It's night and day. I'm a PhD student currently writing my thesis in Typst. On paper this is an absurdly risky decision: it's a new technology without a huge user-base, it's not totally stable yet, etc. But I tried Typst and I had no choice. It was obviously the right thing to do, even though I'm going to have to make a pixel-perfect clone of my university's LaTeX template. I've been using LaTeX for over ten years an…
Maybe the best compromise here is a markdown interpreter that converts to latex so you can use existing libraries and templates but not have to worry as much about syntax.
I've tried writing Org and compiling it to LaTeX, but gave up this idea because ultimately I had to figure out idiosyncrasies of both LaTeX and Org-mode engines.