Earlier quoted context omitted.
Not really; a moonshot is a huge investment to advance the state of the art in something where we know it's possible . It's not a wild shot in the dark. No Saturn V rocket ever failed.
Three men lost their lives in a fire in a capsule.
But unfortunate though that was, it didn't represent a fundamental uncertainty in the achievability of the goal - simply a fatal engineering mistake, which was immediately rectified.