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Omicron variant more resistant to vaccine but causes less severe Covid: study

washingtonpost.com

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Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#241
Almost no vaccines prevent infection (e.g., rotavirus vaccine). But most reduce/prevent symptoms. In fact, it's still not proven that existing COVID vaccines 'prevent infection'--that is, provide sterilizing immunity.

Unless I'm missing something, this 'study' seems to do little more than support that understanding.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#242

Earlier quoted context omitted.

This may come off wrong but... COVID is not the first virus. Immunosuppressed people for all of human history have been falling victim to the common cold, the flu and other infections most humans can deal with safely. You can't stop the world economy and the benefit that brings to the majority of society to save a fraction of a percentage point of the population that is Immunocompromised.

How does wearing a mask hurt the economy?

This may be a simple answer to a simple question - but it doesn't.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#243
post #180

Earlier quoted context omitted.

Yes but Spanish Flu was really really bad. Affected everyone. Covid is not the Spanish Flu or even the Flu. The flu kills children and is indiscriminate. 80% of hospitalizations and deaths from Covid are related to weight. We should have prioritized health and Vitamin D in April 2020. At that time it was clear it was mainly affecting overweight people. Of course even almost 2 years later people still don't think that…

And long covid? The two people I know who had longer term side effects were quite healthy. Also by some definitions America is “mostly fat people” so your point is not that meaningful to begin with.

You mean post-viral syndrome? I mean yea it's a thing with viruses but it will go away eventually. I had a cold a few years ago and was sick for like 3 months. Some of long covid is mental, so there's that aspect. Some say vaccination can help but that might just play into the mental aspect.

The human mind can create symptoms very easily, especially if every day you get bombarded by social media and news about Covid.

> Also by some definitions America is “mostly fat people” so your point is not that meaningful to begin with

True, but I'm just saying this wouldn't have been an issue 30 - 50 years ago.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#244
post #21

I have a question for anyone who has a serious level of knowledge on virus evolution: As viruses evolve over time is there any correlation to severity - do they have trade offs as they evolve? I am hoping that it would be some kind of trade off that the virus makes in that it can spread more easily but not be as severe (I understand that it is unlikely nature requires a trade-off). I ask as my concern is that while t…

Not an expert, but from hearing about it from various sources:

As viruses evolve they generally have 2 paths of evolution – they either become more deadly, or more contagious.

The ones that become more deadly will kill the host quicker, and so won't have enough time to spread to others.

The ones that become more contagious are by definition weaker, they will spread to more people, but the effects will be milder.

There are some theories to suggest that pandemics (like the Spanish flu) ended because the virus eventually mutated to a milder, more contagious form.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#245

Earlier quoted context omitted.

I would suspect that most people who are were already vulnerable have already passed or built immunity if the virus is equally dangerous, resulting in a lower than equal death rate despite equivalent risk. Although... Can we never, not even once, be a little optimistic? To me, the news that we may be replacing COVID with a less severe strain is some of the best news of the year. COVID clearly isn't going away at this…

"The omicron variant is cause for concern — but not panic" - Biden "Most Omicron cases in US have been mild but most were vaccinated" from CDC reported on by CNN and MSNBC https://www.cnn.com/2021/12/10/health/omicron-cases-us-cdc/i... https://www.nbcnews.com/health/health-news/cdc-report-omicro... There may be more but that was a quick Google search. You said "politicians and news hosts decided to completely ignore…

It shouldn’t be surprising that the people that complain most vociferously about “The media panic” are selectively hearing only what reinforces their view of the media.

That being said there are a lot of people hand wringing about “we don’t know yet, we don’t know yet” in this very thread. Three weeks into it, and the evidence is almost overwhelming: it is not likely to be nearly as bad.

I followed the original covid news in early January and I fought against the narrative that it was “just the flu”. We would know by now if the news was bad.

That being said, folks should continue to remain vigilant in those areas where spread is prevalent.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#246

Earlier quoted context omitted.

I would suspect that most people who are were already vulnerable have already passed or built immunity if the virus is equally dangerous, resulting in a lower than equal death rate despite equivalent risk. Although... Can we never, not even once, be a little optimistic? To me, the news that we may be replacing COVID with a less severe strain is some of the best news of the year. COVID clearly isn't going away at this…

> Can we never, not even once, be a little optimistic? I'm optimistic. A version of Covid that is much more contagious, but less likely to be severe is a great way to get the immune system of the vaccine avoidant trained on how to recognize and fight Covid. For those who have already been vaccinated, a mild breakthrough infection would serve the same function as a booster shot.

30% less severe with twice the rate of spread does not seem like a good tradeoff. You have an exponential increase in cases but a linear reduction in hospital admissions.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#247

Who cares? If you die with Omicron, you are very old and dying above the average life expectancy, or already sick with chronic preventable illnesses caused by poor lifestyle choices. We should be banning McDonalds advertising, not deputizing waitresses to be vaccination police. If you are not very old or already sick and get omicron, whether you have antibodies or not, you’re going to experience mild symptoms, if any…

You sound like you're fun at parties /s.

If we're looking at the US, "already sick with chronic preventable illnesses causes by poor lifestyle choices" is >50% of our population, so I would say a majority of people care (here). Our society and businesses have done a pretty good job making sure most people don't have the time available to make the right choices.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#248
post #60

Earlier quoted context omitted.

> a little optimistic? Sure, for this immediate wave [more transmissible less virulent] is better than [more transmissible more virulent]. But that's awfully myopic. What happens after that? Since mutation rate is a function of the number of viral particles, and more transmission means many more hosts incubating many more particles, we should expect to see more new variants, faster. So the probability just went up th…

This. When omicron and delta mate and produce offspring, we’re going to be screwed. Deltas virulence + omicron transceptability = the Great Wave of summer 2022. It will be a good year for Pfizer investors and Russia.

When omicron and delta mate and produce offspring

While there can be recombinations of some similar viruses, that's not the common way that viruses propagate, and it's not mating. Point mutations are much more common. And if they do recombine there's no reason to (automatically) expect that the results will be the worst characteristics of both.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#249

This is honesty good news. The best case scenario is a new less deadly highly contagious strain that become the most dominant and spreads worldwide. Way too many comments and articles that try and keep the fear train running full steam. A mild strain of covid that is contagious, leads to natural immunity and doesn’t require a vaccine is an absolute win win for the world.

If I evades vaccines for more dangerous variants, I'm not convinced catching it will make me immune to those variants either. It might actually be different enough to be independent.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#250
post #13

The title is misleading. It is possible that Omicron is just as severe and that the effect in the study is because a large percentage of the population had some immunity from a previous infection or vaccine. > South Africa has a quite high seroprevalence of prior infection, particularly after delta, and in some parts of South Africa up to 80 percent of people were exposed to previous infection. We don’t think it’s a…

I would suspect that most people who are were already vulnerable have already passed or built immunity if the virus is equally dangerous, resulting in a lower than equal death rate despite equivalent risk. Although... Can we never, not even once, be a little optimistic? To me, the news that we may be replacing COVID with a less severe strain is some of the best news of the year. COVID clearly isn't going away at this…

The doctor who found it, isn't a psychic. She doesn't have any information the rest of us don't. She's just describing her personal experience.

And her experience is entirely consistent with Omicron appearing less virulent because it's infecting the previously infected and vaccinated who already have some degree of immunity.

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