If this work truly is very important, you will read about it from a reputable journal which properly vets this information. This isn't peer reviewed, it's just a website's PDF, there is no way to verify anything put onto this PDF.
I've been very frustrated in my attempts to raise this issue with the local health department where I live. I was brushed aside, and was told "correlation does not imply causation". I doubt that the person on the phone wanted to get into a conversation about dynamical systems or nonlinear data analysis, so I didn't even go there. Instead I sent a letter full of references to published research, and citing other lette…
Tentative paper in the Lancet about it.
Quite why there is so much objection to something that is likely a good thing in any case makes you wonder what the issue is with it.
Thanks for the response. I'm curious what your wife thinks about this article [0], mentioned elsewhere in this discussion. It makes the case that the current RDA for Vitamin D is based on a statistical error, and that the recommended dose should be closer to 8000 IU for young adults. [0] https://pubmed.ncbi.nlm.nih.gov/28768407/
Not OP, but with vitamin D the dosage is actually something you can figure out empirically by testing vitamin D levels and taking supplements. No one who talks about supplementation seems to think a level of 8000 over a long period is necessary to obtain adequate levels. I think by the same token the recommended supplement level of 600 IU is inadequate to reach a sufficient level. But the paper in question didn’t tes…
Correct. It's fairly easy to know whether the dosage you are taking is working, since you can check levels. 8000 units is a really high dose, one that I have never had to give. The article suggests that 98% of people require that much to get to normal levels, which is almost laughable.
This is entirely anecdotal, and I don't have an expert's opinion on this, but I believe I was suffering from Vitamin D toxicity. I had been taking 5000 IU/125 mcg of Vitamin D3 daily for several years, and one day I started experiencing painful and distressing heart palpitations. They persisted on and off for months, until at one point near the beginning of quarantine I ran out of Vitamin D supplements. I went a few…
Fairly likely you are magnesium deficient...magnesium is a critical cofactors to vitamin D and even moderate D3 intake can trigger symptoms such as muscle cramps and heart rhythm changes. Unfortunately no easy way to accurately test a magnesium level, as it’s mostly intracellular and blood tests are pretty much useless
Possible, but I think unlikely. These days, my diet mainly consists of Soylent and Vite Ramen, which together provide me with 105% of my DRV of Magnesium in the form of Magnesium Phosphate and Magnesium Gluconate, respectively.
There are some very vocal people who argue that the risk of toxicity is very low. The studies aren't great. But for most people, taking a moderate dose of Vitamin D will be safe. Unfortunately, I have treated many patients who come to me with high calcium levels due to taking Vitamin D. They do not have parathyroid disease (I have treated thousands of patients with parathyroid disease). They have simply been taking h…
Would you mind telling us what the medical literature says about deaths from Vitamin D overdose? Around how many people in total have died from taking too much Vitamin D?
It is difficult to die of a Vitamin D overdose, though not impossible. Here is what happens: Vitamin D increases calcium absorption from the intestines. Over time, if you are taking too much Vitamin D, your levels can get very very high over time. Vitamin D is fat soluble, so you don't just "pee it out" like some water-soluble vitamins. It stays in you long-term. Eventually your calcium will rise. It can rise slowly, but you will get symptoms. Common symptoms would be fatigue, brain fog, insomnia, headaches, and kidney stones.
If you are at levels where you could potentially die from Vitamin D overdose, your calcium levels will be high enough that you will feel acute symptoms of markedly elevated calcium: like vomiting and confusion. Someone will end up taking you to the hospital, because you will become unconscious. At that point you will be given IV fluids and the calcium will drop. You could die, especially if you have other health issues, but more likely it would be treated and you would get released.
The effects of Vitamin D toxicity are related to the high calcium levels that it causes.
Fairly likely you are magnesium deficient...magnesium is a critical cofactors to vitamin D and even moderate D3 intake can trigger symptoms such as muscle cramps and heart rhythm changes. Unfortunately no easy way to accurately test a magnesium level, as it’s mostly intracellular and blood tests are pretty much useless
Possible, but I think unlikely. These days, my diet mainly consists of Soylent and Vite Ramen, which together provide me with 105% of my DRV of Magnesium in the form of Magnesium Phosphate and Magnesium Gluconate, respectively.
Looking at the nutritional info for Soylent and Vite Ramen shows that they also contain Vitamin D - at the same DRV percentages.
If you're getting 105% of your magnesium from these items, then you're also getting 105% of your Vitamin D before taking any additional Vitamin D supplements/sun exposure.
Adding the 5000IU of Vitamin D3 would be increasing your intake to 5840IU (730% of DRV) - assuming you didn't ingest anything else fortified with Vitamin D.
I've been very frustrated in my attempts to raise this issue with the local health department where I live. I was brushed aside, and was told "correlation does not imply causation". I doubt that the person on the phone wanted to get into a conversation about dynamical systems or nonlinear data analysis, so I didn't even go there. Instead I sent a letter full of references to published research, and citing other lette…
Tentative paper in the Lancet about it. Quite why there is so much objection to something that is likely a good thing in any case makes you wonder what the issue is with it. https://www.thelancet.com/journals/landia/article/PIIS2213-8...
Something to consider when sunlight works and Vit D supplementation does not is how well your digestive tract is absorbing nutrients. Fast, food diaries, observe reactions especially on the skin.
Some of comments show up on the thread but not necessarily on her comment history.
I'm not seeing that. Can you link to an example?
Actually I think I was mistaken. They were more recent comments posted on an older comment by someone else, so they show up further down in her history.