On 17th century "cocaine"

Post by [deleted] » Thu, Oct 10, 2024, 12:57 AM UTC

JumpCrisscross wrote: post #20

Mtinie wrote: post #16

Earlier quoted context omitted.

They were using cocaine. It was a less concentrated form, sure, but it’s still using the same substance for a psychoactive effect.

> were using cocaine. It was a less concentrated form, sure I was going to say this is pedantically correct, but on closer inspection, it's not even that. Cocaine, the chemical, is present in both coca leaves and cocaine, the drug. When people say cocaine--particularly in this context--they're referring to cocaine the drug, not cocaine the chemical. Cocaine the drug and cocaine the chemical are homonyms, and it's inc…

Post by brcmthrowaway » Thu, Oct 10, 2024, 1:09 AM UTC

Clamchop wrote: post #12

IAmGraydon wrote: post #6

>As you can see, the Times was not the only news outlet to be confused about the distinction between cocaine and coca Unfortunately, the author of this article is the one who is confused. Cocaine is the name of the alkaloid present in the coca leaf, much like the coffee bean contains caffeine. If they were using coca leaf, they were using cocaine.

TFA literally already says what you said. They're making a reasonable distinction between chewing coca leaves for mild stimulant effect and huffing a fat rail of the pure stuff. It gives the wrong idea to say these 17th century people were doing cocaïne.

Post by cjbgkagh » Thu, Oct 10, 2024, 1:13 AM UTC

brcmthrowaway wrote: post #32

cjbgkagh wrote: post #30

Earlier quoted context omitted.

If I’ve gone a long time without caffeine a single coffee could keep me awake up for two consecutive all nighters. As a regular drinker I still cannot handle more than one cup of coffee per day. It turns out that I have a number of genes that increase the intensity and the duration of effect. I think genes explain most of the differences in experiences with caffeine.

Have you done a whole genome study?

Post by brcmthrowaway » Thu, Oct 10, 2024, 1:14 AM UTC

cjbgkagh wrote: post #35

brcmthrowaway wrote: post #32

Earlier quoted context omitted.

Have you done a whole genome study?

Yes, a 30x WGS, I recommend it to everyone and you only have to do it once.

Post by valec » Thu, Oct 10, 2024, 1:31 AM UTC

cjbgkagh wrote: post #30

_yb2s wrote: post #24

Earlier quoted context omitted.

Caffeine affects people differently… it has very intense effects on me- I would never call it “very very mild”

If I’ve gone a long time without caffeine a single coffee could keep me awake up for two consecutive all nighters. As a regular drinker I still cannot handle more than one cup of coffee per day. It turns out that I have a number of genes that increase the intensity and the duration of effect. I think genes explain most of the differences in experiences with caffeine.