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Fentanyl vaccine tested in rats

uh.edu

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Re: Fentanyl vaccine tested in rats

#261

Post by PragmaticPulp »

_yb2s wrote: post #176
PragmaticPulp wrote: post #160

Earlier quoted context omitted.

> The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine People start using drugs for different reasons. It's not correct to say that everyone starts abusing drugs as a form of pure escapism. A lot of drug users start because they're simply seeking recreation and someone is nearby to make drugs available to them. It's as si…

> Variations of this concept are frequently used by drug addicts to justify continued behavior. "It's not my fault, it's society's fault!". Taking ownership of actions and consequences is one of the key pivot points in helping people get control. I don't think these are mutually exclusive. Society wide problems cause a huge fraction of the population to experience severe emotional trauma, and the process of addiction…

Attempts to replicate the Rat Park experiment have failed: https://en.wikipedia.org/wiki/Rat_Park#Criticisms

It gets cited in a lot of pop-science and podcasts, but it's not actually the groundbreaking, universally-accepted study that people think it is.

Likewise Gabor Mate is more of a podcast, pop-science guy, not a real researcher. Take his podcast and YouTube content with a grain of salt.

Re: Fentanyl vaccine tested in rats

#262

Post by hammock »

notch656c wrote: post #240
hammock wrote: post #177

Earlier quoted context omitted.

Test strips: https://dancesafe.org/ Or on amazon

Test strips are just as or almost as illegal as the drug themselves in many state. Except without the huge profit margins to incentivize dealers to carry them.

Why are they illegal?

Re: Fentanyl vaccine tested in rats

#263

Post by iskander »

dlkf wrote: post #256
shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

> Why do so many people want to check out of life completely by abusing medicine? This isn’t how it works. Few people, if any, want to “check out.” What happens is that people are exposed to opiods via one of two channels (they are prescribed painkillers, or they party with someone who has acquired them) and they quickly get hooked because these drugs are cripplingly addictive. So the only “why” questions we have to…

>Society is not broken and we don’t need weird conspiratorial explanations for any of this.

Life expectancy plummeting through deaths of despair, juxtaposed with widespread addiction (as much to drugs without physical dependence as opiates).

Re: Fentanyl vaccine tested in rats

#264

Post by hammock »

makestuff wrote: post #185
hammock wrote: post #177

Earlier quoted context omitted.

Test strips: https://dancesafe.org/ Or on amazon

They give these out in NYC, but make a point to say that the test strips won't catch everything. So still be really careful if you go this route.

Yea it’s like skiing in avalanche terrain. Forecast and observation don’t remove the risk

Re: Fentanyl vaccine tested in rats

#265

Post by nicoburns »

dlkf wrote: post #256
shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

> Why do so many people want to check out of life completely by abusing medicine? This isn’t how it works. Few people, if any, want to “check out.” What happens is that people are exposed to opiods via one of two channels (they are prescribed painkillers, or they party with someone who has acquired them) and they quickly get hooked because these drugs are cripplingly addictive. So the only “why” questions we have to…

I think it's

> 1) Why do people take opiods the first time

that the GP is getting at. While doctors over-prescribing opiates is definitely a thing (esp. in the US), I'm not convinced that many people get hooked on opiates due to partying. I think it's more commonly:

"Used as an escape from a life that is unmanagable for some reason"

That's not conspirational. There's good evidence to show that life circumstances have a big effect on both initially becoming addicted and success when attempting recovery. The answer to this might look like a better welfare state or similar.

Re: Fentanyl vaccine tested in rats

#266

Post by elil17 »

Perenti wrote: post #223
elil17 wrote: post #25

Earlier quoted context omitted.

The article actually discusses this: “The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.

What about twilight anesthesia? With my cardiac problem, I can't have general anesthetics, but I can have Fentanyl/Midazolam to sedate and numb up a bit. Saying "it's specific to fentanyl" doesn't help those for whom fentanyl is a life saving drug. The reply above that the real issue is WHY Americans like fentanyl so much is on the money in my opinion.

Well the idea is not for everyone to get OUD vaccines. They would be targeted to people with OUD. If you did have OUD, this treatment would unfortunately probably not work for you due to your cardiac problem. However, depending on the severity of OUD and how effective this vaccine turns out to be, it might be worth forgoing the possibility of surgery.

Re: Fentanyl vaccine tested in rats

#267

Post by jvickers »

PragmaticPulp wrote: post #160
shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

> The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine People start using drugs for different reasons. It's not correct to say that everyone starts abusing drugs as a form of pure escapism. A lot of drug users start because they're simply seeking recreation and someone is nearby to make drugs available to them. It's as si…

Society encouraging people to take ownership of their actions and consequences is also part of how that would take place.

Re: Fentanyl vaccine tested in rats

#268

Post by TYPE_FASTER »

shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

It's not that simple: https://www.wcvb.com/article/ex-cop-describes-descent-from-h...

Re: Fentanyl vaccine tested in rats

#269

Post by awill88 »

shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

Whoa, you’re so out of touch with reality. Yikes.

Re: Fentanyl vaccine tested in rats

#270

Post by nicoburns »

PragmaticPulp wrote: post #160
shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

> The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine People start using drugs for different reasons. It's not correct to say that everyone starts abusing drugs as a form of pure escapism. A lot of drug users start because they're simply seeking recreation and someone is nearby to make drugs available to them. It's as si…

> A lot of drug users start because they're simply seeking recreation and someone is nearby to make drugs available to them

This is true for drugs in general, but not many people are stupid enough to take opiods recreationally.

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