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Creatine raises brain energy levels and slows cognitive decline: study

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Re: Creatine raises brain energy levels and slows cognitive decline: study

#261

Post by fer »

pitched wrote: post #180
fer wrote: post #138

Earlier quoted context omitted.

.001 for creatine levels isn't surprising; that's a lot of creatine. I'd explain the cognitive tests with the practice effect, because it is unlikely that creatine had such a massive effect and we only discover it now.

I hear about tech bros taking creatine these days with the tone of voice that they use to talk about microdosing. So I can’t imagine it having zero effect. What I worry about more is that it has more to do with fixing a deficiency. That being deficient in creatine causes a cognitive loss more than supplementing causes a boost.

As someone who's microdosed (though mostly normal-dosed and occasionally megadosed) in the distant past, the whole microdosing fad was equal parts entertaining and baffling. Anecdotal, but from all people I know that has taken psychedelics, only one doesn't find it to be a waste.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#262

Post by [deleted] »

OutOfHere wrote: post #20
aatd86 wrote: post #15

I feel like crap when taking creatine... Actually most of these purported supplements are a no go. Preworkouts would work first session then make me ultra tired, caffeine is fine as long as I 'cycle' it... Wondering strongly if those studies are not just to sell more cheap supplements... As long as for some reason we find that it has some level of effect on most people. It has some effect for sure but not sure it is…

What precisely does it mean to "feel crap"? Is that how you would describe it to a doctor? You seem to also be making broad generalizations. Overall your comment is providing zero insight whatsoever wrt creatine. In my experience, those with creatine intolerance, especially if assuming it's not taken late in the day, have unresolved excitotoxicty/inflammation/pressure/headache/migraine issues in their brain. Also, be…

[deleted]

Re: Creatine raises brain energy levels and slows cognitive decline: study

#263

Post by gwern »

tom_ wrote: post #115
narmiouh wrote: post #22

Earlier quoted context omitted.

What did you use to determine this? Ask because many of the online tools I've tried, they will sometimes tag what I've written at 30-40% AI written and sometimes purely AI written stuff is flagged as 60-70% AI

"Quietly". Also, the first paragraph. If this wasn't actually 100% LLM generated, one has almost certainly been used to imbue it with the flavour.

(That LLM rhetorical tic is especially funny because it's so obviously nonsensical in almost all contexts like OP - what would it mean for creatine supplementation's effects to not be 'quiet' and to be loud? The pills come with little Bluetooth speakers? You are trapped on the toilet for several hours a day with GI issues? The world suddenly takes on psychedelic colors and imagery all day long?)

Re: Creatine raises brain energy levels and slows cognitive decline: study

#265

Post by keane »

jshaqaw wrote: post #136

I usually throw my 5g scoop on my morning coffee where I don’t notice it exists. Any reason not to take it with coffee or am I doing it right?

“potentially deleterious interaction between caffeine and creatine” in https://doi.org/10.1097/WNF.0000000000000102 mentioned later/elsewhere in today’s thread: https://news.ycombinator.com/item?id=48348670

Re: Creatine raises brain energy levels and slows cognitive decline: study

#267

Post by j45 »

the_sleaze_ wrote: post #152
cryptoegorophy wrote: post #90

Earlier quoted context omitted.

What exactly does it do? What is brain energy?

A good question, but we don't know what anti-depressants do or how they do it, same with anti-psychotics, mood stabilizers, psychedelics, etc. I think we can say we have good theories for creatine. We do know that it does do something at certain doses.

There are lots of studies. It's possible to find satisfactory information. Creatine has been studied for a very long time.

First hand experience for many is a noticeable improvement, especially during busy/sleep minimizing times, to the point where it can sometimes be a substitute for caffiene without the crash.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#268

Post by mmanfrin »

syspec wrote: post #266

For someone who's always been interested in creatine, but never tried it due to being overwhelmed by choice... what's a standard go to product?

Powder, from any company that you find reputable. I like the micronized form. I would avoid any of the gummies, as a huge percentage of them have nowhere near the amount of creatine they claim (I believe the cooking process denatures it or something but this is just conjecture).

Re: Creatine raises brain energy levels and slows cognitive decline: study

#269

Post by [deleted] »

pitched wrote: post #180
fer wrote: post #138

Earlier quoted context omitted.

.001 for creatine levels isn't surprising; that's a lot of creatine. I'd explain the cognitive tests with the practice effect, because it is unlikely that creatine had such a massive effect and we only discover it now.

I hear about tech bros taking creatine these days with the tone of voice that they use to talk about microdosing. So I can’t imagine it having zero effect. What I worry about more is that it has more to do with fixing a deficiency. That being deficient in creatine causes a cognitive loss more than supplementing causes a boost.

[deleted]

Re: Creatine raises brain energy levels and slows cognitive decline: study

#270

Post by mmanfrin »

coreyburnsdev wrote: post #231
firefax wrote: post #220

Earlier quoted context omitted.

Normally I wouldn't ask this, but having seen the effects of Alzheimer's I must ask: is there any evidence that taking creatine will harm my brain? Let's be real: I take a lot of edibles. I smoke sometimes on a hike. Every once in a while I get a Guiness and a gyro. My health is by no means perfect, and if I'm willing to take in literal poison (yes, alchohol is that dangerous that I say such things even about my prec…

if you're worried about Alzheimers why do you take Marijuana? that would be the first thing to do in prevention

Why would it be? There's no known link at all.
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