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How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

pubmed.ncbi.nlm.nih.gov

31–40 of 149 posts

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#32
I had a mini-episode of this earlier this year. Reposting as a warning for people:

I had mild Vitamin D deficiency which was diagnosed by a doctor many years ago. I was given Vitamin D supplements, which I stocked up on more than usual recently due to my staying in all day due to WFH and not getting any sunlight.

I used to take 50mcg of D3 1-2x a week and I upped that (without consulting a doctor) to 5x a week. Within two weeks, I started having extreme thirst. It was crazy to the point where I drank so much water that I could hear it sloshing in my stomach yet my mouth was parched dry and I was still very thirsty.

I did a quick Google search and found that Vitamin D poisoning was actually a thing [0]. I stopped my Vitamin D supplements the next day and my thirst went away that same day. Be careful folks.

[0] https://www.express.co.uk/life-style/health/1203879/vitamin-...

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#33

The title doesn’t match the abstract. This isn’t a study of the tolerable upper limit of Vitamin D intake. It’s a case report of a single individual who was taking astronomical doses of Vitamin D with disastrous consequences. It’s certainly possible to take too much vitamin D without coming anywhere near the silly doses this person was consuming. Anyone taking aggressive vitamin D doses should invest in a vitamin D t…

Megadosing B12 (if your diet isn't already sufficient in it, which is common amongst certain vegan diets) is still a good idea, no? I recognize this might be the only exception.

I don't see any evidence that it's a bad idea, but from poking around I get the feeling that there is still a lot about it that we don't know.

For instance, it may be monkeying around with blood flow to the kidneys somehow.

"Among patients with diabetic nephropathy, high doses of B vitamins compared with placebo resulted in a greater decrease in GFR and an increase in vascular events."

https://jamanetwork.com/journals/jama/fullarticle/185758

House AA, Eliasziw M, Cattran DC, et al. Effect of B-Vitamin Therapy on Progression of Diabetic Nephropathy: A Randomized Controlled Trial. JAMA. 2010;303(16):1603–1609. doi:10.1001/jama.2010.490

So, it's probably fine, but honestly nobody really knows.

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#34

The title doesn’t match the abstract. This isn’t a study of the tolerable upper limit of Vitamin D intake. It’s a case report of a single individual who was taking astronomical doses of Vitamin D with disastrous consequences. It’s certainly possible to take too much vitamin D without coming anywhere near the silly doses this person was consuming. Anyone taking aggressive vitamin D doses should invest in a vitamin D t…

Megadosing B12 (if your diet isn't already sufficient in it, which is common amongst certain vegan diets) is still a good idea, no? I recognize this might be the only exception.

"megadosing" doesn't sound like its required for any reason unless you're malnourished, in which case your doctor would tell you how much to take. Adjusting your diet to not require "megadosing" due to malnourishment sounds like a better plan for long term health.

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#35
post #32

I had a mini-episode of this earlier this year. Reposting as a warning for people: I had mild Vitamin D deficiency which was diagnosed by a doctor many years ago. I was given Vitamin D supplements, which I stocked up on more than usual recently due to my staying in all day due to WFH and not getting any sunlight. I used to take 50mcg of D3 1-2x a week and I upped that (without consulting a doctor) to 5x a week. Withi…

how much is 50mcg in IU?

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#36
post #15

On this page it says the recommended dosage is 600 IU https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessiona... Are there any other opinions?

My doc has had me taking 15,000 IU for four years or so. So, some other opinions.

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#37
If you're interested in looking up more info, the medical term for this is "hypervitaminosis"[1], and is most common with fat soluble vitamins A and D since those can build up in the body more easily than water soluble vitamins.

[1] https://en.wikipedia.org/wiki/Hypervitaminosis

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#38
post #32

I had a mini-episode of this earlier this year. Reposting as a warning for people: I had mild Vitamin D deficiency which was diagnosed by a doctor many years ago. I was given Vitamin D supplements, which I stocked up on more than usual recently due to my staying in all day due to WFH and not getting any sunlight. I used to take 50mcg of D3 1-2x a week and I upped that (without consulting a doctor) to 5x a week. Withi…

how much is 50mcg in IU?

"One International Unit (IU) equals 0.025 mcg of cholecalciferol (Vitamin D3) or of ergocalciferol (Vitamin D2)" [1]

[1] https://walrus.com/questions/converting-units-iu-of-vitamin-...

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#39
post #6

Taking 130,000UI per day for 20 months is insane. Most of the over the counter doses are ~ 5000UI. I'm curious, as to what was the patients diet like? Vit D is a fat soluble vitamin and its my understanding that one needs to eat healthy fats for it to be absorbed by the body.

most of the supplements I've seen here are 1000ui, meaning she'd have to take 130 of the pills.

It makes more sense when you realize there are liquid forms of d3 you can buy which probably make it much easier to dose really high.

Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

#40
post #38

Earlier quoted context omitted.

how much is 50mcg in IU?

"One International Unit (IU) equals 0.025 mcg of cholecalciferol (Vitamin D3) or of ergocalciferol (Vitamin D2)" [1] [1] https://walrus.com/questions/converting-units-iu-of-vitamin-...

Hmm, so 2000IU. That doesn’t seem like a lot, but I guess it really depends on the person.
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