Earlier quoted context omitted.
That's a very apt analogy, as both this and Manhattan are weapons research programs. I'm not very excited in hearing we'll get even more powerful thermo-nuclear bombs.
That isn’t what this would be used for. In fact, yields for the largest deployed H-bombs today I think are smaller than they once were (due to better targeting capabilities).
That's why MIRV was introduced. One ICBM delivering 10 - 20 small warheads result in much greater devastation than an equally heavy warhead in one package, because less power is wasted on air and space.
It's morbid math, but it makes sense.