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Calorie restriction in humans builds strong muscle and stimulates healthy aging

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Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#31

Any calorie based study when it's self reported should be highly suspect of being false.

Participants also lost weight and muscle mass in this study. 12% calorie restriction and 10% weight loss maintained over 2 years (avg weight reduction of 7.5 kg vs 0.1 kg weight increase in control group), of which 71% was fat loss.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#32
post #14
post #7

12% reduction of what? The basal metabolism? Were the people overeating before? How many calories on average?

I never get this "calorie restriction" term. What does it mean? I have a BMI of 20. Should I reduce my intake by 12%? When do I stop reducing? I want to live longer. I would also like to build some more muscle, ideally to a BMI of 22. What if I gain 10lbs of muscle then restrict?

It just means eating 12% fewer calories than your baseline to maintain your current weight. So if you eat 2,500 calories per day to keep your weight and activity levels, bump it down to 2,200 and keep it there. I have heard that it is possible to build muscle while "cutting" (calorie restricting) but it's going to be much slower and probably more uncomfortable. Note that this study was a 12% restriction maintained for 2 years. The metabolic and inflammatory benefits persist long after the calorie restriction period in animal models, and this study seems to show the same genetic pathways are getting upregulated and downregulated in humans as we have seen in the animals that benefit from longer lifespan after calorie restricting.

When you put on 10 lbs of muscle, presumably your baseline will be slightly higher than it was prior to that (extra muscle requires extra calories to maintain), but still less than what it took to put that muscle on quickly and efficiently. I have no clue how much you should expect that difference to be, I'm sure many a bro scientist has opinions on it, some of which may be reasonable. Bulking and cutting is a classic technique in bodybuilding, however, typical cuts go on for a few months at most as opposed to 2 years.

One major takeaway from this study is that on average, you will be just as strong as when you started calorie restricting even though you will have lost muscle mass. It is theorized that your muscles will have become more efficient, so if you put on more muscle after a long period of calorie restriction you will be considerably stronger than if you had skipped the calorie restriction and just added the muscle. Food for thought.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#33
post #24

Does any one find hard to eat a lot of protein (150g) in a 8 hour feeding window? I hate to live off of protein shacks.

I'm sure this won't be enjoyable to many people, and only works well for certain meals, but my secret weapon is gelatin powder. Mix with water until paste forms in your bowl then put steaming hot food on top and it will turn into a kind of 'creamy' sauce-like consistency. Nice mouth feel without too much flavor.

Oh, and learning to cook meat/protein so it is tender, browned, flavorful, and seasoned properly. It also seems like acid is way under-utilized in a lot of lazy / American style cooking. Helps a lot with palatability and digestion to use lime juice, rice vinegar, and other acidic ingredients during the cooking process.

Eat more veggies, too. They are full of digestive enzymes, but most veggies don't add too many calories.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#34
post #24

Does any one find hard to eat a lot of protein (150g) in a 8 hour feeding window? I hate to live off of protein shacks.

Why 8hr? For the entire day eat 5 times and 200 plus grams is very doable. I only have one scoop of whey, and sometimes a bar, but everything else is lean Protein or carbs and fat that also have protein (oats, pb, yogurt)

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#35
post #5

I did a bit of a double-take at the headline because it seems to imply that one can grow stronger while calorie-restricted, which is contrary to common practice around strength development - caloric surplus is generally understood to be necessary for muscle growth. I've only read the abstract, but the title as I interpreted it seems misleading: > One study showed that individuals on calorie restriction lost muscle ma…

I'm probably leaving way too much information on myself on this website, but Anne Debouté, a french kayakist (won France Championship, top 8 in a world cup) told me she ate a lot after the competion season, but 5 month later (in the 90s), she cut her calory intake and lost up to 15 kg. Her trainer was skeptical, but she did it every year and told me she really felt relatively stronger despite being less muscular, so i guess she was right in the end, and her trainer wrong. I'll bookmark this.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#36

Any calorie based study when it's self reported should be highly suspect of being false.

One of my favorite studies, an oft-replicated and cited study, tracks several hundred people who claimed to be "diet resistant". Using a technique invloving "doubly-lableled water" they were able to determine that every single person in the study who claimed to be diet resistant was overreporting their exercise and underreporting their calorie intake: https://www.nejm.org/doi/full/10.1056/nejm199212313272701 Of cours…

Is it supposed to be surprising that someone having weight issues would have issues reliably tracking the impacts of actions that would lead to their weight?

Have any similar "favorite studies" on hand about alcoholics who underreport alcohol use and overreport abstaining? Punching down is a favorite pastime of mine too btw :)

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#37
post #29

Earlier quoted context omitted.

Do you really need that much protein though?

That’s quite a contentious question, there aren’t that many good studies, and they are difficult to do well

It’s really not: https://examine.com/guides/protein-intake/. There is tons of quality research quoted on examine.com, and the results around protein are very conclusive. The short answer is that the recommendations are for much higher protein intake than most people think, and than most standard food will give you.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#38
> One study showed that individuals on calorie restriction lost muscle mass and an average of 20 pounds of weight over the first year and maintained their weight for the second year. However, despite losing muscle mass, calorie restriction participants did not lose muscle strength, indicating calorie restriction improved the amount of force generated by each unit of muscle mass, called muscle specific force.

If people lost 20 lbs in the first year of a 12% calorie restricted diet then that means that this study took place among people who were already obese (which seems extremely relevant). Anyone who is in good shape and not 6'8 is in no position to lose 20 lbs without serious risks to their health, aside from vastly decreased muscle strength. It is interesting, but not very surprising, that obese people with atrophied muscles don't lose "strength" by cutting calories and losing some muscle mass, which is very low to begin with.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#39

Earlier quoted context omitted.

> which is contrary to common practice around strength development This belief is already changing in bodybuilding and strength circles. Surprisingly, the fitness influencers on tiktok are leading the charge in changing minds about this.

That Ukrainian guy on tiktok who only weighs around 80kg but can deadlift over 270kg.

Anatoly. Very fun channel on YouTube.

Re: Calorie restriction in humans builds strong muscle and stimulates healthy aging

#40

Earlier quoted context omitted.

Wrestling seems like exactly the wrong thing to cite here, since it's generally not done in openweight, and if you're wrestling in traditional weight classes then what's described here is hugely beneficial - you can drop a weight class but not lose strength.

Also your opponent would have an advantage of you being lighter, which affects the results

Except both you and your opponent would be using tricks to be lighter (e.g. not drinking at least 1 day before the weighing)
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