Legalized cocaine would be tested for fentanyl and other potential contaminants.
Fentanyl vaccine tested in rats
31–40 of 378 posts
Re: Fentanyl vaccine tested in rats
#32Pray you then never get cancer or other nasty shit that requires proper painkillers.
Re: Fentanyl vaccine tested in rats
#33Pray you then never get cancer or other nasty shit that requires proper painkillers.
The article mentions that it’s specifically targeted at fentanyl and doesn’t interact with other opioids such as morphine
Re: Fentanyl vaccine tested in rats
#34As I understand it, this would have significant negative impact on anesthesia.
Although fentanyl is used for anesthesia, especially for deep sedation, it is not the only option. From the article: “The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile So they could still use other opioids for anes…
https://www.reddit.com/r/science/comments/yvnr4n/comment/iwg...
"So I’m an anesthesiologist. This vaccine would wreak havoc with surgery. Fentanyl is the go-to opioid for surgery. If you can’t use fentanyl then sufentanil can be used instead. Both are desirable because they have durations of under an hour which allows for surgical analgesia but still waking the patient after the procedure. The abstract here says the vaccine blocks both fentanyl and sufentanil. They don’t mention alfentanyl or remifentanil which would be the remaining options. Morphine, hydromorphone, codeine etc are all inappropriate for short surgical cases as the sole opioid because their durations of action are closer to 4 hours."
Re: Fentanyl vaccine tested in rats
#35I can imagine such a thing being a double-edged sword, in that it blocks the analgesic effects of the drug as well as the high. Doubly so if this one is a success and they make similar versions targeting other addictive painkillers. I can imagine people taking the vaccine proactively (the normal way people think about vaccines, after all) from the perspective of, "I don't want to become an addict, I better take this!…
> and this would only affect secondary harms (relapse).
But this is a HUGE step. If you could drop the relapse rate, that would be a major accomplishment.
Re: Fentanyl vaccine tested in rats
#36Pray you then never get cancer or other nasty shit that requires proper painkillers.
The article mentions that it’s specifically targeted at fentanyl and doesn’t interact with other opioids such as morphine
And fentanyl specifically exists because of the downsides of other opioids such as morphine.
Re: Fentanyl vaccine tested in rats
#37Earlier quoted context omitted.
Let's go another way with this: You are extremely unlikely to ever come across a fentanyl user, even if you work for law enforcement, even if you're a LEO in a major metro. 10x people died of heart attacks than any opioid, not only fentenyl, over the past few years. Almost as many people died of cancer as heart attacks, and half as many people died of COVID as cancer. Obviously, you can't equate research with other r…
> Let's go another way with this: You are extremely unlikely to ever come across a fentanyl user, even if you work for law enforcement, even if you're a LEO in a major metro. I'm gonna need a citation for that outrageous claim > Obviously, you can't equate research with other research; research and the drive to do research as a researcher is not a fungible item, but if we're spending tax payer money on it, why not a…
> Because that is nonsense. We don’t have that technology.
https://www.theringer.com/2023/1/20/23562871/america-isnt-re...
Re: Fentanyl vaccine tested in rats
#38Earlier quoted context omitted.
Is there some group of people who are taking fentanyl en masse intentionally? I know a few people who have died after taking what they thought were bars or ecstasy and died because it was laced with fentanyl. I know 0 who go out of their way to find and take fentanyl.
Yes people take fentanyl intentionally. The real heroin, the real opioid pills, and other forms of opioids have mostly dried up. Now we get fentanyl and fentanyl analogs, and other potent synthetic opioids that aren't well tracked. The reason is that it's extremely potent so it's easier to smuggle from China, Mexico, wherever it's being made. So now you get "pressies" [homemade pressed pills] which is diluted fentany…
> The reason is that it's extremely potent so it's easier to smuggle from China, Mexico, wherever it's being made.
Which is also why this won't work. Even 100% of the population were vaccinated against fentanyl, the end result would just be even more deaths because dealers would switch to using carfentanyl.
Re: Fentanyl vaccine tested in rats
#39Earlier quoted context omitted.
A vaccine doesn't work unless it helps the tiny fraction of fentenyl deaths who unintentnially take the drug? How about this: You're less likely to come in contact with the drug if there are fewer users getting high off it.
And how do you propose we get all the users vaccinated with the fentanyl jab? Another round of mass vaccinations? Make all the kids in school do it? Forced vaccinations for anyone in jail or rehab? Honestly, all of those seem like bad ideas.
Didn't we already do it? Ban people from working if they don't take it, maybe take away any benefits too. Don't allow them to public places?
Re: Fentanyl vaccine tested in rats
#40Earlier quoted context omitted.
Is there some group of people who are taking fentanyl en masse intentionally? I know a few people who have died after taking what they thought were bars or ecstasy and died because it was laced with fentanyl. I know 0 who go out of their way to find and take fentanyl.
Yes people take fentanyl intentionally. The real heroin, the real opioid pills, and other forms of opioids have mostly dried up. Now we get fentanyl and fentanyl analogs, and other potent synthetic opioids that aren't well tracked. The reason is that it's extremely potent so it's easier to smuggle from China, Mexico, wherever it's being made. So now you get "pressies" [homemade pressed pills] which is diluted fentany…
Would this be solved by legalizing and regulating opiates?