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Reduced cancer mortality with daily Vitamin D intake

dkfz.de

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Re: Reduced cancer mortality with daily Vitamin D intake

#31

Earlier quoted context omitted.

My takeaway is to keep eating fish.

No, you'd basically have to eat salmon all day long every day to have any meaningful effect. Eating fish is not a viable or realistic way of maintaining healthy vitamin D levels. You have to either get sunlight or take a supplement. (And I love fish, I eat salmon daily sometimes, but I still supplement with D3.)

For D3, yes. But for Omega-3's, a little bit of salmon goes a looooong way.

Re: Reduced cancer mortality with daily Vitamin D intake

#32

I've been taking a daily vitamin D supplement since COVID-19 broke out in the USA. I believe there's a lot of evidence that many people are deficient in vitamin D. I don't know if supplements are the best way to attack that but it's one of the easiest ways. Getting daily sun exposure isn't always convenient and not really possible for a good chunk of the year since we have real winter here.

> I believe there's a lot of evidence that many people are deficient in vitamin D.

This brings up something I always wonder when these things come up. I agree with what you said, and there's a lot of evidence that this is bad. But I've seen mixed results over time as to whether or not vitamin d supplementation has a beneficial effect. I assume it's an "it depends on the effect" and sometimes yes and sometimes no

Re: Reduced cancer mortality with daily Vitamin D intake

#33

Earlier quoted context omitted.

D3 (animal-based) > D2 (plant-based) > D1 (synthetic), at least in humans if you read the literature, that is. The fishy thing is how actual scientists do whole studies using only D1 and then draw conclusions.

My takeaway is to keep eating fish.

Be careful with that (if you're treating cancer): https://www.cancernetwork.com/view/fish-oil-consumption-link...

Im not sure where this study landed in cancer communities or what subsequent studies concluded. But it's worth noting.

Re: Reduced cancer mortality with daily Vitamin D intake

#36

Earlier quoted context omitted.

My takeaway is to keep eating fish.

Overfishing is serious enough at this point that I'd rather take a small health risk than contribute to it.

Not sure why you are being downvoted. Salmon (mentioned in other siblings) is a perfect example of over fishing, and the farmed stuff tends to be of terrible quality and fed absolute garbage/treated terribly.

Re: Reduced cancer mortality with daily Vitamin D intake

#37

Earlier quoted context omitted.

D3 (animal-based) > D2 (plant-based) > D1 (synthetic), at least in humans if you read the literature, that is. The fishy thing is how actual scientists do whole studies using only D1 and then draw conclusions.

My takeaway is to keep eating fish.

Fish seem to be a very important component of the most healthful human diets, AFAIK, likely/mostly grounded in various aspects of evolution - some more on the side of actual 'selection pressure', some more on the side of chance and 'doesn't break things in a way that really matters' (i.e., successful enough reproduction / survival until ages required for reproduction).

That said, and in light of the comment from https://news.ycombinator.com/user?id=AlecSchueler, in particular - many of the most essential nutrients / 'micronutrients' that are obtained from eating fish are actually not made by fish themselves. Rather, fish 'concentrate' these substances as they go about their own business of survival. For example, vitamin D3, DHA, EPA, etc. Consequently, there are much more readily available 'vegan' sources of these substances, derived directly from the fundamental source(s) - microalgae and the like.

FYI (to all).

Overfishing IS a serious problem. Our activities, in general, are at a scale, and grounded in processes, these days, that produce significant impacts on the environment. Frankly, in the 'great scheme' of things, it doesn't matter a whit. Humans, and even this planet, are not even a droplet in the ocean of the universe, as far as we / I can even get any sort of a solid handle on that concept, now. But, that doesn't absolve us of any responsibility for trying not to absolutely annihilate OUR home.

It's disgusting to be GIVEN so much (none of us had much hand in almost anything that exists now, even what we've 'built' - we can't create atoms, we don't choose when, where, or to whom we are born, many of the opportunities we are afforded in a 'given life', etc.), and treat it as casually as so many do - to be so entitled as many seem to be.

But then, the universe (/ God / gods / whatever concept you prefer) will always have the final say. It'd just be nice to not F things up for everyone else, IMO.

EDIT: I hope the latter bits, above, don't come off as too moralizing - not my intention ... it's difficult to avoid some frustration with some of what the news inundates us with every day, I find.

More importantly - vitamin D3 is also readily produced in our own bodies with enough of the right kind of sunlight (dependent also on skin tone, age, kidney & liver function [etc.], and, ultimately, 'height of the sun in the sky' - i.e., enough ~290-300nm UV rays penetrating the atmosphere at the angle of inclination / solar zenith angle / whichever concept/quantification you prefer). And, this is actually not much at all. While skin cancer is, itself, a risk - this should, of course, be weighed against the importance of vitamin D3 itself. This comment is already REALLY long, but basically, for latitudes close enough to the 'Tropics', typically only 10 - 20 minutes of sun around noon in summer would be necessary. Winter is trickier. Here are a few links that may be useful for more info (in general, Pubmed - searching for review articles, etc. - is usually a good place to start, IMO - depending on how comfortable you are with reading these types of articles, otherwise, backtracing to those that cite them, especially, the efforts at more 'popular press' descriptions of research now produced by journals like Science etc.):

https://pubmed.ncbi.nlm.nih.gov/32918212/

https://pubmed.ncbi.nlm.nih.gov/28516265/

https://academic.oup.com/ajcn/article/110/1/150/5487983

... The 'Linus Pauling Institute' also seems to have, in my past experience, quite good information on 'micronutrients', in particular (with good citations, etc.), for all of Pauling's actual more tenuous beliefs (himself, in later life) about vitamin C:

https://lpi.oregonstate.edu/mic/vitamins/vitamin-D

Re: Reduced cancer mortality with daily Vitamin D intake

#38

I've been taking a daily vitamin D supplement since COVID-19 broke out in the USA. I believe there's a lot of evidence that many people are deficient in vitamin D. I don't know if supplements are the best way to attack that but it's one of the easiest ways. Getting daily sun exposure isn't always convenient and not really possible for a good chunk of the year since we have real winter here.

I have some hard numbers on this in my own health. I'm a pasty north European living in California and I get plenty of sunshine, as I enjoy the outdoors. As I got older, I got increasingly more viral infections and strep throat was a twice a year affair. It didn't occur to me that I could be vitamin-D deficient, but I was, severely. For some reason, 10+ hours of sunshine a week isn't enough for me to make my own. Ove…

> Over months, I tracked my blood vitamin D levels

OOC what did you use to do this?

Re: Reduced cancer mortality with daily Vitamin D intake

#39
post #38

Earlier quoted context omitted.

I have some hard numbers on this in my own health. I'm a pasty north European living in California and I get plenty of sunshine, as I enjoy the outdoors. As I got older, I got increasingly more viral infections and strep throat was a twice a year affair. It didn't occur to me that I could be vitamin-D deficient, but I was, severely. For some reason, 10+ hours of sunshine a week isn't enough for me to make my own. Ove…

> Over months, I tracked my blood vitamin D levels OOC what did you use to do this?

Monthly blood tests prescribed by a doctor at a local bloodwork lab.
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