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Psilocybin found safe for consumption in largest ever controlled study

independent.co.uk

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Re: Psilocybin found safe for consumption in largest ever controlled study

#31

Post by yellow_lead »

kasperni wrote: post #12

Now that mainstream club drugs such as MDMA, Ketamine, and LSD/Magic Mushrooms are finding their way into therapeutic usage. I'm wondering if and how governments will change the current narrative about "all drugs are bad for you". Edit: I'm not advocating recreational drug usage. Just saying, that if mum is on magic mushrooms and studies like these have established safety dosage and clear therapeutic benefits. You ca…

After Snowden's revelations, I also wondered if the government would change it's practices.

Re: Psilocybin found safe for consumption in largest ever controlled study

#32

Post by derefr »

arkades wrote: post #8

This is NOT a trial that was designed to assess the safety of psilocybin. This was a trial meant to show that a particular dosage of psilocybin is /safe enough/ to pursue further research in that dose range. This was a /phase one/ clinical trial. Phase One: administer small doses under very close supervision in a tiny number of people to determine whether it's immediately dangerous, or safe enough /for further study/…

Still big news that anyone is even doing phase 1 trials, since you wouldn't tend to bother if you didn't intend to follow up with further phases. I.e. "X is safe in a phase 1 trial" is never a useful terminal fact that you set out to prove and then, having proven it, do nothing more.

Re: Psilocybin found safe for consumption in largest ever controlled study

#34

Post by vmchale »

ergothus wrote: post #6
sawyerjhood wrote: post #2

I'm personally excited to see what sorts of new treatments will come out of using psychedelics medically. I've always been on the skeptical side of medical marijuana usage in all but the most extreme cases, but I have a feeling that LSD and psilocybin can really provide mental turning points and help people break out of depression.

> I've always been on the skeptical side of medical marijuana usage in all but the most extreme cases, Really? I've always found the milder claims fairly believable (fighting nausea or chronic low level pain relief). As an anecdote, I can attest to dealing with kidney stone pain well (rather than stopping the pain it reduced how much I noticed it) and it ended up more effective and felt less dangerous than the opiods…

There are other anti-nausea drugs lol.

Maybe it's useful if nothing else works but come on.

Re: Psilocybin found safe for consumption in largest ever controlled study

#35

Post by mothsonasloth »

ianai wrote: post #21
mothsonasloth wrote: post #17

I'm gonna sound really cliched but I have become really fascinated with Psychedelics thanks to the Joe Rogan podcast. I wouldn't say I am depressed but as someone who doesn't drink, smoke, drugs or take caffeine. I really want to try them. The fact that mushrooms have been used by shamans all around the world since neolithic times, is truly fascinating. I hope to try them at some point although at the moment I have b…

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

After googling, it appears that kava causes liver damage, thanks but no thanks

Re: Psilocybin found safe for consumption in largest ever controlled study

#36

Post by ianai »

r00fus wrote: post #25
ianai wrote: post #21

Earlier quoted context omitted.

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

What source would you recommend? I've tried some name-brand kava tea and it didn't seem to do much.

I’ve had extracts that didn’t do much. Pills of the powder have helped. The biggest experience I had was with the full on blending of the powder in a blender following a YouTube recipe video-wakacon from amazon.

Re: Psilocybin found safe for consumption in largest ever controlled study

#37

Post by dmurray »

arkades wrote: post #8

This is NOT a trial that was designed to assess the safety of psilocybin. This was a trial meant to show that a particular dosage of psilocybin is /safe enough/ to pursue further research in that dose range. This was a /phase one/ clinical trial. Phase One: administer small doses under very close supervision in a tiny number of people to determine whether it's immediately dangerous, or safe enough /for further study/…

Are controlled experiments necessary for proving safety? Intuitively, there shouldn't be a placebo effect, and you could get twice as powerful a study by giving twice as many people the drug and using statistics for the general population as the control group.

Re: Psilocybin found safe for consumption in largest ever controlled study

#38

Post by JumpCrisscross »

kasperni wrote: post #12

Now that mainstream club drugs such as MDMA, Ketamine, and LSD/Magic Mushrooms are finding their way into therapeutic usage. I'm wondering if and how governments will change the current narrative about "all drugs are bad for you". Edit: I'm not advocating recreational drug usage. Just saying, that if mum is on magic mushrooms and studies like these have established safety dosage and clear therapeutic benefits. You ca…

> I'm wondering if and how governments will change the current narrative about "all drugs are bad for you".

Caffeine and alcohol are "drugs". But they aren't drugs. In the same way, I think we'll the label released from accepted substances, while remaining attached to unacceptable ones.

Re: Psilocybin found safe for consumption in largest ever controlled study

#40

Post by LinuxBender »

ianai wrote: post #21
mothsonasloth wrote: post #17

I'm gonna sound really cliched but I have become really fascinated with Psychedelics thanks to the Joe Rogan podcast. I wouldn't say I am depressed but as someone who doesn't drink, smoke, drugs or take caffeine. I really want to try them. The fact that mushrooms have been used by shamans all around the world since neolithic times, is truly fascinating. I hope to try them at some point although at the moment I have b…

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

I would add in the non essential amino acid L-Theanine [1]. Has a nice calming and focusing effect.

[1] - https://examine.com/supplements/theanine/

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