I'm surprised this isn't mentioned here more clearly: Some high end cases like the be quiet silent base I'm using have the option to mount the graphics card vertically, basically parallel to the mainboard, in a separate anchor slot. It needs an additional connector cable (~$20), but other than that is easy to setup, looks better with a look-in case (the illuminated fans face the glass side) and the weight pulls on a…
Example: Silver Stone Fortress case https://bjorn3d.com/2010/05/silverstone-fortress-series-ft02...