Ugh, B6 a is part of the very popular ZMA...
For good reason. ZMA is taken for exercise and B6 is depleted by exercise.
High vitamin B6 doses over a long period could cause irreversible nerve damage
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Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#32Earlier quoted context omitted.
There was an interesting video by ChubbyEmu where energy drinks fixed his B12 deficiency by accident that caused the insomnia: https://www.youtube.com/watch?v=d_qKA6KTvs8
I've tried many supplements and narrowed it down to B6 and magnesium. B12 had no effect. Insomnia can of course manifest itself through many causes, but taking energy drinks would definitely help very few. B12 is something the body stores so your lifestyle and diet must be quite shit to have a deficiency. Magnesium and B6 on the other hand you can become deficient very quickly.
This makes sense when you consider the role that magnesium has in the body - it's involved in a lot of reactions, either directly or as a cofactor.
In fact, ATP exists typically as MG-ATP in the body.
Severe Deficiency is rare (or rarely diagnosed i should say) because the body maintains serum magnesium levels at the expense of skeletal mg.
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#33I've had on and off insomnia for 20 years, mostly on and quite severe. If I exercised it got way worse, if I got sick sleep was practically impossible. B6 and magnesium have done absolute wonders for my well being. I also had problems with irritability. Especially if I got hurt in some way (like sprained wrist). If I get this way now, it is a clear sign I need to take B6. It fixes it right up. Both elements are somet…
Melatonin may have a negative effect on sleep in people under 40. In my case this was expressed as waking up early or in the middle of the night and being unable to go back to sleep.
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#34Earlier quoted context omitted.
Interesting, is the site yours?
Yep.
Replying to my own comment: I've also removed the paywall on the magnesium article since someone in the thread mentioned it
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#35Happened to me too. I had been consuming two energy drinks per day for a week or so and then my SO (who's addicted to vitamin supplements) gave me some multivitamins that I took just to be nice. Apparently that pushed me over the edge. After one night and day of sweating profusely and feeling really bad, and me thinking I've cached a bug on my daily public commute, I didn't think about it any more, until days later w…
Huh, so maybe Prince Andrew wasn't lying
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#36It's kind of unbelievable that something that sounds so “harmless” like vitamins can actually pose serious risks when taken in high doses over a long period. The word “supplement” tends to give us a false sense of security, as if it must be safe by default. A lot of friends have told me that taking multivitamins is good for your health, but I’ve always been hesitant. I’ve felt that fresh fruit and a balanced diet are the more natural ways to nourish the body.
Reading this article and the shared experiences here really surprised me. I had no idea vitamin B6 could affect different people in such dramatically different ways. Some seem to benefit, while others suffer from nerve issues. It makes me think maybe we’re too quick to assume more is better, and forget that what fits you is probably the most important thing.
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#37It's kind of unbelievable that something that sounds so “harmless” like vitamins can actually pose serious risks when taken in high doses over a long period. The word “supplement” tends to give us a false sense of security, as if it must be safe by default. A lot of friends have told me that taking multivitamins is good for your health, but I’ve always been hesitant. I’ve felt that fresh fruit and a balanced diet are…
Fun fact: dont eat polar bear liver, you will get vitamin A poisoning.
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#38I've had on and off insomnia for 20 years, mostly on and quite severe. If I exercised it got way worse, if I got sick sleep was practically impossible. B6 and magnesium have done absolute wonders for my well being. I also had problems with irritability. Especially if I got hurt in some way (like sprained wrist). If I get this way now, it is a clear sign I need to take B6. It fixes it right up. Both elements are somet…
The problem is that some processes in the human body might, in some people, require more of a vitamin, and others require normal amounts. So if you start "fixing" your problems with megadosing, then chances are you will still get side effects.
Re: High vitamin B6 doses over a long period could cause irreversible nerve damage
#39Why do people take multivitamin any how?