The advice here is to sit for 20-30 minutes at a time and then take a 2-minute walking break. This sort of schedule happens to correspond nicely with the Pomodoro Technique, which suggests 25 minutes of work followed by 5-minute breaks. http://en.wikipedia.org/wiki/Pomodoro_Technique
Moving around is really, really the best thing to do in a Pomodoro break. Every time I check Facebook or mail instead I regret it.
The downside is, I never figured out how to apply Pomodoro to research work or other stuff that has no discernible tasks - just feels weird then :(