Live data from Hacker News

Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

gavi.org

261–270 of 393 posts

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#262

Earlier quoted context omitted.

Conspiracy theory: they want old people to die.

Finally, affordable housing!

Yeah, screw those old people with their houses! We should deliberately kill them off so that we can have cheaper houses! But please, don't let the next generation do that to us when housing turns out to be expensive for them too!

Brilliant.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#263
post #238

Earlier quoted context omitted.

This isn't a conspiracy theory - I worked on projects around that during graduate school, and talked to my colleagues who worked on them. Cost-effectiveness thresholds are a consideration that goes into how widely a vaccine will be rolled out, etc. That was, for example, why boys were originally not part of the recommendation for the HPV vaccine. It would double to cost, while doing very little to prevent cervical ca…

Cost considerations would be more from the CDC's Advisory Committee on Immunization Practices, not the mentioned above United States Preventive Services Task Force. (Oh, and I see that another comment parallel to mine up there now mentions ACIP too...) In any case, somebody thinking that evaluating safety and efficacy aside from cost considerations means that there's collusion with pharmaceutical companies would be a…

have you ever wondered if it's a great idea to have former generals populate the defense department, procurement, and revolving door employment with defense contractors? what could go wrong? what could go expensive?

you are one of the generals in this scenario, thinking that evaluating safety and efficacy aside from cost considerations couldn't possibly lead to higher costs because you yourself and everybody in your industry are so darn smart, clever and by god ethical.

what did you do before this? work on creating the covid 19 virus, or just calling people who questioned it "conspiracy theorists"? what's that, you were in caves tracking down the zoonotic transfer, which you'll find any day now, scientific consensus and all, peter daszak assured you you'll find it and he's beyond reproach!

and I resent you saying that I'm a conspiracy theorist because I have not said any of this is happening, I am pointing out the vector where it could happen (go back, look, where did I say any of this was happening?)

it's simply, methinks the lady doth protest too much

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#264
post #48
post #40

Earlier quoted context omitted.

In Denmark you can. I was in my mid thirties when I went to my doctor to ask them to prescribe it. Before each shot I would go to the pharmacy and buy one dose and go to the doctor to have them administer it for me (if I wanted to). At that time I think it was free for teenage girls, now it's free for teenage boys as well.

The evolution of who gets HPV vaccines is really interesting. At first it was young women, as vaccinating young men had a very marginal decrease in cervical cancer rates via indirect protection (which itself is a function of how many young women are vaccinated). Then as HPV infection was linked to more cancers, vaccinating young men crossed the cost-effectiveness thresholds many governments use. Vaccinating older pop…

Seriously. My memories of this vaccine are so foggy because I distinctly remember being told "its not effective for men" and that it would be an expensive out of pocket cost. Yet, the whole point would always have been to prevent the spread.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#265
post #66
post #18

If you're living in the US: please consider getting the vaccine, ragardless of your age. It was covered by my (rather shitty) health insurance. It consists of just 2 (EDIT: 3 for adults!) doses. It is recommended for both Males and Females.

I went to my local megacorp pharmacy out here in California, and asked about the COVID vaccine that’s no longer recommended by our anti-vaxxer overlords. Apparently, it’s about as easy to get as an old-school medical marijuana card. Results vary by state though. No need to travel to Canada or Mexico (yet).

You might not have the same experience in OK or FL

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#266

It’s insane to think that someday humanity will finally find a cure for cancer, and then after all this money and research and struggle people will just… choose not to use it.

There will never be a single cure to all cancers. Different cancers have different underlying mechanisms and affect different tissues.

Maybe. The fact that some animals are especially immune to cancers suggest there are ways to prevent the outcome (cell replication/mutation).

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#267
post #231

Good stuff. Australia has a target for eliminating cervical cancer by 2035 and ofcourse HPV is responsible for a large proportion of penile, mouth, throat and anal cancers as well. All my kids got free vaccinations at school. It is shocking that there are still places in the world where this is controversial. You can tell a lot about the qualities of a society by the way they care for their own.

You should think about how you would react to “you can tell a lot about the qualities of a society by the way they [detain people on Nauru | reject asyl seekers | don’t care for indigenous populations]”. I feel your comment is a generalisation and could be construed as provocation/trolling. Probably not your intention, but just so you are aware how this is coming over. Better maybe: “societies that have good health c…

Australian indigenous women do in fact have a higher risk of HPV and cervical cancer than the general population. We do need to do better but we also face some challenges in delivering quality services to rural and remote communities. Achieving a consensus amongst millions of people on how to run a country isn't simple and stupid shit often happens.

Anyway, well done Denmark. We are trying to do the same thing here in Australia with some success. Not sure how it became about the US but good luck to you all as well.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#268

Earlier quoted context omitted.

Hence the "H"

Although you are (as I understand) right, the question itself is valid, lots of diseases spread to species other than the one that is in the name… Chickenpox, monkeypox, swine flu, or even the Spanish flu.

Lots of diseases are potentially zoonotic. When diseases have animals in the name, it often just refers to zoonosis itself (except of course chickenpox). But when diseases or parasites have human in there name, it's almost always because it's a disease that only effects humans.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#269
post #185

Good to hear what's happening in the more advanced countries.

RFK Jr may be a bit biased, his opposition has been profitable > Kennedy for years has earned referral fees from Wisner Baum, a Los Angeles personal injury law firm that is currently suing Merck, alleging the pharmaceutical giant failed to properly warn the public about risks from its vaccine against human papillomavirus (HPV), Gardasil, according to financial disclosure documents filed by Kennedy with the Office of…

Remember to look for critical takes. I encourage you to look at stuff like this with an open mind, and if you disagree with anything, look into the details:

https://www.youtube.com/watch?v=HqI_z1OcenQ

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#270
post #127

Earlier quoted context omitted.

The other strains were not covered because they were not common. Now they are. Which means some new strain will become common. Is there any data on how quickly/easily new strains show up? I assume it's not as fast as cold/flu, but if it is people will need a vaccine yearly, and that's not realistic.

Also after some research about rate of change: It's extremely slow. HPV is a double-stranded DNA virus with very high replication fidelity. The emergence of types like 16 and 18 happened hundreds of thousands of years ago. I did know it was quite slow but not just how slow. Very long term vaccine efficacy is expected.

Not anti-vax by any means, but it's not too conclusive to use past mutation rate here because the presence of a vaccine targeting successful strains introduces a strong evolutionary pressure for the more rapid emergence of novel strains in the future.
Post reply on HN