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Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

fiercebiotech.com

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Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#31

Post by max-ibel »

KMnO4 wrote: post #28
monkey88 wrote: post #26

Can't wait until it is bought by an existing company and then discarded, like its previous competitors.

Test strips are $1 x 5 times per day x 30M diabetic Americans. How can this even compete? You can’t sell RF “per-use”.

CVS sells their strips at $0.20 once you buy 200+. I'm sure you can get lower.

And why shouldn't this compete ? Their costs will be lower than test strips, their profits could be very significant.

They probably monetize with the device itself and then a monthly subscription for their tracking portal. Sounds quite reasonable to me. As a patient, I'd love it.

Edit: As a startup, it's not your job to match existing offerings - it's to disrupt. Ask Space-X, they can't compete with Boeing either ;)

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#32

Post by jimrandomh »

jcims wrote: post #8
tempdiabetic wrote: post #6

Earlier quoted context omitted.

The Dexcom G6 is the best CGM on the market, but its sensor filtering (Kalman or particle?) has smoothness and/or continuity priors that cause persistent inaccuracies. I observe these persistent inaccurate states on the fifth or sixth day using a sensor. Calibration doesn't help. The reading goes wrong and stays wrong. It probably happens to you, too, but anyone who doesn't test with a glucometer will likely not noti…

Is there a good source for info on ketogenic diets for type 1 diabetics? My youngest has been on pump therapy for the past 5 years and is completely burnt out from all of the alerts and scares (some of it is self inflicted). She was on a medtronic closed loop system for 4 years and that was the source of most of her frustration. She's on g6+tslim now which has been much better, but she still falls off the wagon regul…

T1 here. I use OpenAPS with a G6 for closed looping (it's substantially better than Medtronic's looping algorithm), combined with a keto diet. The keto diet makes things a lot easier; there's no carb entry to do, so no opportunities for mistakes. I would indeed recommend it. Just make sure to count calories (at least initially) and keep them high enough; most people on keto diets are using them for weight loss, and that style of keto diet isn't sustainable.

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#33

Post by markh »

jcims wrote: post #8
tempdiabetic wrote: post #6

Earlier quoted context omitted.

The Dexcom G6 is the best CGM on the market, but its sensor filtering (Kalman or particle?) has smoothness and/or continuity priors that cause persistent inaccuracies. I observe these persistent inaccurate states on the fifth or sixth day using a sensor. Calibration doesn't help. The reading goes wrong and stays wrong. It probably happens to you, too, but anyone who doesn't test with a glucometer will likely not noti…

Is there a good source for info on ketogenic diets for type 1 diabetics? My youngest has been on pump therapy for the past 5 years and is completely burnt out from all of the alerts and scares (some of it is self inflicted). She was on a medtronic closed loop system for 4 years and that was the source of most of her frustration. She's on g6+tslim now which has been much better, but she still falls off the wagon regul…

This book might be of interest:

Dr. Bernstein's Diabetes Solution: The Complete Guide to Achieving Normal Blood Sugars

It’s comprehensive and goes into the why and how, which is not to say it’s easy to do.

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#34

Post by LegitShady »

DougWebb wrote: post #27
jcims wrote: post #8

Earlier quoted context omitted.

Is there a good source for info on ketogenic diets for type 1 diabetics? My youngest has been on pump therapy for the past 5 years and is completely burnt out from all of the alerts and scares (some of it is self inflicted). She was on a medtronic closed loop system for 4 years and that was the source of most of her frustration. She's on g6+tslim now which has been much better, but she still falls off the wagon regul…

I'd recommend watching Dr Sten Eckberg's videos, like this one: https://youtu.be/XTmUnIrmAe8 I'm on a keto diet for chronic insulin resistance and obesity, caused by 50 years of high carb eating. (Every meal a sandwich, or including potatoes or rice, and lots of sugar.) I got a CGM a few months ago to help me directly see the impact of the foods I'm eating. It has allowed me to fine tune my diet and get rid of everyt…

so what foods did you cut out, and what foods do you regularly eat?

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#35

Post by [deleted] »

idealmedtech wrote: post #23
tempdiabetic wrote: post #6

Earlier quoted context omitted.

The Dexcom G6 is the best CGM on the market, but its sensor filtering (Kalman or particle?) has smoothness and/or continuity priors that cause persistent inaccuracies. I observe these persistent inaccurate states on the fifth or sixth day using a sensor. Calibration doesn't help. The reading goes wrong and stays wrong. It probably happens to you, too, but anyone who doesn't test with a glucometer will likely not noti…

I've done accuracy studies of the G6 for a submission to the FDA, and while it's true they do filter out spikes, they're never more than 5mg/dL off from the measured value (which itself is usually within 10% of the real value). Interstitial lags are closer to 5 minutes when you're not experiencing severe perfusion issues, which is more than close enough for making dosing decision, especially considering subcutaneous…

[deleted]

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#36

Post by bdcravens »

"...the radiofrequency sensor technology was able to measure glucose levels with accuracy comparable to that of Abbott’s Freestyle Libre continuous glucose monitor..."

Then this means it won't eliminate fingersticks 100%. I've never used the Libre, but I use Medtronic's Guardian sensor, which requires calibration twice a day via fingersticks.

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#37

Post by DougWebb »

LegitShady wrote: post #34
DougWebb wrote: post #27

Earlier quoted context omitted.

I'd recommend watching Dr Sten Eckberg's videos, like this one: https://youtu.be/XTmUnIrmAe8 I'm on a keto diet for chronic insulin resistance and obesity, caused by 50 years of high carb eating. (Every meal a sandwich, or including potatoes or rice, and lots of sugar.) I got a CGM a few months ago to help me directly see the impact of the foods I'm eating. It has allowed me to fine tune my diet and get rid of everyt…

so what foods did you cut out, and what foods do you regularly eat?

Everybody's body responds differently, so you have to experiment to see what works for you. The CGM has been a great tool for that. I also use a Keto-Mojo for blood glucose and ketone testing now and then.

What's worked for me is a diet of eggs, cheese, bacon, chicken, ground beef, ground pork, roast beef, turkey, pepperoni, kale, cabbage, Brussels sprouts, coffee, seltzer, bone broth, half & half, heavy cream, rebel ice cream (but not other keto ice cream brands), almond flour, ground pork rinds (as a bread crumb substitute), and probably some more I'm forgetting.

Typical advice is to stay under 20g net carbs, but I've found that I do better if I count total carbs instead for any non-veggie foods. Keto-friendly substitutes for flour and sugar mess me up most of the time, but I've found a few things that are ok. I also do intermittent fasting, only eating one or two meals during a 6-8 hour window, but I do much better if I fast for 36-48 hours. Dr Eckberg has some good videos on why fasting that long makes a difference.

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#38

Post by RHSeeger »

tempdiabetic wrote: post #21
RHSeeger wrote: post #18

Earlier quoted context omitted.

I can't say enough good things about my G6. It literally changed my life as far as how I interact with my diabetes. - I feel safer when I go to bed, because it's there to wake me up if my blood gets low (or too high). - I feel safer in general because I don't need to worry that my blood is low but I haven't noticed it; and that I'm going to just fall down face first while walking across the room. - Testing my blood i…

If I may ask, what's your HbA1c, and please be honest?

Summer 2021 - 6.7

Winter 2020 - 6.2

Summer 2020 - 5.7

Winter 2020 - 6.6

Fall 2019 - 6.0

My numbers tend to range in the high 5s to low 6s. That being said, the past two years have been rough because of a thyroid issue, plus 2 different drugs that impact blood sugar a lot (my blood sugar was hovering around 180 all day today, having not eaten since last night, and taking 80 units of short acting insulin over 4 shots... its been pretty crazy)

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#39

Post by DougWebb »

jimrandomh wrote: post #32
jcims wrote: post #8

Earlier quoted context omitted.

Is there a good source for info on ketogenic diets for type 1 diabetics? My youngest has been on pump therapy for the past 5 years and is completely burnt out from all of the alerts and scares (some of it is self inflicted). She was on a medtronic closed loop system for 4 years and that was the source of most of her frustration. She's on g6+tslim now which has been much better, but she still falls off the wagon regul…

T1 here. I use OpenAPS with a G6 for closed looping (it's substantially better than Medtronic's looping algorithm), combined with a keto diet. The keto diet makes things a lot easier; there's no carb entry to do, so no opportunities for mistakes. I would indeed recommend it. Just make sure to count calories (at least initially) and keep them high enough; most people on keto diets are using them for weight loss, and t…

Well, once you've finished "eating" your body fat, you can't sustain the calorie restriction. But at that point there's no reason too. For those of us prone to insulin resistance, we have to continue to eat low-carb to avoid putting the weight back on. (Very similar to how an alcoholic who's gotten sober has to continue to avoid alcohol.) But we don't need to have a caloric deficit anymore.

Re: Know Labs unveils glucose monitor that swaps fingersticks for RF sensors

#40

Post by gremloni »

wincy wrote: post #12
1123581321 wrote: post #11

Earlier quoted context omitted.

Patients averse to finger sticks are going to use this much more often. It's going to provide more useful data to them. Much of the time the exact number isn't as important as knowing the trend or the general range. Whether this makes more sense than a Libre for someone just depends on price and how insurance treats it.

I tested my blood sugar when my wife was pregnant and she was testing hers. I was amazed at how just from the small blood stick, and even if I had my wife do it and didn’t see any blood, I’d get sick to my stomach every time I did a blood stick. I’m glad I don’t have diabetes or I’d have a terrible time of it.

Then do it till you get over it. You’re just so comfortable being a pansy, it disgusts me.
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