How can you do science for long term effects?
where RCTs are not possible.
Vitamin D: the New Covid-19 Chloroquine?
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Re: Vitamin D: the New Covid-19 Chloroquine?
#32Since I was a child I’ve been a walking respiratory illness machine. Bronchitis, sinusitis, flu, pneumonia, common cold, etc. During “flu” season I was usually sick for the entire season with a rotating assortment of viral respiratory issues, this lasted until about 7 years ago. 8 years ago in September I started taking 10,000 IU of vitamin D3 and 180mg of K2 daily. I haven’t had a deputies illness since. My children…
I switched to a high cholesterol diet. Almost only meat , raw milk(grass fed) and raw egg yolks (monthly liver) combined with 20 minutes of running shirtless. Besides getting very lean I’ve also not been sick once during this. I usually get sick all the time. It’s antidotal but my diet would now be really high in k2 vitamin A and natural Vitamin D
Re: Vitamin D: the New Covid-19 Chloroquine?
#33How can you do science for long term effects? where RCTs are not possible.
When I took an epidemiology course in college, our professors taught us about both control studies and cohort studies. Cohort studies might be an example of what you're looking for. This article [0] hosted on the NIH's site discusses cohort studies and their effectiveness / pitfalls.
References: [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998589/
Re: Vitamin D: the New Covid-19 Chloroquine?
#34This requires a huge correlation != causation flag.
The article briefly mentions this, noting that it’s possible vitamin D is just a sign of a healthy person, so of course they’ll do better with COVID. Another correlation that doesn’t get discussed whenever vitamin D comes up is that people with darker skin generally have less vitamin D, because our skin doesn’t absorb sunlight as much. We also know that COVID is disproportionately hitting colored neighborhoods in the US. Is that just because of vitamin D differences? Who knows!
By the way, if you are a person of color, you probably need vitamin D supplements. The recommended doses are for white people, so adjust accordingly.
Re: Vitamin D: the New Covid-19 Chloroquine?
#35Since I was a child I’ve been a walking respiratory illness machine. Bronchitis, sinusitis, flu, pneumonia, common cold, etc. During “flu” season I was usually sick for the entire season with a rotating assortment of viral respiratory issues, this lasted until about 7 years ago. 8 years ago in September I started taking 10,000 IU of vitamin D3 and 180mg of K2 daily. I haven’t had a deputies illness since. My children…
Can't you take less D3 daily to prevent calcification? 10k IU sounds like a large amount, no?
Re: Vitamin D: the New Covid-19 Chloroquine?
#36Earlier quoted context omitted.
We have multiple vaccine candidates that based on early human trials, and animal trials are very likely to work. Sure it's possible all of them could fail, but I wouldn't set my bet on that.
Right. There are around 100 vaccines in development. We have vaccines that have created binding antibodies in primates already. We have some that have been given to humans and produced antibodies as well. Even pessimistically assuming 90% fail, you end up with 10 vaccines. https://www.centerwatch.com/articles/12702-new-mit-study-put...
that's not pessimistic.
Regularly only 6% of vaccines make it past trials.
Re: Vitamin D: the New Covid-19 Chloroquine?
#37For me this is a perfect example of wishful thinking. It's really hard for average person to accept reality: This virus, like all others, will last for a long time. We won't have, in a foreseeable future, a treatment neither a cure. Cancer, HIV or even seasonal flue are good examples examples of diseases that were discovered decades ago for which science still don't have a cure, there are a few treatments or easing m…
We have extremely good treatments for HIV. And that one is particularly difficult to cure because it infects your immune system.
Cancer isn't an infection and is a million different diseases lumped together.
We could prevent the flu much more reliably if it didn't mutate so much. Will this disease do the same? Maybe. It's very hard to know.
Re: Vitamin D: the New Covid-19 Chloroquine?
#38All these articles about different individual nutrients start to feel like heath whack-a-mole. How about this: to be in the best possible position to beat any serious infection, you need to be in generally good health. That means having adequate levels of all essential nutrients - i.e., all the vitamins, minerals, amino acids, enzymes etc that you get from maintaining a good diet and healthy lifestyle over the long t…
And, try to get those things from foods. It can't be said enough: Fruits and Vegetables have extremely high densities of all your minerals and vitamins. I've calculated all their densities here based on USDA nutritional info: https://kale.world/c All the results are normalized to 200 calories for easy comparison.
When you get your vitamins/minerals from a pill, you run the risk of your body not absorbing it because that's not how our bodies adapted to absorb those things for millions of years.
If you're eating a healthy diet (90%+ plant based whole foods), you will get more than enough minerals/vitamins and amino acids.
Taking a few spoon fulls of hemp seeds is an excellent idea: it's super high in magnesium which is a mineral that most of us are greatly lacking. But, I would consider hemp seeds as just another food part of a plant based whole foods diet. personally, i add it to salads, smoothies, etc.
And you don't need Vitamin K supplements. Greens are extraordinarily high in Vitamin K. Even, just 20 calories of Spinach will provide over 400% of your daily Vitamin K intake!
People, be especially careful with supplements, they're very much unregulated and can put almost anything they want in those things.
Nature makes the best supplements: it's called food (plant based whole foods with a variety of grains and beans, lots of vegetables and fruits and some meat) and it has everything our body needs. Yes, for vitamin D, you'll need to go outside and get some exposure to the sun. Actually, doctor's tell us, Vitamin D isn't even a Vitamin, it's actually a hormone that your body makes all on it's own with enough exposure to sun. But, based on your skin pigmentation, you may need more or less exposure.
Re: Vitamin D: the New Covid-19 Chloroquine?
#39I'm surprised the article barely mentions Vitamin K, which is needed along with Vitamin D - D to mobilize the calcium and K2 to put it into the right place. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/
There is another important pair, too: Vitamin D and Magnesium. But consult your doctor before taking extra amounts of anything. There is a lot of misinformation on the web around Vitamin D, such as that even high amounts (>= 5000IU) are tolerable and safe. After a blood test showed me Vitamin D deficient, taking 5000IU (that size is readily available over the counter at my grocery store) daily gave me disturbing hear…
These units seem _incredibly_ low to me. Your skin can generate almost 3000 IU in just 15 minutes on the right day. Many doctors even recommend treatments of 150,000 IU or more, in one go to correct deficiencies (do not do attempt without a doctor's recommendation and supervision).
I do not doubt your experience, but it seems incredible to me that just a 5000 IU supplement gave you heart palpitations. Then again, I've also read many reports about incorrectly labeled products (e.g. milk, supplements, etc.) which contained far more D2 or D3 than what was written on the tin, causing toxicity.
Re: Vitamin D: the New Covid-19 Chloroquine?
#40Since I was a child I’ve been a walking respiratory illness machine. Bronchitis, sinusitis, flu, pneumonia, common cold, etc. During “flu” season I was usually sick for the entire season with a rotating assortment of viral respiratory issues, this lasted until about 7 years ago. 8 years ago in September I started taking 10,000 IU of vitamin D3 and 180mg of K2 daily. I haven’t had a deputies illness since. My children…
Can't you take less D3 daily to prevent calcification? 10k IU sounds like a large amount, no?
As the article says, D works with other vitamins to do a lot of things. It works with K to help calcium get into your bones. Otherwise you can absorb it and it can hang around in places it's not really supposed to, and that turns out to not be a good thing. You're probably better off with D + K (if you need it) than trying to skimp on D.
(I have celiac [1], and I had to learn about this connection the hard way. The horrid thing is that my normal daily lunch was an enormous bowl of leafy greens, exactly where you're supposed to get vitamin K from, and I still had to supplement it. Calcium in the wrong places was one of the contributing factors to my heart issues in the link. I still have to be a bit careful not to eat too much hard cheese, but only slightly more careful than a normal person who faces potentially blocking themselves up anyhow.)