Earlier quoted context omitted.
Both the DC and SF metro areas have Chili's, Target, and Outback. Can you articulate what made DC and SF "really amazing and different experiences" from one another, beyond vibes? Asking as an American who's pretty sure it's all the same here (and has traveled internationally to places where it's not).
I'll try. YMMV, but: DC: You can get just about any kind of food - because just about every culture in the world is represented. You can find some of the more home-y type menu options too for the same reason. For example, Greek restaurants where I am at don't generally have Taramosalata (carp roe dip). Due to the shorter flights to Africa, the is a much larger African population in the DC area. One trip, I bought som…
I know I can get Greek and Asian food in both St. Louis and Denver. I just confirmed that both cities have Greek places with Taramosalata; I know from dating a Chinese girl for a year that both of those cities have extremely authentic Asian places. I've seen gay men walking around in at least Denver and Calgary (not even US).
Now, being able to browse and buy a Nigerian movie at a gas station instead of needing to get it online is something that might qualify if it's truly exclusive to DC. The techie "tent city" in California is probably unique to California, you've got me on that one.
Having visited plenty of U.S. history/military/science/etc museums across several midwestern/western states, those could probably be argued either way. On one hand, of course every museum will have different artifacts/exhibits/etc that mean it's not quite the same at every one, and there are individual facts that you could learn at one but not another. On the other hand, I think the likelihood of coming across something in a US museum that noticeably expands my human experience is lower than the likelihood of that happening in another continent's museums.