Anti-Aging: State of the Art

Could you please provide some evidence for how these impact longevity? Especially those from natural sources, e.g. stevia and monk fruit. Not trying to be snarky, just genuinely curious!

I'm reading through Sinclair's book "Lifespan - Why We Age and Why We Don’t Have To" and I find it fascinating (especially the chapter on origins of life and proto-genes of aging). When Sinclair talks about time-scales, he makes comparison to cancer. During last 50 years medicine went from fighting symptoms to actually addressing source for some cancer types. The quote that stood out: "From looks of it aging is not going to be that hard to treat, far easier than curing cancer". Book's predictions may feel too optimistic to me, but I don't have any qualifications to make such claim against leading researcher in field.

There is too much to say..but short version: Cryonics was not just bad science. It was considered by many of us then as bad science fiction...at its best. At its worst, no more useful than the Egyptian mummification attempts to become immortal. In the end, the Egyptian mummies ended to as fertilizer anyways.

Alcor that went by Life Extension then got into a right royal soup later when Ted Williams frozen body was separated from his head that went missing and was kicked around by a rogue employee. Several of his DNA samples went missing.

It was GNARLY. I slowly became disenchanted but I have to admit that reading this now, great strides have certainly been made..not so much as getting closer to anti-ageing, but more in terms of clarity of purpose.

On a slightly related(nostalgic) note: ‘neural link’ was always the reachable and desirable goal. And I think that’s where we will end up eventually. Neural links and clones/bionic/prosthetic aided clones.

Re: Ted Williams and Alcor .. https://connectingdirectors.com/53931-ted-williams

[..]But the worst was yet to come. Fast forward seven years to 2009, when a book by a former employee of Alcor hit the shelves containing explosive allegations of Alcor’s abusive treatment of Williams’ frozen head. Author Larry Johnson wrote that an empty tuna can was used as a pedestal to support the slugger’s head while experiments (which subsequently cracked his frozen brain) were conducted. When the tuna can became stuck to the head, an Alcor employee allegedly tried to dislodge it by swinging at it with a monkey wrench, in the process missing the can and connecting with Williams’ head instead. Johnson wrote that the impact sprayed “bits of frozen head” around the room.[..]

One of the crudest forms of medicine is dentistry. It’s a very brute force method of replacing lost parts. Teeth are the extension of our bodies and it’s connected to every aspect of life.

It’s similar to a living organ and is the sum total of our health. And what do we do with tooth loss? We replace it cosmetically and functionally.

We don’t see any other use for it. If we consider teeth regeneration like growing ourselves a kidney instead of a kidney transplant.(or heart), that would be the day anti ageing is in our sights.

But we have to first consider the problem and label it properly. It is known that plaque in teeth is indicative of heart plaque. Dental infections can get into the blood stream. Cavities point to other issues too. Dental health starts with gum health.

And yet..the remedy is not changing life style or eating habits or research into rejuvenation. But we knock them out and stick a ceramic one. Imagine if we stuck a silicone heart or a kidney like one would a breast implant. That’s the equivalent of fake teeth that is drilled and screwed to the jaw bone.

If we figure out how to regrow our teeth, half the battle is won.