savorista's Swiss Water Ethiopian too. Both can yield a passable pourover.
You can also find some good decaf black tea. Jones Coffee Roasters in Pasadena stocks some, and I'll see it online occasionally.
Re: The Molecular Basis of Long Covid Brain Fog
#38Earlier quoted context omitted.
Mine has never recovered. I have to drink decaf now! I feel a small amount of relief that I'm not alone.
Slow Bloom's Decaf is the best I've tried, and I really like like Savorista's Swiss Water Ethiopian too. Both can yield a passable pourover. You can also find some good decaf black tea. Jones Coffee Roasters in Pasadena stocks some, and I'll see it online occasionally.
thanks, I appreciate the recommendations!
Re: The Molecular Basis of Long Covid Brain Fog
#39The biggest impact I've made on my brain fog (post COVID) is using nicotine. Even 2mg a day makes a big difference for me.
My meditation teacher says what works for him is cannabis.
Re: The Molecular Basis of Long Covid Brain Fog
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