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Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

medrxiv.org

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Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#241

Post by QuercusMax »

caleb-allen wrote: post #169
axegon_ wrote: post #127

Earlier quoted context omitted.

Magnesium citrate 200mg(now foods) + animal pak (which includes another 400mg along with a bunch of other vitamins and minerals. I'm a bit over the daily recommendation with those two but most of my spare time revolves around sports since the pandemic so yeah... Differences: - Sleep is considerably better. - Haven't had a single muscle cramp even after something like a 30km walk + 60km bike + gym. Otherwise a common…

I recently started on a 250mg Magnesium Citrate supplement. I began taking it because I have been experiencing weakness in my hands, and after some research reasoned it probably wouldn't hurt to at least try the supplements. I also saw a study that said that 95% of children diagnosed with ADHD are magnesium deficient [0]! Another found a "significant decrease of hyperactivity" in children who were given oral magnesiu…

I just started taking magnesium for my RSI and it has helped a ton. I was also having weird muscle discomfort that stopped me from falling asleep.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#242

Post by vmurthy »

robocat wrote: post #194

It looks like the preprint was published 6 weeks after the study finished (15 April 2020). It is a real shame we can’t get our science moving faster (maybe slow so we don’t break things?).

Perhaps it's the fact that breaking things in science leads to really bad long term effects? Think what would happen if we rushed through a medicine for cancer and it had an effect after a few hundred thousand patients have started taking it.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#243

Post by vmurthy »

jungletime wrote: post #160

One more reason to go for a walk everyday outside for at least 60 minutes.

From the article linked above [0], it appears that 20 minutes is good enough. My GP mentioned something similar to me a couple of weeks ago. The interesting point is _when_ to go out for 20 mins walk and for where I stay (Sydney,Australia), the timing seems to be this :

Noon during winter Before 10 AM or after 3 PM during summer

[0]https://www.myfooddata.com/articles/high-vitamin-D-foods.php

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#244

Post by _ink_ »

PudgePacket wrote: post #90

> Patients were administered oral vitamin D3 1000 IU OD I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.

Could you link them? I got me tested. My vitamin D level is low, but my doctor told me 1.000 IU per day is too much and I should take 1.000 IU only every other day.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#245

Post by goda90 »

bad_user wrote: post #130
goda90 wrote: post #81

Earlier quoted context omitted.

But there is evidence of how deficiencies in these vitamins cause other problems unrelated to coronavirus. If it takes a pandemic to get people to worry about their nutrition, so be it.

> But there is evidence of how deficiencies in these vitamins cause other problems unrelated to coronavirus. To play the devil's advocate, no, that's not true. What we have are just associations which could be spurious. It is often said the general population is deficient in this or that vitamin, but in the west at least we are no longer in danger of developing scurvy or rickets and beyond that there's actually not m…

Actually people still suffer things like scurvy and rickets in developed countries. https://www.independent.co.uk/news/health/victorian-disease-...

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#246

Post by vlovich123 »

valarauko wrote: post #223
vlovich123 wrote: post #144

Earlier quoted context omitted.

Are there really no better studies than just those that categorize "healthy" cohorts & establish standards from that? That would presume a linear causal relation between "health" and vitamin levels in the body which would flip the order of operations - you want to establish a linear causal relation before you start recommending levels.

Well, establishing a linear causal relation isn't always possible, at least not ethically. The recommendations have to balance average dietary intake, tolerable upper limits, and what would constitute an adequate intake that is both necessary and sufficient. For Vitamin C, for example, toxicity is probably in the 2-3 grams range, while just 10 mg/day is sufficient to overcome symptoms of deficiency. So what should th…

Right. I think your arguing my point. The correct way is to understand what the different levels are for each cohort & provide guidance based around your risk factors. We don't know though what that looks like so everyone is stumbling around in the dark. Picking 1 number to recommend nationally/globally is just silly as you point out. Too many factors.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#247

Post by PudgePacket »

_ink_ wrote: post #244
PudgePacket wrote: post #90

> Patients were administered oral vitamin D3 1000 IU OD I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.

Could you link them? I got me tested. My vitamin D level is low, but my doctor told me 1.000 IU per day is too much and I should take 1.000 IU only every other day.

Looks like it was larger than I thought!

https://pubmed.ncbi.nlm.nih.gov/30611908/

> In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe.

https://www.mayoclinicproceedings.org/article/S0025-6196(15)...

> The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D (usually in the range of>50,000-100,000 IU/d for months to years).

You can find more sources by scrolling down to the "summary" section, https://www.foundmyfitness.com/episodes/jre-1474

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#250

Post by valarauko »

vlovich123 wrote: post #246
valarauko wrote: post #223

Earlier quoted context omitted.

Well, establishing a linear causal relation isn't always possible, at least not ethically. The recommendations have to balance average dietary intake, tolerable upper limits, and what would constitute an adequate intake that is both necessary and sufficient. For Vitamin C, for example, toxicity is probably in the 2-3 grams range, while just 10 mg/day is sufficient to overcome symptoms of deficiency. So what should th…

Right. I think your arguing my point. The correct way is to understand what the different levels are for each cohort & provide guidance based around your risk factors. We don't know though what that looks like so everyone is stumbling around in the dark. Picking 1 number to recommend nationally/globally is just silly as you point out. Too many factors.

To be fair, even within the national recommendations, there may be different levels suggested for different groups. There are usually separate numbers suggested for infants, children, teenagers, adult men & women, the elderly, and pregnant/nursing women. The numbers that get tossed around most often are for adult men, but the separate recommendations do exist. The goal of the recommendations is to cover the needs of more than 97% of the group. Your doctor should be able to tweak those recommendations for your individual needs, as required.
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