Earlier quoted context omitted.
Easy to test. Get 80% of your calories from fructose syrup. The rest from plant food. Feel free to report in a year.
> Get 80% of your calories from fructose syrup. Pretty sure you would die in less than 38 hours.
A theory on how insulin resistance, metabolic disease begin
31–40 of 56 posts
Re: A theory on how insulin resistance, metabolic disease begin
#32Always gotta come up with a new drug. Why not just eat a diet with no added sugar?
Re: A theory on how insulin resistance, metabolic disease begin
#33Re: A theory on how insulin resistance, metabolic disease begin
#34Earlier quoted context omitted.
From your description of the issue , it seems that DouxMatok's sweeter sugar technology[1] could solve this dillema - by giving the tongue the same sense of sweetness , but in the gut, where sugar dissolves, only 1/2 of the sugar enters. [1]By coating inert mineral particles that have no caloric value with sugar molecules, DouxMatok developed a sugar substitute that (allegedly) tastes just like pure sugar. The sugar-…
The actual problem is that less sugar enters the blood stream than is tasted. The real solutions are really unexciting, like eating fewer sweetened foods, and eating foods sweetened with natural sugar. Honestly, my biggest take away from the research is that there is no substitute for eating healthy. For instance, vitamin supplements don't appear to convey the same health benefits as consuming the vitamins in foods i…
It would be easy to test that real solution by comparing diets from a place where they don't eat as much sugar.
Re: A theory on how insulin resistance, metabolic disease begin
#35Earlier quoted context omitted.
From your description of the issue , it seems that DouxMatok's sweeter sugar technology[1] could solve this dillema - by giving the tongue the same sense of sweetness , but in the gut, where sugar dissolves, only 1/2 of the sugar enters. [1]By coating inert mineral particles that have no caloric value with sugar molecules, DouxMatok developed a sugar substitute that (allegedly) tastes just like pure sugar. The sugar-…
The actual problem is that less sugar enters the blood stream than is tasted. The real solutions are really unexciting, like eating fewer sweetened foods, and eating foods sweetened with natural sugar. Honestly, my biggest take away from the research is that there is no substitute for eating healthy. For instance, vitamin supplements don't appear to convey the same health benefits as consuming the vitamins in foods i…
But tasted where ? do we have any knowledge what happens when the tongue measures one level of sweetness and the gut another ?
And don't the case of the gastric bypass implies that if the gut senses less sugar(either because of less sensors, or because of less sugar) , we get positive results ?
>> no substitute for eating healthy.. than fix through science.
Currently that's good health advice, i agree.
Re: A theory on how insulin resistance, metabolic disease begin
#36Earlier quoted context omitted.
I've never heard of a connection between consuming animal products and diabetes. Perhaps you can expand on this.
I recognize the text pattern from before. Pretty sure I've dealt with this user before, on articles about Diabetes. In the end, it's a whole lot of breathlessness about veganism will "fix diabetes". Of course, no citations, or cited articles that are completely 180deg out of phase. I know what worked for me, was a form of Atkins diet (extremely low carbohydrate diet) backed up with my glucometer. I plot trends of foo…
> The Cause of Insulin Resistance What’s gumming up the door locks on our muscle cells, preventing insulin from letting glucose in? It’s fat. Intramyocellular lipids, or the fat inside our muscle cells.
Yeah. There's something going on with fat. Majorly. I agree with that. And also, whatever it was that was making me crave carbohydrates also made me gain weight like crazy. And you know, when I went on a carb-free (I've also seen research, and talked with researchers who've also discovered that losing as little as 1g of fat on the pancreas can alleviate all symptoms of T2 diabetes. The problem, is there's no known way to target inter-organ fat.
> Fat in the bloodstream can build up inside the muscle cell and create toxic fatty breakdown products and free radicals that can block the insulin signaling process. When that happens, no matter how much insulin we have in our blood, it won’t be able to open the glucose gates. That causes blood sugar levels to build up in the blood.
Then why does doing a low/no carb diet cause us T2 diabetics along with prediabetics to lose weight on a massive scale? It seems to me that there's something wrong with the metabolics/genetics that do something funky to carbohydrates. Something like
Carbohydrates -> sugar -> fat -> stored
And it seems to short circuit what should normally just work.
Source: The article linked in my previous comment. Yes there are sources cited.
Re: A theory on how insulin resistance, metabolic disease begin
#37Earlier quoted context omitted.
The actual problem is that less sugar enters the blood stream than is tasted. The real solutions are really unexciting, like eating fewer sweetened foods, and eating foods sweetened with natural sugar. Honestly, my biggest take away from the research is that there is no substitute for eating healthy. For instance, vitamin supplements don't appear to convey the same health benefits as consuming the vitamins in foods i…
>> The actual problem is that less sugar enters the blood stream than is tasted. But tasted where ? do we have any knowledge what happens when the tongue measures one level of sweetness and the gut another ? And don't the case of the gastric bypass implies that if the gut senses less sugar(either because of less sensors, or because of less sugar) , we get positive results ? >> no substitute for eating healthy.. than…
Given that fact, we can speculate that sweet things that aren't absorbed might be more harmful than ones that are absorbed, as they have a chance to activate taste buds all the way through the gut as they go past, rather than just the earlier ones.
Re: A theory on how insulin resistance, metabolic disease begin
#38Earlier quoted context omitted.
I've never heard of a connection between consuming animal products and diabetes. Perhaps you can expand on this.
I recognize the text pattern from before. Pretty sure I've dealt with this user before, on articles about Diabetes. In the end, it's a whole lot of breathlessness about veganism will "fix diabetes". Of course, no citations, or cited articles that are completely 180deg out of phase. I know what worked for me, was a form of Atkins diet (extremely low carbohydrate diet) backed up with my glucometer. I plot trends of foo…
Still have to analyse/normalize my data, didn't find time yet to build tools for it. Here is just a quick graph where I dumped the numbers into a google spreadsheet:
https://dl.dropboxusercontent.com/u/559047/keto-readings-01....
High glucose implies lower ketones in my case (the correlation is pretty obvious from the plot above). My explanation is that when I get higher glucose in blood, my pancreas increases insulin level and that in turn not only drives glucose down, but also ketones (somehow).
I could be considered a healthy, relative active individual 37yrs, 182cm, 78kg, ~15% BF.
Why I'm posting this here? Eventually I would like to build a tool with a protocol to follow for people who want to follow similar diet and compare their results. I believe this crowd-sourced data could potentially be also an interesting data-set for researchers.
Any hackers interested in building something similar?
Re: A theory on how insulin resistance, metabolic disease begin
#39Earlier quoted context omitted.
The actual problem is that less sugar enters the blood stream than is tasted. The real solutions are really unexciting, like eating fewer sweetened foods, and eating foods sweetened with natural sugar. Honestly, my biggest take away from the research is that there is no substitute for eating healthy. For instance, vitamin supplements don't appear to convey the same health benefits as consuming the vitamins in foods i…
> The real solutions are really unexciting, like eating fewer sweetened foods, and eating foods sweetened with natural sugar. It would be easy to test that real solution by comparing diets from a place where they don't eat as much sugar.
That being said, there is a lot of easy research that never happens. There are a lot of reasons. Funding is difficult to get, and it's hard to get funding to research things that are "obvious". Furthermore, there are a limited number of scientists -- they have to choose what they are going to research.
Re: A theory on how insulin resistance, metabolic disease begin
#40>> If we can develop drugs to target this process, this may be a way to prevent the process early in the development of the disease Always gotta come up with a new drug. Why not just eat a diet with no added sugar?
These pharmaceutical companies are interested in one thing - making money, and therefore they need everyone to be a "customer" by taking one of their pills every day. This means even if there are simple (i.e. non patent-able) solutions to health problems, you won't see them pushing it - instead you'll see them ACTIVELY work to prevent it.
A good example is the recent case where these companies have spent $880 million in the last 10 years working against marijuana legalization, even though studies are showing that it can work as a good pain killer replacement for the more deadly opioids that they are eager to hand out.
See: http://bigstory.ap.org/article/4d69f4b41cbc475ca42f424524003...