Earlier quoted context omitted.
Writing Rust in Dvorak on an EZ Ergo for a living is next-level techno-paradise to many a nerd. Kudos for that! Also, if by any chance you feel like sharing details about how, and in which order you made these transitions; things you wish you knew before trying... please don't hesitate :)
I used Colemak (which is similar to Dvorak) and I would really recommend learning it if you don't already touch type. It does involve a little bit of pain at first and you'll feel really tempted to go back but in a week I was already fast enough to do useful work. I'm not a speed demon by any means, I type at the same speed I did before (60 wpm) except now I don't need to look at the keyboard which is very convenient…
Would it be sensible to make such a 'dramatic' layout change at the same time as the switch to a split ortholinear such as the EZ? It seems more straightforward to do it all at once, but also taking quite the tall order at once — ortho + colemak + strict touch typing.