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Blockbuster Alzheimer's paper retracted by former Stanford president

stanforddaily.com

31–40 of 143 posts

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#31

For those not familiar, this is the paper which first proposed the amyliod plaque theory (the original link mentions protiens, but not beta-amyloid or Tau specifically). https://www.drugdiscoverynews.com/what-now-for-the-amyloid-h...

Wow, even as a lay person I hear other lay people talk about amyloid plaque. It’s scary to know how far into common knowledge misinformation can burrow.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#32
post #26

Earlier quoted context omitted.

They’re all wrought with dishonesty and self preservation.

Jennifer Doudna [1], who helped characterize* CRISPR, worked at Yale: > Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. ... and now works at UC Berkeley. David Liu [2], who pioneered base editing, a generational improvement on classic CRISPR, works at Broad Institute (which is a collab between Harvard and MIT): > He is the Richard Merkin Professor, Director…

> Are there shitheads in these institutions? Undoubtedly. Are there also a ton of really brilliant people who have good intentions, have integrity, and deserve your utmost respect? Undoubtedly.

Right, that is the nature of every human institution, and every human.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#33
post #26

Earlier quoted context omitted.

They’re all wrought with dishonesty and self preservation.

Jennifer Doudna [1], who helped characterize* CRISPR, worked at Yale: > Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. ... and now works at UC Berkeley. David Liu [2], who pioneered base editing, a generational improvement on classic CRISPR, works at Broad Institute (which is a collab between Harvard and MIT): > He is the Richard Merkin Professor, Director…

Doudna didnt discover CRISPR; her fellow Nobel recipient Emmanuelle Charpentier did

https://en.wikipedia.org/wiki/Emmanuelle_Charpentier?wprov=s...

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#34
> This retraction is Tessier-Lavigne’s fourth in as many months, a stunning turn of events for a researcher of his stature.

That says a lot about how worthless the whole science journal and peer review process is. At this rate your assumption is that 50% of what is published is complete junk.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#36

Still a good place to study, though.

> good place to study

I work with a lot of Stanford grads. They’re terrific folk.

But the concentration of corruption, delusion and depravity in its graduates, professors and administration begin to make one question if they were great and collected and resisted Stanford’s transformative effect, which increasingly (albeit with low confidence) looks like it may be net negative, or if they were transformed positively by the experience.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#37
post #11

Earlier quoted context omitted.

What was the interview pass rate for MIT grads and people without a college education?

Given that MIT grads are objectively superior to the rest of us that didn't get into any elite schools in basically every dimension I'd wager it's fairly high. With that said, the Square interview process isn't as algorithmic as most tech or finance companies and is instead more collaborative, so the raw IQ most MIT grads would use for their Jane Street interviews probably doesn't apply here.

> Given that MIT grads are objectively superior to the rest of us that didn't get into any elite schools in basically every dimension I'd wager it's fairly high.

Genuflect when you say that fella.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#38
post #9

Earlier quoted context omitted.

Why are you grouping MIT into the same group as Stanford?

In a positive sense, they are the two top tech oriented universities, west coast and east coast counterparts. In the negative, you have this story at Stanford. With MIT you have the Jeffery Epstein connection, some high profile retractions, and the president part of the three Uni Presidents who flubbed the anti-semitism question in the congressional hearing.

Other universities have negatives too, but they are not newsworthy at lesser known schools. The heads of lesser-known schools aren't featured in Congressional hearings.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#39
post #34

> This retraction is Tessier-Lavigne’s fourth in as many months, a stunning turn of events for a researcher of his stature. That says a lot about how worthless the whole science journal and peer review process is. At this rate your assumption is that 50% of what is published is complete junk.

That would be a far less scientific, and true, conclusion than what was in the papers.

From the article:

> Retractions remain exceedingly rare for scientific papers: Just eight out of every 10,000 are retracted, according to a Retraction Watch database.

Re: Blockbuster Alzheimer's paper retracted by former Stanford president

#40
post #26

Earlier quoted context omitted.

They’re all wrought with dishonesty and self preservation.

Jennifer Doudna [1], who helped characterize* CRISPR, worked at Yale: > Doudna joined Yale's Department of Molecular Biophysics and Biochemistry as an assistant professor in 1994. ... and now works at UC Berkeley. David Liu [2], who pioneered base editing, a generational improvement on classic CRISPR, works at Broad Institute (which is a collab between Harvard and MIT): > He is the Richard Merkin Professor, Director…

When I say “they” not referring to individuals. I’m referring to the organization at a whole. It’s ironic that so many who operate under the umbrella of science and truth do things that are antithetical to that. At the end of the day these institutions are fighting for survival like everyone else - and they don’t always operate truthfully.
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