I personally believe that meditation and journeying inward without drugs brings about insights of a similar magnitude in a pace that we can cope with and integrate what we learn without jojo’ing between bliss and depression.
Ayahuasca has its place. It definitely helped us experience that there is much more to life than the material. But in my opinion I t’s a sledge Hammer that helps crack hard nuts or sets a direction. The work has to be done by oneself and the risk with ayahuasca is that one just keeps drinking the tea, thinking that that is enough.
Apart from that it is quite dangerous nowadays to do ceremonies with traveling “shamans”, because a lot of them don’t even brew the tea themselves and oftentimes facilitate in a way that it is bound to go wrong at some point.