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Theranos Has Struggled with Blood Tests

wsj.com

31–40 of 92 posts

Re: Theranos Has Struggled with Blood Tests

#31
post #24

Here's a nice profile from the New Yorker in late 2014: http://www.newyorker.com/magazine/2014/12/15/blood-simpler I mean "nice" as in, a good read...it's a flattering profile of Holmes -- she comes off well, as a genuinely passionate person, and even if she had stayed in school, it sounds like she would've still made a great impact. But the article also raises concerns that seem to be corroborated by the OP: > Clark…

I was helping a friend design a microfluidic device for platelet characterisation, and the first thing he told me was that only a vein was suitable for drawing blood for platelets. He had to take a phlebotomy course just for the blood for testing prototypes.

Re: Theranos Has Struggled with Blood Tests

#32

>>Theranos claims that the usual delay of testing in centralized laboratories is approximately 3 days and that they will generate and deliver their data much faster (e.g., within 4 h). The 3-day delay claim is not accurate. The bulk of laboratory testing in centralized laboratories is completed within an hour or two (calculated from time of sample collection to time of results posting for physician review). For examp…

> This is the same kind of bullshit I see in academia, where a new technology is promised to replace an old technology that works fine, but now they have a 9 billion dollar valuation!

I am not sure it is bullshit, maybe it's just competition?

Over time, companies within an industry become complacent, cut costs, and decrease quality of service. Somebody (a young idealist perhaps?) comes along and says, hey, we can do better! And because she believes in free markets, it must be that old technology (and indeed newer technology may have marginal benefit) is the culprit, not human greed or laziness or other deadly sin. So she goes, touts, implements and there is some success. However, then the giants will wake up to the threat. They will magically find the way to be more effective, as they always could have been, and they may even grudgingly implement some parts of new technology. And so the margin for the disruptor quickly disappears, and things will return back to the normal state of affairs, where companies can lazily collect fat paychecks for doing the necessary minimum. It's actually win-win for everybody, customers get a small technology/process upgrade, and she is now in the club!

The only minor problem is that this economic model is far from being optimal, but no one really worries about that except academic economists, since no one really knows how to attain the optimal model in the human society anyway.

Re: Theranos Has Struggled with Blood Tests

#33
post #27

> Mr. Balwani replied the next day, copying in Ms. Holmes. “I am extremely irritated and frustrated by folks with no legal background taking legal positions and interpretations on these matters,” he wrote. “This must stop.” Wow. What a terrible response to get from company leadership. It should be completely appropriate for an employee to bring a concern to the attention of leadership based on a plain-English reading…

Without seeing the full emails, I'm hesitant to judge. The excerpt sounds reasonable, but for all we know, the subject line could've read, "WHAT WE ARE DOING IS WRONG!"...I thought company lawyers generally frown upon speculation of legal matters via email. Not necessarily to stamp out internal and genuine complaints, but because they end up being a rich source of material to be taken out of context should litigation come up...that said, Mr. Balwani probably should've kept that in mind before writing something that appears quite dickish when excerpted in an investigative news report.

The other parts of Theranos's media strategy, according to the WSJ, doesn't seem particularly friendly:

- Threatening to sue a widow whose Theranos-employed husband expressed doubts to her before killing himself.

- Going around to people who had been interviewed by the WSJ and asking them to sign statements (before the story was even published) that the WSJ had misquoted them.

- Holmes ignoring WSJ for _five months_. Then standing them up last week. The CEO is famous for being an inspirational, thoughtful speaker but can't even make time in _five months_ to give a bland statement of defense or explanation to the Wall Street Journal, on a story that strongly hints at violations of federal health regulations? It's one thing to refuse comment when a news organization ambushes you the night of the deadline -- it's inexcusable to hide for five months..._especially_ if the company isn't actually doing anything wrong.

Re: Theranos Has Struggled with Blood Tests

#34

In startup-world, this is known as "faking it until you make it." Well done Theranos, keep at it!

>Well done Theranos, keep at it!

Really? What if your family member died because of inaccuracy of Theranos' results? Would you still cheer for them?

This whole article is extremely damning. Some stuff just makes your head spin:

>Carmen Washington, a nurse who worked at a clinic owned by Walgreens in Phoenix, says she began to question Theranos’s accuracy after seeing abnormal results in potassium and thyroid tests.

>She says she raised her concerns with the drugstore operator and Theranos’s lab director, asking for data to show that the company’s finger-prick testing procedures produced results as accurate as blood drawn from a vein.

>“They were never able to produce them,” she says. Ms. King says the company did show detailed testing-accuracy data to the nurse.

Anyway, if you ever need any tests done, stay away from Theranos.

Re: Theranos Has Struggled with Blood Tests

#35
post #33
post #27

> Mr. Balwani replied the next day, copying in Ms. Holmes. “I am extremely irritated and frustrated by folks with no legal background taking legal positions and interpretations on these matters,” he wrote. “This must stop.” Wow. What a terrible response to get from company leadership. It should be completely appropriate for an employee to bring a concern to the attention of leadership based on a plain-English reading…

Without seeing the full emails, I'm hesitant to judge. The excerpt sounds reasonable, but for all we know, the subject line could've read, "WHAT WE ARE DOING IS WRONG!"...I thought company lawyers generally frown upon speculation of legal matters via email. Not necessarily to stamp out internal and genuine complaints, but because they end up being a rich source of material to be taken out of context should litigation…

True. Concern about legal issues is what leads one to consult counsel in the first place typically though. Counsel discourages speculation by people who aren't involved and aren't the right people to be discussing it - like they've read a news article. I haven't heard anyone discourage genuine inquiry into a specific issue they're concerned about, and that it's appropriate for them to raise. It sounds like the employee had specific knowledge about an aspect of the company's operations. The word speculation is used a lot in that context, but every piece of legal advice I've ever received (outside of impersonal training) started with me thinking: it seems like this might be a problem ... I wonder if it's really a problem or not ...

Counsel also gives training about when to ask for legal advice and how to handle privilege and confidential communication, which doesn't sound like were followed here (or maybe never provided). As you say, it could be a liability during litigation. However, the response to that could have been "I've added our legal team for input on the issue you've raised. Please don't discuss legal issues except in privileged communication with our legal team." I guess that's easier to say and do when you have inhouse counsel. -g-

I would also hope that a thread like that would be deemed to be protected by privilege if counsel were immediately added like that as part of a request for legal advice. Perhaps someone more familiar with the boundaries of privilege could comment. From what I understand though, opposing counsel are usually pretty hesitant to attempt to pierce privilege, especially if there's a tinge of legitimacy on it. E.g., random guy raises legal concern to superior, who immediately involves counsel. Opposing counsel has to actually attempt to make the case that it's not privileged communication, which they are reluctant to do in such cases (but doesn't mean it can't happen).

Re: Theranos Has Struggled with Blood Tests

#37

Side note: Did anyone else find the writing for this article absolutely horrendous? “They were never able to produce them,” she says. Ms. King says the company did show detailed testing-accuracy data to the nurse. I would have flunked freshman-english if I wrote papers like this. There was zero effort to link thoughts together all-throughout the piece. I thought the point of a pay-wall was to promote and support good…

I found it to be consistent with most similar pieces. Also, the author has won a Pulitzer for investigative journalism.

Re: Theranos Has Struggled with Blood Tests

#38
No fan of this bizarre Illuminati-backed startup, but this article reads like a well funded hedge fund hit piece. Maybe some players shorting OTC contracts on their stock? The biotech industry is heavily manipulated so if they're facing this kind of opposition, maybe it really does make sense to have guys like Henry Kissinger on the board ...

Re: Theranos Has Struggled with Blood Tests

#39

>>Theranos claims that the usual delay of testing in centralized laboratories is approximately 3 days and that they will generate and deliver their data much faster (e.g., within 4 h). The 3-day delay claim is not accurate. The bulk of laboratory testing in centralized laboratories is completed within an hour or two (calculated from time of sample collection to time of results posting for physician review). For examp…

I would agree from an end user POV (I have to do a set of bloods every 6-8 weeks) the delay is getting test results from lab to specialist.

Though in the UK the fractured nature of the NHS means I can't get my tests done at a hospital near work - I have to take a days leave.

I wonder if There a market for mobile blood testers who come to your work place to take the sample.

Re: Theranos Has Struggled with Blood Tests

#40

>>Theranos claims that the usual delay of testing in centralized laboratories is approximately 3 days and that they will generate and deliver their data much faster (e.g., within 4 h). The 3-day delay claim is not accurate. The bulk of laboratory testing in centralized laboratories is completed within an hour or two (calculated from time of sample collection to time of results posting for physician review). For examp…

> This is the same kind of bullshit I see in academia, where a new technology is promised to replace an old technology that works fine, but now they have a 9 billion dollar valuation! I am not sure it is bullshit, maybe it's just competition? Over time, companies within an industry become complacent, cut costs, and decrease quality of service. Somebody (a young idealist perhaps?) comes along and says, hey, we can do…

>>win-win for everybody

Worst case is that their technology has a few percentage points better outcome, perhaps by selectively sampling candidates during clinical trials or combining it with an existing method, and everybody gets charged a ton more money.

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