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Study Linking Autism to 'Male Brain' Retracted, Replaced

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Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#32
post #21
post #13

Earlier quoted context omitted.

No, it's a victory for all the women who are autistic but go years without a diagnosis because of stereotypes about autism. Simon Baren Cohen is an expert, but he's got some stuff badly wrong before, such as saying that autism is a condition marked by lack of empathy because of alexithymia. Turns out this is incorrect, but it caused considerable hardship for many autistic people who were unable to get a dx because th…

How does a diagnosis benefit someone with autism?

The same way a diagnosis benefits anyone who requires medical treatment.

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#33
post #2

A quick look at Simon Baron Cohen's tweet[1] (linked from the article) shows that this topic seems extremely divisive and inflammatory to people. Is this retraction and resulting modified study seen as an important victory for people promoting that there are no differences between the "male" and "female" brains? [1] https://twitter.com/sbaroncohen/status/832490232721371136

It's only a political thing in the minds of the politically-inclined. Since when was autism a cornerstone in anybody's ideology? I think the only reason this is riling people up is that it involves gender in the title.

> Since when was autism a cornerstone in anybody's ideology?

Anti-vaxxers?

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#34
I've been following the field including Simon Baron-Cohen's studies for well over a decade. I have journal access.

There were 16 co-authors [1] to the original article, including Simon Baron-Cohen, Director of the Autism Research Centre (ARC) in Cambridge University [2].

It would seem extraordinary that all of these people including Baron-Cohen would co-sign an article without checking the work. This is especially true given that some people (Emily Willingham, Phd) have a political agenda about the issue.

It seems more likely that there was some political motivation for the withdrawal, despite the "methodology" errors which again 16 co-authors did not catch, including Baron-Cohen.

I wonder how we can believe any article in JAMA Psychiatry if they let a political agenda get in the way of true science. One must consider the real possibility that the primary author had their career threatened if their article was not withdrawn.

What is required is that all source material and analysis be put on-line for anyone to be able to replicate the study (or the study mistake). That is the only way for JAMA Psychiatry to clear itself of accusations of bending to politics.

[1] Christine Ecker, PhD1,2; Derek S. Andrews, MSc2; Christina M. Gudbrandsen, MSc2; Andre F. Marquand, PhD3,4; Cedric E. Ginestet, PhD5; Eileen M. Daly, PhD2; Clodagh M. Murphy, PhD2,6; Meng-Chuan Lai, PhD7,8,9; Michael V. Lombardo, PhD7,10; Amber N. V. Ruigrok, PhD7; Edward T. Bullmore, PhD, FRCPsych11; John Suckling, PhD11; Steven C. R. Williams, PhD4; Simon Baron-Cohen, PhD7; Michael C. Craig, PhD2,12; Declan G. M. Murphy, FRCPsych2,6; for the Medical Research Council Autism Imaging Multicentre Study (MRC AIMS) Consortium

[2] https://www.autismresearchcentre.com/people_Baron-Cohen

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#35
post #21

Earlier quoted context omitted.

How does a diagnosis benefit someone with autism?

Early intervention with behaviour modification therapy, especially in early school life where social interaction skills really matter. In adult life, it can lead to better psychological therapy. Managing anxiety in ASD is different to neurotypical people, for example.

> Managing anxiety in ASD is different to neurotypical people, for example.

Speaking as somebody too 'high functioning' for a diagnosis... please elaborate

edit: the responses to this feel weird, does anybody have resources for ASD folks experiencing anxiety?

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#36
post #2

A quick look at Simon Baron Cohen's tweet[1] (linked from the article) shows that this topic seems extremely divisive and inflammatory to people. Is this retraction and resulting modified study seen as an important victory for people promoting that there are no differences between the "male" and "female" brains? [1] https://twitter.com/sbaroncohen/status/832490232721371136

It's only a political thing in the minds of the politically-inclined. Since when was autism a cornerstone in anybody's ideology? I think the only reason this is riling people up is that it involves gender in the title.

"Men have different distribution of extremes, more dumbasses but also more brilliance, eg. autistic savants, which explains more CEOs and Nobel Prize winners, and therefore systemic sexism is a myth to deny biologically determined outcomes."

it's a very important shibboleth for modern sexists

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#37
post #12

Looks like it was an issue with a script. I wouldn't be surprised if this isn't a bigger issue than we know in science. Good scripting practice is not taught in most programs. On top of that it's not really possible to write tests for regressions.

What would a good resource for good scripting practices?

I would like to second this question.

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#38
post #35

Earlier quoted context omitted.

Early intervention with behaviour modification therapy, especially in early school life where social interaction skills really matter. In adult life, it can lead to better psychological therapy. Managing anxiety in ASD is different to neurotypical people, for example.

> Managing anxiety in ASD is different to neurotypical people, for example. Speaking as somebody too 'high functioning' for a diagnosis... please elaborate edit: the responses to this feel weird, does anybody have resources for ASD folks experiencing anxiety?

Well for one stressors are different - in addition to sensory issues that aren't common things like not finding awkward silences awkward. Stimming probably wouldn't prove helpful to neurotypicals for an example backwards.

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#39
post #35

Earlier quoted context omitted.

Early intervention with behaviour modification therapy, especially in early school life where social interaction skills really matter. In adult life, it can lead to better psychological therapy. Managing anxiety in ASD is different to neurotypical people, for example.

> Managing anxiety in ASD is different to neurotypical people, for example. Speaking as somebody too 'high functioning' for a diagnosis... please elaborate edit: the responses to this feel weird, does anybody have resources for ASD folks experiencing anxiety?

For one thing, anxiety isn't always a root cause. If you are autistic your anxiety may have roots in sensory issues, different from anxiety experienced by someone with schizophrenia.

Re: Study Linking Autism to 'Male Brain' Retracted, Replaced

#40
post #16
post #2

A quick look at Simon Baron Cohen's tweet[1] (linked from the article) shows that this topic seems extremely divisive and inflammatory to people. Is this retraction and resulting modified study seen as an important victory for people promoting that there are no differences between the "male" and "female" brains? [1] https://twitter.com/sbaroncohen/status/832490232721371136

Yes. Not related to this specific study: > Meet the neuroscientist shattering the myth of the gendered brain > Are there any significant differences based on sex alone? The answer, she says, is no. To suggest otherwise is “neurofoolishness”. https://www.theguardian.com/science/2019/feb/24/meet-the-neu...

She's mincing words, by overemphasizing a distinction between that "highly correlated" isn't that same as "completely explained by". It's akin to saying "There are no significant differences in height based on sex alone, since some women are taller than some men."
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