Probably not hugely more significant, but there are differences. A workstation should be segmented and limited in the range of nodes it can communicate with, if you're running your network properly. A server will likely be in a segment that has much broader access to it, unless you're doing micro-segmentation, and doing it well. By construction, a server set up by a workgroup team outside your core IT server administration staff is unlikely to be properly segmented. And if you're doing traffic analysis to look for rogue behavior, it's harder to spot from something that profiles as a server, because, again, you expect a server to have lots of contacts within the network. Counterbalancing that, if it profiles as a server, you should be more suspicious of any outbound activity.