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Post-SSRI sexual dysfunction

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Re: Post-SSRI sexual dysfunction

#261

Post by FilMo »

blockmarker wrote: post #155
symlinkk wrote: post #43

Has anyone taken SSRIs and actually thought it was worth it? I have severe social anxiety and I’m trying to decide if I should try medication or not.

Yes, but it is not an aspirin. Before trying medication try therapy with a psychologist.

I also agree. First of all, consult a specialist. Additionally, I need to say I always pay attention to all side effects indicated. I really treat with caution every prescription I get. As for Sertraline, I noticed that the generic one I got from https://www.canadapharmacy.com/ has less sides than the branded one. Don't know why there is the difference, but it still calms me down a bit.

Re: Post-SSRI sexual dysfunction

#262

Post by R0b0t1 »

ironmagma wrote: post #191
R0b0t1 wrote: post #177

Earlier quoted context omitted.

Heroin, interestingly enough. IIRC they screened pain medicine recipients for depressive symptoms and in this way determined opiates relieve major depression more efficaciously than SSRIs.

Yes, and a close relative (oxycodone) is something I’ve had experience with and can confirm it’s quite good at curing the depression. The problem is the permanent brain damage and/or death it will cause when taken long-term. Link https://www.drugabuse.gov/publications/research-reports/hero... >

I don't see opiates as a tenable longterm solution but I mentioned heroin because it's only long term side effect as far as I know is constipation, which can be managed. Same with morphine.

My point in bringing this up is why accept SSRIs if they have more side effects and are less efficacious than heroin?

Re: Post-SSRI sexual dysfunction

#263

Post by ironmagma »

R0b0t1 wrote: post #262
ironmagma wrote: post #191

Earlier quoted context omitted.

Yes, and a close relative (oxycodone) is something I’ve had experience with and can confirm it’s quite good at curing the depression. The problem is the permanent brain damage and/or death it will cause when taken long-term. Link https://www.drugabuse.gov/publications/research-reports/hero... >

I don't see opiates as a tenable longterm solution but I mentioned heroin because it's only long term side effect as far as I know is constipation, which can be managed. Same with morphine. My point in bringing this up is why accept SSRIs if they have more side effects and are less efficacious than heroin?

Heroin is highly addictive and has a high risk of overdose. There are alternatives to SSRIs, such as SNRIs and tricyclics.

Re: Post-SSRI sexual dysfunction

#264

Post by R0b0t1 »

ironmagma wrote: post #263
R0b0t1 wrote: post #262

Earlier quoted context omitted.

I don't see opiates as a tenable longterm solution but I mentioned heroin because it's only long term side effect as far as I know is constipation, which can be managed. Same with morphine. My point in bringing this up is why accept SSRIs if they have more side effects and are less efficacious than heroin?

Heroin is highly addictive and has a high risk of overdose. There are alternatives to SSRIs, such as SNRIs and tricyclics.

Both irrelevant with medical supervision. SSRIs are highly addictive too; many people never stop taking them.

Re: Post-SSRI sexual dysfunction

#265

Post by ironmagma »

R0b0t1 wrote: post #264
ironmagma wrote: post #263

Earlier quoted context omitted.

Heroin is highly addictive and has a high risk of overdose. There are alternatives to SSRIs, such as SNRIs and tricyclics.

Both irrelevant with medical supervision. SSRIs are highly addictive too; many people never stop taking them.

Overdose is not impossible just because there's a guy in a white suit telling you what to do. People will still take more than they should.

> SSRIs aren't addictive [1]

There are also a large number of side effects and risks associated with heroin; it's not just constipation as you say. [2]

[1] https://www.mayoclinic.org/diseases-conditions/depression/in....

[2] https://www.drugabuse.gov/publications/drugfacts/heroin

Re: Post-SSRI sexual dysfunction

#266

Post by teaearlgraycold »

notmymainlogin wrote: post #236
n8cpdx wrote: post #113

As someone dating in their 20s, it is getting hard to find people who aren’t having SSRI-related dysfunction. Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” They really seem to be handing out these serious, almost-impossible-to-withdraw medications like candy on Halloween. They don’t…

I really appreciate your comment, and value honestly, but this: > Recently met an older (early 30s guy) and it was seriously cool having a sexual experience that didn’t end with “don’t bother I’m just not going to finish no matter how long we go.” Reading that was like reading that your worst nightmare is actually true. nervous laugh As a guy in their 30s, on multiple occasions I've comforted myself with "self, it do…

There do exist people out there that are selfish sexual partners and mis-value sex. It is possible you'll run into someone like this in the real world. But these people are at fault, not you. And I think if you look for sexual partners that display obvious compassion in all aspects of what they do you'll be safe from this kind of behavior.

Re: Post-SSRI sexual dysfunction

#267

Post by jamal-kumar »

bduerst wrote: post #109
jamal-kumar wrote: post #45

SSRIs need to be obsolesced already. Screw the sexual dysfunction, how about increaased risk of suicidal ideation? How about them taking two entire weeks to work? The thing is the rest of the world doesn't seem to feel the burning desire to get as many people on them as possible and even have alternatives which aren't as limited. Reversible MAOI drugs like moclobemide have been around since the 90s and while they hav…

MAOIs have potentially serious dietary interactions and side effects. They can cause serotonin sickness just by taking it with OTC tryptophan supplements. SSRIs are not perfect but have a safer track record of being a first-attack against depression and anxiety, before having to resort to bigger guns like MAOIs.

This is actually the biggest thing keeping this line of treatment from being the preference, but when it comes to reversible vs irreversible MAOIs the dietary interactions are actually not a concern![1] It was actually my first comment when I was told about this, but as it turns out you're more looking at potential drug interactions with the reversible MAOIs. The dietary interactions definitely stand with the irreversible MAOIs in the first generation antidepressants, which I think are generally reserved these days for really serious depression cases that don't respond to other treatment, or parkinsons like symptoms, or people going on jungle treks to drink shaman brews. I think the benefit of treatment kicking in immediately is really key as well, 2 weeks is a long time to wait for a drug to work when you're potentially on the brink of suicide.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188542/

Re: Post-SSRI sexual dysfunction

#268

Post by R0b0t1 »

ironmagma wrote: post #265
R0b0t1 wrote: post #264

Earlier quoted context omitted.

Both irrelevant with medical supervision. SSRIs are highly addictive too; many people never stop taking them.

Overdose is not impossible just because there's a guy in a white suit telling you what to do. People will still take more than they should. > SSRIs aren't addictive [1] There are also a large number of side effects and risks associated with heroin; it's not just constipation as you say. [2] [1] https://www.mayoclinic.org/diseases-conditions/depression/in... . [2] https://www.drugabuse.gov/publications/drugfacts/heroi…

Did you read your 2nd link? All of the typically bad sides in the second grouping are related to poor hygiene and needle sharing. The first grouping is more benign than most antidepressant sides.

Re: Post-SSRI sexual dysfunction

#269

Post by ironmagma »

R0b0t1 wrote: post #268
ironmagma wrote: post #265

Earlier quoted context omitted.

Overdose is not impossible just because there's a guy in a white suit telling you what to do. People will still take more than they should. > SSRIs aren't addictive [1] There are also a large number of side effects and risks associated with heroin; it's not just constipation as you say. [2] [1] https://www.mayoclinic.org/diseases-conditions/depression/in... . [2] https://www.drugabuse.gov/publications/drugfacts/heroi…

Did you read your 2nd link? All of the typically bad sides in the second grouping are related to poor hygiene and needle sharing. The first grouping is more benign than most antidepressant sides.

Yes, I did. Nowhere does it say that. If you want to get a point of reference for what heroin might look like if it wasn't a street drug, oxycodone is quite similar yet distributed without the additives found on the street since it is manufactured by big pharma. Still, it is associated with respiratory depression.

Re: Post-SSRI sexual dysfunction

#270

Post by R0b0t1 »

ironmagma wrote: post #269
R0b0t1 wrote: post #268

Earlier quoted context omitted.

Did you read your 2nd link? All of the typically bad sides in the second grouping are related to poor hygiene and needle sharing. The first grouping is more benign than most antidepressant sides.

Yes, I did. Nowhere does it say that. If you want to get a point of reference for what heroin might look like if it wasn't a street drug, oxycodone is quite similar yet distributed without the additives found on the street since it is manufactured by big pharma. Still, it is associated with respiratory depression.

I know it doesn't say that but it should be obvious most of them are due to poor IV administration. You don't need to administer heroin or morphine via IV.

True, people occasionally OD on prescription medication, but it's usually as a rebound after having the prescription withdrawn and then finding more drugs.

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