Android is nearly always a single user system in the sense that TheDong was using. Look at the context a little further down in the guy's comment:
> Like, I'm the only user on my laptop. If you get arbitrary code execution as my user, you can log my keystrokes, steal my passwords and browser sessions, steal my bitcoin wallet, and persist reasonably well.... and once you've stolen my password via say keylogging me typing `sudo`, you now have root too.
In this context, "single user system" means either "single human using the system", or "one human physically sat in front of the system's 'console' at one time". It's in contrast with systems that have multiple human users logged in and using the system simultaneously. So, nearly 100% of "single user systems" of this type will have software running under different "user" accounts on the system, but still meet the definition, because those accounts are actually "machine" or "service" accounts.
I do think that this overload of the terminology is bogus and confusing. It should be called something like "single seat system", but here we are.
> Android security is tight
Yep. That's what I said: "[I]t's my understanding that Android does bother to fairly properly sandbox programs from each other... so an escalation to root would actually be a significant gain in access."