TPP felt to me one of the issues that really defined the Trump campaign and the voters it appealed to. I think Clinton eventually [0] took a public stance against the TPP, but ignoring the public's perception of her relation to the truth, she clearly did not prioritize the dismantling of TPP in the way that Trump did. In fact, it's really hard to imagine her undoing President Obama's work were she in office. If someo…
Also, she was not that compelling as a candidate. And had all those negatives that I won't go into. Most of them false. But still, why do you put up a establishment candidate on a change cycle (looking at you Wassermann and Brazille, core dems)?
Edit: I don't especially like TPP but I saw it as a strategic shift to Asia for the US. Now China will likely join a TPP-light and really benefit. For better or worse this is going to be a big change over the next 20 years.