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Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

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Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#31
post #7

Earlier quoted context omitted.

I am not a biologist but I've known a few in my time; It is highly unlikely there will ever be a singular "cure for cancer" as cancer is a bit of a blanket term given to multiple diseases, however this is a seemingly reasonably good breakthrough in treatment - being able to destroy cancerous cells without exposing the patient to further harm via targeted radiation or harsh chemo drugs (basically targeted poisoning) f…

Or better yet find out how to prevent cancers since it's better to not be sick than to treat you once you are sick. Things like the HPV vaccine which in my province saw a 90% drop in just a few years. I think everyone should get it no questions asked which maybe they don't anymore? The Hepatitis B vaccine too since having the disease is a cause of liver cancer. But if all else fails it's also good to have a tools to…

Preventing cancer seems like a fool's based on my understanding of the disease. You have cancerous cells in your body every single day. Your immune system kills them all off. It's like saying you want to prevent all bacteria from entering your body. It's just not realistic (at least, not right now).

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#32
How many times have we found a new medical use for an existing dye?

Prontosil was a pre-penicillin antibacterial based on azo dyes https://en.wikipedia.org/wiki/Prontosil#History

Brilliant blue, a food coloring, was found to help repair spinal injuries https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719612/

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#33
post #7

Earlier quoted context omitted.

I am not a biologist but I've known a few in my time; It is highly unlikely there will ever be a singular "cure for cancer" as cancer is a bit of a blanket term given to multiple diseases, however this is a seemingly reasonably good breakthrough in treatment - being able to destroy cancerous cells without exposing the patient to further harm via targeted radiation or harsh chemo drugs (basically targeted poisoning) f…

Or better yet find out how to prevent cancers since it's better to not be sick than to treat you once you are sick. Things like the HPV vaccine which in my province saw a 90% drop in just a few years. I think everyone should get it no questions asked which maybe they don't anymore? The Hepatitis B vaccine too since having the disease is a cause of liver cancer. But if all else fails it's also good to have a tools to…

Whales are fairly resistant to cancers (and so are other mammals, such as bats or naked mole rats), at least compared to humans.

Possibly, we may one day run DNA modifications on ourselves to copy whale/bat/naked mole rat genes into our cells in order to acquire similar protection.

Sounds wild, but it once sounded wild to infect yourself with a cowpox pus in order to prevent human smallpox.

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#34
post #31

Earlier quoted context omitted.

Or better yet find out how to prevent cancers since it's better to not be sick than to treat you once you are sick. Things like the HPV vaccine which in my province saw a 90% drop in just a few years. I think everyone should get it no questions asked which maybe they don't anymore? The Hepatitis B vaccine too since having the disease is a cause of liver cancer. But if all else fails it's also good to have a tools to…

Preventing cancer seems like a fool's based on my understanding of the disease. You have cancerous cells in your body every single day. Your immune system kills them all off. It's like saying you want to prevent all bacteria from entering your body. It's just not realistic (at least, not right now).

Maybe the OP meant "prevention" in the sense of "improving your immune system so much that cancer never manifests as a disease".

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#35
post #31

Earlier quoted context omitted.

Or better yet find out how to prevent cancers since it's better to not be sick than to treat you once you are sick. Things like the HPV vaccine which in my province saw a 90% drop in just a few years. I think everyone should get it no questions asked which maybe they don't anymore? The Hepatitis B vaccine too since having the disease is a cause of liver cancer. But if all else fails it's also good to have a tools to…

Preventing cancer seems like a fool's based on my understanding of the disease. You have cancerous cells in your body every single day. Your immune system kills them all off. It's like saying you want to prevent all bacteria from entering your body. It's just not realistic (at least, not right now).

Replying to a post noting a 90% reduction in cancer thanks to the HPV vaccine with "preventing cancer seems like a fool's errand" is pretty amazing. Would you care to expand on that?

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#36
post #31

Earlier quoted context omitted.

Preventing cancer seems like a fool's based on my understanding of the disease. You have cancerous cells in your body every single day. Your immune system kills them all off. It's like saying you want to prevent all bacteria from entering your body. It's just not realistic (at least, not right now).

Maybe the OP meant "prevention" in the sense of "improving your immune system so much that cancer never manifests as a disease".

HPV causes cancer. The prevention here is literal - by preventing infection from the oncogenic HPV variants there is no cancer.

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#37
post #5

> Near-infrared light can go as deep as 10 centimeters (~ 4 inches) into the human body. This attribute of the infrared light is key to treating cancer anywhere in the human body with this method. As long as the patient is not obese, I assume 10 centimeters of penetration depth are enough to reach any part of the body. Penetration depth and the precision of the desired effect is something that is very important in ra…

With laparoscopy, you can penetrate patients of all sizes with instruments, and with minimal danger.

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#38

How many times have we found a new medical use for an existing dye? Prontosil was a pre-penicillin antibacterial based on azo dyes https://en.wikipedia.org/wiki/Prontosil#History Brilliant blue, a food coloring, was found to help repair spinal injuries https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719612/

The blue dye seems to have gone nowhere since the initial study: https://en.wikipedia.org/wiki/Coomassie_brilliant_blue

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#39

How many times have we found a new medical use for an existing dye? Prontosil was a pre-penicillin antibacterial based on azo dyes https://en.wikipedia.org/wiki/Prontosil#History Brilliant blue, a food coloring, was found to help repair spinal injuries https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719612/

And the first antibiotic was inspired by the observation that dye stuck to bacteria better than other things! See https://en.wikipedia.org/wiki/Paul_Ehrlich

Re: Light-induced whole-molecule vibration can rupture melanoma cells’ membrane

#40
> whole-molecule vibration Heating it up

> Light-induced with IR light (IR penetrates tissue much better than visible/UV and it's cheaper than microwaves/RF)

> can rupture melanoma cells’ membrane you can cook cancer to death, surprise. The big deal is not cooking everything else, ~~here accomplished with a targeted sensitizer dye that localizes to just those cells~~ Nope, no targeting at all. The advance here is just a new class of IR absorbing dyes that have some cool chemical properties that lend themselves particularly well to disrupting lipid membranes. The reason it's billed as a cancer treatment is because the authors get funding from NIH not NSF, more or less

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