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Testosterone is the drug of the future

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281–290 of 308 posts

Re: Testosterone is the drug of the future

#282
post #270

Earlier quoted context omitted.

I would think the ratio would have been MORE skewed in the past because war and violence were much more prevalent.

No where near. WW1 (which was by far the most deadly war prior to WW2) killed around 10 million military personal[1]. Assume they were all male. World population in 1918 was about 1.8B. Breaking those 10 million deaths over the 4 years of WW1 gives around 1.4 deaths per 1000 people on earth. Maternal mortality in England and Wales was around 40 deaths per 1000 births in the same period (England and Wales probably had…

I'm not sure how to convert from deaths per birth to deaths per people. Women generally had multiple children.

I think multiplying deaths per birth by births per capita should do it.

Re: Testosterone is the drug of the future

#283
post #55

MD here. Just remember that women live longer than men. Although it'll never be proven that hormones are part of that provess, I think it's a good assumption. Many males as they get older become more lovable and more pleasent to be around because of natural hormone declines. There are a ton of health issues such as balding, coronary artery disease, prostate cancer, obstructive sleep apnea that are related to testoste…

> Many males as they get older become more lovable and more pleasent to be around because of natural hormone declines.

Misandry much?

Re: Testosterone is the drug of the future

#284

Earlier quoted context omitted.

>>Many males as they get older become more lovable and more pleasent to be around because of natural hormone declines. I resent that. I don't have low testosterone but I'd still say I was a loving father and husband and a generally good person. Being "manly" doesn't mean being a dick, quite the opposite.

I resent that. Perhaps at a certain testosterone level, this sort of statement wouldn't bother you so much?

Let me just stick my nads in a vice and re-read it.

Re: Testosterone is the drug of the future

#285

Can anyone link to a gwern-style review of it? Unfortunately a google search for the same just yields a bunch of T-Nation style spam aimed at wannabe bodybuilders.

Gwern wrote a section about Testosterone in Nootropics article: http://www.gwern.net/Nootropics#testosterone

I like the experiment it proposes, although I wish someone else tried it first.

Re: Testosterone is the drug of the future

#286
post #268

Earlier quoted context omitted.

10 000 IU a day? Was that a typo? How did you got that target? Just asking because I was considering 10 000 IU a week following my MDs advice (which is already higher than what it the normal off the shelf dose: 1000 IU a day).

I'm also taking 10,000 UI daily. Anything below 20,000 UI daily is fine and non-toxic. References - pubmed.

Although safe, according to current search, there's no benefits from supplementing 10,000 UI daily (2,000-5,000 being recommended dose) — http://examine.com/supplements/Vitamin+D/

This doesn't prove that 10,000 is unnecessary, but there's no proof that it's necessary either :) (or is there?)

On the other hand, just recently a Polish study showed 6,000 IU improving rowers metabolism and performance — http://suppversity.blogspot.com/2015/02/6000iuday-of-vitamin...

However, it's unclear if lower dose would lead to similar results or if this is due to any other factors.

Re: Testosterone is the drug of the future

#287

Transwoman here, and I have some personal experience in this regard. I've been on T blockers for about 2 years, and I have seen significant mood, hair, and skin improvements, not to mention a lower resting heart rate. My chances of getting prostate cancer have been reduced to basically nil, which is pretty great. A significant portion of the benefits are from the estrogen, but just reducing bioavailable T does make a…

I'm sure whoever is prescribing you estrogen has told you that synthetic estrogen is incredibly hard on the liver. The reduced risk of you getting prostate cancer is as far as I understand it FAR outweighed by the likelihood that at some point you will have liver issues to deal with. Also, I am on TRT and this is somewhat anecdotal (although many 'bodybuilder' types that use testosterone support this) I have noticed the effects on skin mood and hair are stongly related to estrogen, prolactin, and progesterone levels (meaning they should be in the normal range for male or female depending on what your goal is wrt testosterone). I also agree with the commenter somewhere on here that mentioned he feels the 'roid-rage' when he is low. Also anecdotal but generally agreed upon by the community is that the mood swings come from actual 'swings' of testosterone (and bad moods are when you are low, they should call it roid-affection instead). FDA approved esthers in the US (for injection) do not allow precise daily control to mimic the natural cycle, so there can be some very minor mood changes throughout the week (my dr is open minded and lets me pin the cypionate twice weekly) but I would honestly suggest that your friend had some placebo effect goin on there. As for his 'back-ne', I would check my prolactin levels if I had bad acne on my back (sometimes I do get it, and the levels are always slightly elevated... what to do about it is another story).

Anyway, all due respect of course and I have much admiration of anyone who goes through such great lengths to 'be themselves' but please do make sure you are educated on the risks and minimizing them (I remember hearing it mentioned that the patches of estrogen are much easier on the liver than injections but that was from a tv show I think so take it with a grain of salt) I do believe that you are correct in saying >A significant portion of the benefits are from the estrogen, I just don't think you realize how much. As someone who lost a fair portion of my natural production almost instantly I can say with confidence that even if one were considering to transition to the fairer sex, losing your test without boosting the estrogen has pretty much NO positives except perhaps the reduced prostate cancer risk.

Re: Testosterone is the drug of the future

#288
post #2

Read about it 15 years ago in a Belgian magazine. A Belgian doctor was claiming the same. To be quite honest I use it already for 15 years and indeed it changes you. It helps me to be in "sana in corpore sano". Let's hope the negative health impacts on long term are not to bet so my body stays sano :)

Would you be kind enough to share your experience? I ask you this as a 29 yrs old who's mortified of aging and feels guilty as hell for having a "all-day-sitting" job.

I don't think more testosterone will help if you are sitting all day. You'd have to make up for all that sitting time with gym time otherwise even low dose testosterone will do nothing but help you gain hair and fat (well and some muscle even if you are sitting but it will probably be negligible). When I first got on testosterone I realized why most males always envied my ability to eat whatever I want without putting on body fat. That changed immediately, within a week I had to watch what I ate bc I noticed some fat building on my lower abdomen.

Re: Testosterone is the drug of the future

#289
post #55

MD here. Just remember that women live longer than men. Although it'll never be proven that hormones are part of that provess, I think it's a good assumption. Many males as they get older become more lovable and more pleasent to be around because of natural hormone declines. There are a ton of health issues such as balding, coronary artery disease, prostate cancer, obstructive sleep apnea that are related to testoste…

Just remember that women live longer than men. I find it remarkable that people state and accept this in such matter-of-fact fashion, rather than seeing it as an issue. Pretty much all statistics that go the other way around are seen as a problem that needs fixing. (If you disagree, please provide a counter-example. I.e. something that shows higher disease or death rates among women that is discussed as a matter-of-f…

I completely agree. We should drive more women into suicide.

Re: Testosterone is the drug of the future

#290
post #166

Assuming there are a significant number of men on here who hope to some day have a family, it's inportant to note that a significant side effect of exogenous testosterone administration is male infertility. Simplified, the excess testosterone in the blood stream sends signals that shut down the hormones essential for sperm production. This may not matter if you are mid life or older and already have children, or if y…

HCG, Clomid can be taken to counter that.

And anastrazole. However you would have to stop taking exogenous testosterone and take these meds and it still potentially may not work and you could require surgery for extraction. They would raise testosterone levels, but you would not see the same "physical benefits" as a testosterone gel would provide.
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