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Ozempic shows anti-aging effects in trial

trial.medpath.com

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Re: Ozempic shows anti-aging effects in trial

#241

Post by 42772827 »

throwawaylaptop wrote: post #238
42772827 wrote: post #235

Earlier quoted context omitted.

He could have lost all that weight and still had bread, sugar, and potatoes but instead he gave up what he clearly enjoyed. Now he gets to live out the rest of his life fighting cravings, telling himself he's not allowed to enjoy food. How utterly sad.

Believe me, cutting out bread and sugar completely is 10x easier than some kind of lifelong moderation for a person that has struggled for it already for most of his life. And he is extremely happy with his new sugar and bread free life of increased mobility, less pain, and much lower blood pressure. At 64, he's learning how to ride a dirtbike and doing pretty well at it.

The choice is no longer between "cutting out bread and sugar completely" and "some kind of lifelong moderation for a person that has struggled." The choice is now between "cutting out bread and sugar completely" and "removing the struggle to moderate bread and sugar."

You're clearly an advocate for your father making healthy choices. So why would you advocate against the use of a drug that makes that easier?

Re: Ozempic shows anti-aging effects in trial

#242

Post by brcmthrowaway »

Petersipoi wrote: post #82
some_random wrote: post #15

I find it fascinating how much a pretty large group of people just hate semaglutides and seemingly need to believe that it's some kind of Faustian bargain. I'm not talking about the people who are cautious or suspicious, that's more than reasonable, but it's clear that it's not cautious optimism in many.

Just about every single adult woman in my wife's extended family is on Ozempic. None of them are obese at all. Or diabetic. They are all using it to "lose a few pounds" (we're talking like less than 20 pounds; Yes, as you might expect, there are some unrealistic beauty/success standards in my wife's family). So I think there are a lot of people who are annoyed by that, because of the message it sends to completely he…

How does one get Ozempic without being overweight?

Re: Ozempic shows anti-aging effects in trial

#243

Post by danielvaughn »

some_random wrote: post #15

I find it fascinating how much a pretty large group of people just hate semaglutides and seemingly need to believe that it's some kind of Faustian bargain. I'm not talking about the people who are cautious or suspicious, that's more than reasonable, but it's clear that it's not cautious optimism in many.

I’m in the cautiously optimistic camp. I’ve seen two people puke their guts out the day of their doses, but nausea isn’t so bad compared to the health consequences of being overweight.

Re: Ozempic shows anti-aging effects in trial

#245

Post by genewitch »

smt88 wrote: post #152
genewitch wrote: post #113

Earlier quoted context omitted.

> panacea or cure-all specifically, is what i said.

"GLP-1s are beneficial for many conditions downstream of liver dysfunction and metabolic disease" is a much milder claim than "cure-all".

also in the news in the last couple months was "promising for breast cancer" and another cancer (can't remember, don't care), and depression as well as some other mental health disorder.

If you would like to give me money i would be happy to do the research on what claims have been published about GLP-1 inhibitors since they became prescribed off-label.

I assure you it's more than "many conditions downstream of [...]", unless you want to concede that mental health like depression and dementia are related to gut bacteria, then we can be friends.

also, i caught wind that by December 2025 it's going to be recommended / "proven" to work for erectile dysfunction. At a certain point, we're mincing words.

Re: Ozempic shows anti-aging effects in trial

#246

Post by cortesoft »

Aurornis wrote: post #220
cm2187 wrote: post #147

Earlier quoted context omitted.

and there are people who don't get fat no matter what they eat. Not sure what difference it makes to the millions of people I am refering to. Not even sure what is your point.

> and there are people who don't get fat no matter what they eat. This is a myth. When you actually track what these people eat, their daily caloric intake averages out to numbers you'd expect. At best, the difference between "fast metabolism" and "slow metabolism" people in studies comes out to a couple hundred calories per day. You may witness someone consume 2 pizzas and a soda in one sitting without getting fat,…

I think what they mean is "they eat whatever they want and however much they want" and still don't get fat.

Some people just only want to eat an amount that doesn't get them fat. They aren't using any willpower or anything, they just don't want to eat more than a healthy amount for them.

I am not one of those people (I am overweight when I eat as much as I want), but I am for other things. For example, I don't drink very often (only maybe 10 times a year) and don't get very drunk when I do. I just don't feel a desire to drink very often. It takes zero self discipline to not drink for an extended period of time because I don't have the desire for it.

On the other hand, many alcoholics struggle mightily to avoid drinking. It takes all their willpower to not drink.

Everyone is different in their ability to avoid different addictions.

Re: Ozempic shows anti-aging effects in trial

#247

Post by Der_Einzige »

Aurornis wrote: post #222
XorNot wrote: post #160

Earlier quoted context omitted.

With 40% of US adults overweight, that is a substantial plurality though. It's not confirmation bias when it's more then 1 in every 3 people.

> It's not confirmation bias when it's more then 1 in every 3 people If you construct your argument to exclude the 2 out of 3 people who are not overweight and then point out that the remaining 1/3 is overweight, that's the definition of confirmation bias. It's also a disingenuous argument because not all of those 40% are actively trying and failing to modulate their weight in any way. Most people just don't care.

No way that it’s only 40%. Well over half are overweight. Any definition claiming only 40% is lumping in a lot of fatties with the “not overweight”.

Re: Ozempic shows anti-aging effects in trial

#248

Post by cortesoft »

stronglikedan wrote: post #45
noah_buddy wrote: post #20

Earlier quoted context omitted.

Many people (will only speak to America), view being fat as a literal moral failing. Gluttony or overeating are not the sin, but being fat. (From that perspective:)a miracle cure that allows someone to stop being fat is like an indulgence (in the Roman Catholic sense). It’s a cheat, a shortcut that allows the unworthy to reach a state they do not deserve. My opinion is to wait long enough to validate there are no lon…

> Many people (will only speak to America), view being fat as a literal moral failing. Gluttony or overeating are not the sin, but being fat. As an American with a sister with thyroid issues, I can say that is absolutely not true for the majority of Americans. People are mostly sympathetic to those who are not obvious slobs.

> People are mostly sympathetic to those who are not obvious slobs.

Maybe once they hear the story, but most people assume every fat person they see is a slob

Re: Ozempic shows anti-aging effects in trial

#249

Post by Der_Einzige »

brcmthrowaway wrote: post #242
Petersipoi wrote: post #82

Earlier quoted context omitted.

Just about every single adult woman in my wife's extended family is on Ozempic. None of them are obese at all. Or diabetic. They are all using it to "lose a few pounds" (we're talking like less than 20 pounds; Yes, as you might expect, there are some unrealistic beauty/success standards in my wife's family). So I think there are a lot of people who are annoyed by that, because of the message it sends to completely he…

How does one get Ozempic without being overweight?

There’s armies of grey market don’t ask don’t tell e doctors who will give it to you with no request for evidence of being overweight.

Thank god for poor regulation. Unironically thank god and may this situation continue.

Re: Ozempic shows anti-aging effects in trial

#250

Post by unethical_ban »

throwawaylaptop wrote: post #224
op00to wrote: post #202

Earlier quoted context omitted.

[flagged]

I've been on here for 10+ years I think at this point. New throwaway, named throwaway to not even lie, every few months. I tweet with Paul G every now and then positively, because I'm nicer on there. But sorry you dont think I provide value.

It should not be surprising as to why someone would be suspicious in 2025, if someone is insulting anyone who got success from a drug by saying "my dad's dirt worked for him" and then complaining about declining quality on the forums.

Use throwaway identity, pay the price.

I'm glad your dad is healthy and yes, carbs cause issues.

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