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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

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Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#271

Post by lbeltrame »

jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

The latest data (preprint, not peer reviewed etc etc) mention memory B and T cells up to 8 months after recovery from the illness. This means that an immunity of one year is probably likely. This would be probably enough to quench the spread, but not to eradicate the virus.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#272

Post by frockington1 »

fuoqi wrote: post #171
andrepd wrote: post #167

Earlier quoted context omitted.

Trust. Russia and China lie through their teeth on everything and anything. It's irrelevant whether or not they are lying in this particular instance: they cannot be trusted.

As if "the West" and the US in particular don't lie left and right if it helps to promote their agenda. It's a simple matter of who aligns with whom.

Try opening a publishing paper in China that runs #NotMyPresident with a picture of Xi. You may find yourself being re-educated somewhere

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#273

Post by jashephe »

himlion wrote: post #26
zpeti wrote: post #17

Seems like a good time to buy shares in whoever manufactures industrial sized extra cold freezers.

So which company benefits the most here? From a cursory googling the following seem decent: - The Whirlpool Corporation - Electrolux AB - LG Electronics Inc. problem is these companies have a lot of exposure to other sectors as well of course.

Based on this NYT article [1], some logistics companies planning to store and transport the vaccine are using freezers from Stirling Ultracold. It may just be a curiosity, but their freezers (as the name would suggest) use bona fide Stirling engines rather than the typical two-stage compressors used in most ULT freezers.

As someone in life science research who uses plenty of -80 freezers, I've always been curious about Stirling Ultracold. Maybe they're on to something after all.

[1] https://www.nytimes.com/2020/09/18/business/coronavirus-covi...

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#274

Post by FiReaNG3L »

selectodude wrote: post #238
jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

The Ebola vaccine required -80 C storage as well and they got it into literal war zones. It’s a difficult problem, but a solved one.

Depends on the scale - we are talking mass vaccination of the whole planet here.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#275

Post by Zenbit_UX »

untog wrote: post #37
TomGullen wrote: post #2

Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!

The markets seem to wildly yo-yo with every piece of negative and positive news. Case in point: Zoom is currently down 10% but I’ll bet it will have rallied by the end of the day.

It's more than zoom, everything that's gone up from the pandemic is dropping: amzn, meli, jmia, se, shop, sq. The markets had them valued at a premium due to their monopolies in the pandemic but retail stocks are now trending up premarket: bbby, etc.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#276

Post by sambeau »

jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

+ ~90% of individuals achieve immunity

It could also refer to 90% reduced severity.

A 60% vaccine can reduce the severity of the illness by 40% so only 40% of the expected number end up in hospital.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#277

Post by rocha »

mwexler wrote: post #220

Besides the 90% protection, does the research or testing imply a reduced severity should one actually catch the disease by rolling a 92 on the dice? I'm presuming the white blood cells and t-cells can act as de-escalators but I don't really know.

This is a nice thread on the subject: https://twitter.com/nataliexdean/status/1310613702476017666?...

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#279

Post by bluGill »

romanovcode wrote: post #164
tuna-piano wrote: post #153

For those wondering how their vaccines will be distributed among countries during the next year when supply is constrained... it seems complicated. Pfizer is a US company, but has at least one key ingredient from Austria, is made with technology from Germany, has manufacturing in US+Europe, etc. Pfizer's CEO answered this question this morning on CNBC. Pfizer has two separate manufacturing divisions- one in the US (M…

Why not share the knowledge make the vaccine in all three countries? AFAIK for the last 2-3 days EU and US are partners again, not enemies.

I would assume that the countries are the only ones with a factory that is capable of making this. Give me a few billion dollars and a year and I can set up another factory, but it would have been too risky an investment 1 year ago (before COVID), or even 3 months ago . Even now it is too risky an investment as the current factories can produce a lot of vaccine, and there are other candidates that also have factories, so odds are the world will be vaccinated before my 1 year factory comes online.

A 1 year factory build is extremely fast - freely trading money for time. A more reasonable schedule would be several years (a lot cheaper)

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#280

Post by danesparza »

selectodude wrote: post #238
jakozaur wrote: post #214

Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?

The Ebola vaccine required -80 C storage as well and they got it into literal war zones. It’s a difficult problem, but a solved one.

My understanding is that -80c cold storage isn't widely available. The Ebola outbreak might have shown how to get small numbers of doses into a warzone, but scaling this up might prove to be a logistical difficulty.

"Once a provider receives that vaccine, it really starts the clock that the vaccine needs to be administered within five days of when it's put in the refrigerator"

Source: https://www.cbsnews.com/news/coronavirus-vaccine-distributio...

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