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Psilocybin desynchronizes the human brain

nature.com

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Re: Psilocybin desynchronizes the human brain

#271

Post by Litost »

zild3d wrote: post #182
RamblingCTO wrote: post #181

Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…

> We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. Worth noting the research is on psilocybin with supportive psychotherapy, not just take some mushrooms you got from a guy and have at it. https://www.hopkinsmedicine.org/news/newsroom/news-releases/...

There's a good documentary about the John Hopkins research on treating drug resistant depression with psilocybin which unfortunately isn't available any more via the BBC: https://www.bbc.co.uk/programmes/m000w7bq

From my limited personal experience and having attended various psychedelic talks and integration workshops etc., set, setting and (post) support are all really key to help turn what can be a potentially life changing/affirming/challenging event into a beneficial one.

Re: Psilocybin desynchronizes the human brain

#272

Post by 47282847 »

isatty wrote: post #168
kjkjadksj wrote: post #69

Earlier quoted context omitted.

Part of the lesson of this story is the danger of having a gun in the home at all. He could have been sober and depressed and did the same just as easily thanks to having access to a gun. There's a lot of statistical evidence for how dangerous situations like depression or domestic violence can become once a gun is nearby.

On the other hand, he could’ve very easily found another way without the gun.

Anecdotal evidence: I was close to suicide a couple of times in my life, and believe I would have done it if I had had a weapon just lying around or within easy access. Thankfully I did not. (Non-US, access to guns highly restricted.)

Re: Psilocybin desynchronizes the human brain

#273

Post by tambourine_man »

bitcoin_anon wrote: post #235
tambourine_man wrote: post #208

Earlier quoted context omitted.

The amount of antivax shit that floats around in a supposedly well informed community such as this is nauseating. Makes me lose my faith in humanity a bit every time I read it.

Remember when the authorities pulled the JnJ vaccine due to adverse events after it was administered to millions of people? It seems some caution was warranted, no?

If you mean in the US, a huge amount of caution was taken, as it's always the case. Vaccine approval are among the most rigorous processes we have.

J&J and AstraZeneca were vastly safer than catching COVID. The FDA later switched to mRNA-based ones, which are also extremely safe.

Re: Psilocybin desynchronizes the human brain

#274

Post by Xen9 »

RamblingCTO wrote: post #181

Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…

No matter how good one's ground is, lots of LSD in a city apartment will likely drive you crazy.

I never have had a bad trip, except for that time I took 800 mu-g GG in my tiny apartment. I became insanely restless, waking up 12 hours later trying to open the window to get to more natural environment. My lights were dropped on the floor, as well as plenty of water, broken electronics and ruined papers.

Since then I've learned to use music and earplugs; keep the windows open; have high CRI bulbs; keep lots of plants; and to never hesistate going to an ice shower when feeling like a confused and mentally stressed ape.

The level of control one wants, I believe, is roughly the same as beating a nightmare disorder with lucid dreaming. One ALSO must have familiarity with "foundations" of the world, or else they will end up doing dumb stuff with dumb beliefs. By foundations I mean sort of at least grasping that it's all arbitary and then building what you want on That.

Re: Psilocybin desynchronizes the human brain

#275

Post by hcks »

RamblingCTO wrote: post #181

Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…

What if psychedelics are actually not gates to an enhanced consciousness for the happy few?

What if actually your teacher was right, and they’re just dumb intoxicants that have no upside and a small chance of ruining your life?

Re: Psilocybin desynchronizes the human brain

#276

Post by Unbefleckt »

loa_in_ wrote: post #84
Unbefleckt wrote: post #52

While it's amusing in the short term, the long term side effects for me were awful. I felt like my brain was slow and unfocused, I was no longer quick in conversation or able to concentrate as well as usual, I felt disconnected from myself, sort of like when you recall a memory so old that it seems like it belongs to someone else, I had a headache for almost 3 weeks. Throwing this in here as there are a fair few "dud…

Mushrooms are very contradictory in their nature to the modern "cog in the machine" lifestyle. It's a bit like being subjected to a software fuzzer. I imagine if learning from one's inputs, one will be afterwards less sure of concepts one was very sure about, but also less sure about concepts thought previously to be impossible. That will surely increase cognitive load, especially when one's life is pretty straightfo…

This is the best insult I've ever received.
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