Biohacking Lite

I don't think the advice of not eating fruits is a good one. Nothing wrong with eating an orange every day let's say. The key is to eat things whole. Juice is indeed not recommended,

I agree with most of what you said. Yes sticks are unreliable, but I know my way around food and know how to keep my daily intake of carbs to be And yes, food research is very problematic. Some reasons are valid, for example we will probably never have randomized double blind placebo control study on various food intake patterns which lasts years or decades because it would cost too much and is very hard to do. But we can draw at least some conclusions based on the weight of evidence that we have. My only "problem", setting anecdotes aside, is that people jump on latest trends and make a cult out of it, when there are not even low quality observational studies to support what they claim. For example lately carnivore diet pops up too often with magical claims.

There are differences between people, and some will thrive on some diets where others would be miserable. But that is why we need to find the biggest common ground for all of us first then optimise on differences. Cut all the fluff and pointless optimisations in the beginning, first stick to the most basic things : eat real food, move moderately, sleep well, don't drink alcohol or at least not too often or daily, try to be less reactive (less stressful), do it for a few months and then try to optimise for your ticket in the gene lottery.

The linked-to discussion of insulin has a major error logical error. The title is "Insulin: An Undeserved Bad Reputation", but then the body of the article says for example "Carbs are not alone in being responsible for insulin secretion. Protein can cause just as much, if not more, insulin secretion as carbs". This is a straw man, because the point that is trying to be refused is that "insulin is bad", not "carbs are bad".

Insulin, being necessary for healthy human life, is certainly not "bad". However, a shortage (e.g. Type 1 diabetes) or excess (e.g. Type 2 diabetes) is certainly a problem. Given the current epidemic of Type 2 diabetes, metabolic syndrome, and NAFLD, triggering excess insulin production is certainly something to be wary of.

Also of concern is impinging on the glucagon cycle, and in the linked-to post there is no mention of the important function of glucagon, which is typically considered as having effects opposite to insulin. Maintaining the insulin/glucagon cycle is important in maintenance of a healthy metabolism.

The article makes a point about how "Insulin is not needed for fat storage", but omits the fact that in reality, practically all fat storage is mediated by insulin and its effects on glucose. Insulin mediates glucose transport and promotes absorption of blood glucose into the liver, fat and muscle cells. Once the liver has filled its compliment of glycogen, it will indeed produce fat locally. Non-Alcoholic Fatty Liver Disease (NAFLD) currently afflicts about 25% of the entire human population, and the linked-to author would have the reader believe that excess insulin production isn't an issue? Very strange.

All in all, this article paints a false picture of human metabolism. People eating a typical Western diet should be concerned or at least aware of the facts of that process, and be wary of having an excess or deficit of insulin; and should know that the excess case is the more common condition. A reasonable scientifically-accurate depiction of the process can be found, for example, in Jason Fung's books, "The Diabetes Code" and "The Obesity Code".

> This is a straw man, because the point that is trying to be refused is that "insulin is bad", not "carbs are bad".

I don't see how this is a strawman. Click through to the source article, that bullet point in particular is refuting the common belief that carbs alone are what spike insulin. Most insulin-centric discussion on fitness forums (which is where this was posted) tends to mention insulin spikes in the context of high-GI carbs.

> Also of concern is impinging on the glucagon cycle, and in the linked-to post there is no mention of the important function of glucagon, which is typically considered as having effects opposite to insulin.

Read the linked "part 1". It specifically mentions that newer research shows that glucagon does not counteract insulin as previously thought, and links some studies.

> The article makes a point about how "Insulin is not needed for fat storage", but omits the fact that in reality, practically all fat storage is mediated by insulin and its effects on glucose.

That isn't really relevant to the core point, which is debunking the idea that insulin is what makes us fat.

I just want to restate the fact that the above reddit post is a summary of articles, which themselves are a summary of studies. It is targeted at fitness people who are discussing insulin only in the context of weight loss. There is of course an oversimplification here due to omitting details the target audience might not need as well as being 2 steps removed from the source material.

I mean.... what did you expect... "I CRISPR'd myself and now i'm photosynthetic?"