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Insulin is way too expensive. California has a solution: Make its own

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271–273 of 273 posts

Re: Insulin is way too expensive. California has a solution: Make its own

#271

Earlier quoted context omitted.

Its easy to point at what doesn't work well, there's tons and tons of things that work great that nobody talks about. Municipal broadband: the best broadband in the entire United States is provided by the municipality of Chattanooga. [1] Post: The USPS is the most trusted brand in the United States, above FedEx and UPS. [2] Transit: The New York City Subway is the 3rd largest metro rail system on earth after London a…

> Transit: The New York City Subway is the 3rd largest metro rail system on earth after London and Guangzhou It’s also the worst large metro system, by timeliness and reliability, in the world, despite being very well funded. People in the rest of the country aren’t exactly unaware of New York. But its transit, housing, and public school systems are a poster child for how government-run services are terrible, even wh…

> But we don’t have Swedes running our government services, we have Americans. It is what it is.

Gotta love the fatalism that ensures it stays that way. This is really how America lost it's way - acceptance.

Re: Insulin is way too expensive. California has a solution: Make its own

#272

Earlier quoted context omitted.

This "article" has one paragraph dedicated to actually explaining why drugs are expensive, and it says it's because of patents. It also tries to blur between patents and exclusivity. Exclusivity is usually 3 years (5 for new antibiotics and new chemical entities). Patents are 20. Exclusivity is a very small portion of intellectual property protection. I would call that dishonest. The FDA does not control drug patents…

> Abolishing the FDA […] would eliminate all the other things they do, like making sure drugs work and don't kill people. Like they did with Thalidomide? Abolish both the FDA, and IP.

Yes... Thalidomide was never approved in the US.

Re: Insulin is way too expensive. California has a solution: Make its own

#273

Earlier quoted context omitted.

In 1938, the FDA started reviewing and approving drugs. In 1960, Richardson-Merrell applied for approval for a drug called Thalidomide, a cancer treatment. They had clinical trials that included pregnant women. They were rejected six times . In the UK, The Distillers Company (Biochemicals) Ltd, a subsidiary of Distillers Co. Ltd marketed thalidomide as Distaval, a remedy for morning sickness. Their advertisement clai…

I remember reading an archived copy of the FDA press release after they finally approved beta-blockers, a medicine that had been approved and widely distributed in Europe for some ten years. In the press release, the FDA was proud to announce that as a result of their approval, beta blockers would save the lives of an estimated 10,000 Americans every year. That is to say, the inefficiency of the FDA was, in the words…

> A journalist asked if this would negatively impact the safety or efficacy of the vaccine to which the FDA head confidently replied that it would have zero material impact. It makes you wonder, if they are capable of quickly making approval decisions without sacrificing safety or efficacy standards, why is that not standard operating procedure?

That's easy. The normal process has multiple trials:

Phase 1: 50 people Phase 1: 200 people Phase 3: 100,000 people

Normally, you pass each phase before exposing a larger number of people to risk. More people means you can find rarer and smaller effects, but if you haven't tested on The expedited process tests it on 100,250 people at once. THOSE people are exposed to more risk, but the safety of the vaccine is the same. And because the vaccine was proven safe, those people were not negatively impacted any more than if they had followed the normal process.

> There are no answers that don't lead one to conclude that the FDA is a bloated, bureaucratic, wasteful mess.

No, you're just not actually looking.

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