Gut microbes are vulnerable to wide range of drugs • Hacker News Board

Re: Gut microbes are vulnerable to wide range of drugs

#31

Post by bfuller » Mon, Apr 09, 2018, 3:49 PM UTC

mathattack wrote: post #28

CaliforniaKarl wrote: post #8

Earlier quoted context omitted.

> to put the effect into context I'd be interested in the effect of, for example, normal food. I bet that it's also gonna depend alot on the person, and their history. This has always stuck with me: > After he was fired for incompetence, he took it on himself to sue the restaurant, claiming that his gastrointestinal problem, caused apparently by amoebas, was a result of his work there. Management took this litigation…

How could they force everyone to take that test without it being an invasion of privacy? I’ve seen the symptom first hand in SE Asia. Things that got me sick wouldn’t phase the locals who were used to it.

They can't force you, but if you tell someone their coworker has an amoeba they will want to know if they have it too

Re: Gut microbes are vulnerable to wide range of drugs

#32

Post by slfnflctd » Mon, Apr 09, 2018, 4:02 PM UTC

forgotmypw wrote: post #18

Semirhage wrote: post #2

What I want to know is what to do about it by way of probiotic therapy or buffering agents and such. Efficacy of probiotics in practice seems mixed, so what exactly is the takeaway here for the practically minded person who sometimes takes anti-inflammatory medications?

I think that the best thing one can do for their microbiome is to stop trying to kill germs in everything around us. Also, when a dog wants to kiss you, accept it. They are good at maintaining theirs. Look at the ingredients on all the products you use. Unless it's Dr. Bronner's soap or something similar, chances it's harmful to both humans and microbes. Just stop using and stop buying that shit! Sterility is good fo…

I agree to a point, but a lot of dogs don't get proper dental care, eat poop and lick buttholes-- sorry, but I don't want any of that on my face, I don't care how magical their saliva is supposed to be.

Re: Gut microbes are vulnerable to wide range of drugs

#33

Post by caconym_ » Mon, Apr 09, 2018, 4:58 PM UTC

adrianN wrote: post #24

forgotmypw wrote: post #18

Earlier quoted context omitted.

I think that the best thing one can do for their microbiome is to stop trying to kill germs in everything around us. Also, when a dog wants to kiss you, accept it. They are good at maintaining theirs. Look at the ingredients on all the products you use. Unless it's Dr. Bronner's soap or something similar, chances it's harmful to both humans and microbes. Just stop using and stop buying that shit! Sterility is good fo…

A lot more people used to die of disease before we figured out to wash our hands regularly.

Are mortality rates significantly lower in the modern developed world (I am assuming this is true) because people in general wash their hands more? Is that what you're trying to imply?

I don't buy it. I'd attribute the difference more to technologies like vaccines and antibiotics.

Re: Gut microbes are vulnerable to wide range of drugs

#34

Post by astura » Mon, Apr 09, 2018, 5:08 PM UTC

slfnflctd wrote: post #32

forgotmypw wrote: post #18

Earlier quoted context omitted.

I think that the best thing one can do for their microbiome is to stop trying to kill germs in everything around us. Also, when a dog wants to kiss you, accept it. They are good at maintaining theirs. Look at the ingredients on all the products you use. Unless it's Dr. Bronner's soap or something similar, chances it's harmful to both humans and microbes. Just stop using and stop buying that shit! Sterility is good fo…

I agree to a point, but a lot of dogs don't get proper dental care, eat poop and lick buttholes-- sorry, but I don't want any of that on my face, I don't care how magical their saliva is supposed to be.

Not to mention I find dog slobber to be extremely off-putting for reasons other than germs. Just like I would find it extremely off-putting if someone went up to me with a clean wet washcloth and started rubbing it on me.

Re: Gut microbes are vulnerable to wide range of drugs

#35

Post by adrianN » Mon, Apr 09, 2018, 5:27 PM UTC

caconym_ wrote: post #33

adrianN wrote: post #24

Earlier quoted context omitted.

A lot more people used to die of disease before we figured out to wash our hands regularly.

Are mortality rates significantly lower in the modern developed world (I am assuming this is true) because people in general wash their hands more? Is that what you're trying to imply? I don't buy it. I'd attribute the difference more to technologies like vaccines and antibiotics.

Proper sanitation has saved more lives than vaccines and antibiotics. Check for example this well researched Quora answer: https://www.quora.com/How-much-have-sanitation-vaccination-a...

Re: Gut microbes are vulnerable to wide range of drugs

#36

Post by caconym_ » Mon, Apr 09, 2018, 7:34 PM UTC

adrianN wrote: post #35

caconym_ wrote: post #33

Earlier quoted context omitted.

Are mortality rates significantly lower in the modern developed world (I am assuming this is true) because people in general wash their hands more? Is that what you're trying to imply? I don't buy it. I'd attribute the difference more to technologies like vaccines and antibiotics.

Proper sanitation has saved more lives than vaccines and antibiotics. Check for example this well researched Quora answer: https://www.quora.com/How-much-have-sanitation-vaccination-a...

"Proper sanitation" includes much more than just hand washing (e.g. properly disposing of urine and feces rather than throwing them into the street), so you're refuting a statement that I never made.

If you can disentangle hand washing from the effects of modern sanitation in general, I'm interested to hear more.

Re: Gut microbes are vulnerable to wide range of drugs

#37

Post by forgotmypw » Tue, Apr 10, 2018, 4:21 AM UTC

astura wrote: post #34

slfnflctd wrote: post #32

Earlier quoted context omitted.

I agree to a point, but a lot of dogs don't get proper dental care, eat poop and lick buttholes-- sorry, but I don't want any of that on my face, I don't care how magical their saliva is supposed to be.

Not to mention I find dog slobber to be extremely off-putting for reasons other than germs. Just like I would find it extremely off-putting if someone went up to me with a clean wet washcloth and started rubbing it on me.

This is an indicator of your conditioning.

Re: Gut microbes are vulnerable to wide range of drugs

#38

Post by forgotmypw » Tue, Apr 10, 2018, 4:21 AM UTC

slfnflctd wrote: post #32

forgotmypw wrote: post #18

Earlier quoted context omitted.

I think that the best thing one can do for their microbiome is to stop trying to kill germs in everything around us. Also, when a dog wants to kiss you, accept it. They are good at maintaining theirs. Look at the ingredients on all the products you use. Unless it's Dr. Bronner's soap or something similar, chances it's harmful to both humans and microbes. Just stop using and stop buying that shit! Sterility is good fo…

I agree to a point, but a lot of dogs don't get proper dental care, eat poop and lick buttholes-- sorry, but I don't want any of that on my face, I don't care how magical their saliva is supposed to be.

This is an indicator of your conditioning.