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The worthlessness of Vitamin D is mildly exaggerated

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Re: The worthlessness of Vitamin D is mildly exaggerated

#231

Earlier quoted context omitted.

More hours of sun, but it's less intense.

Is it really less intense? When I go out on a sunny day in Denmark it is murder. When I go out on a sunny day in Italy it's generally just overall warm. At any rate another factor is that in the Northern regions it's my experience people do their best to soak up as much sun as possible.

Sit in the sun for a bit closer to the equator. You'll feel it very quickly

Re: The worthlessness of Vitamin D is mildly exaggerated

#232
post #7

This is a refreshingly balanced and honest analysis of Vitamin D studies. The strongest evidence for Vitamin D is in people who are severely deficient. Bumping up to a normal range can provide some improvements. The health influencers started noticing that the Vitamin D studies coming out weren't matching their original hype for Vitamin D, so many pivoted to trying to make claims that most people are severely deficie…

My family runs a blood analysis lab in Belgium for which I wrote some of the statistics gathering software. The thresholds for 25-OH vitamin D: When I looked at all 1738 blood samples that had their Vitamin D tested between Feb 1, 2020 and Mar 13, 2020 (We were looking into the link between Vitamin D and COVID-19): The median (P50) was 20.1 ng/mL and the average was 22.4 ng/mL. Standard deviation: 11.24 ng/mL Half th…

What do you think about the thresholds themselves? How often are they updated usually with new research?

Re: The worthlessness of Vitamin D is mildly exaggerated

#233

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

My life changed after I got tested for vit D and started talking supplements. I was severely deficient. I am now sufficient and everything changed for me.

2 years ago i caught some repeated strep throat infection, repeated like 6-8 times - because my original general doctor said that with low CRP there is no way i have bacterial infection... before i found a doctor who finally did proper swab and ABTs - but i was so far gone that i got horrible headaches, muscle pain, stinging, absolute weakness... on top of that i cought covid and proper flu. Totally crazy, when they did mi vitamin D it was at 10% of minila recomended value. I god vit D and some immunity pills(pigs blood cells - this is questionable). I was slurping the vitamin D every day and in couple of weeks I was almost back to normal.

I have seen neurologists, imunologist, infection diseases specialist, everything is boreliosis qack and even somatic doctor...

Funny thing is before i got sick i spent 3 months on tenerife, so no reason for me to have low vit D. But it was probably depleted by immunity trying to fight the repeated infections.

so yeah, get your vitamin D checked if you feel weak, low on mood or anything out of zen

Re: The worthlessness of Vitamin D is mildly exaggerated

#234

I have made this comment on HN many times [0] now but: it's the goddamn sunlight. Sunlight has many pathways in the body, and increased vitamin D levels are just one of those pathways. Swallowing one element of a many-element pathway cannot simulate the human synthesis of vitamin D! This should be obvious! Your car might not run because of bad needle bearings, but the solution is not to add them to the gas tank! Firs…

Which could be one of the reason people near the Mediterranean sea (for example in Italy) and tennis players do tend to live longer than average. Now of course there s probably more than one reason but those sure do enjoy time outside.

Re: The worthlessness of Vitamin D is mildly exaggerated

#235

Earlier quoted context omitted.

Is it really less intense? When I go out on a sunny day in Denmark it is murder. When I go out on a sunny day in Italy it's generally just overall warm. At any rate another factor is that in the Northern regions it's my experience people do their best to soak up as much sun as possible.

The sun is at a lower angle from the horizon at higher latitudes. It passes through more atmosphere, losing some UV, and also the surface irradiance on the ground (energy per unit land area) is lower.

This. What I've learned for VitD conversion in the skin the sun needs to be more than 45° "high". Below that it's not much effective.

Those long summer evenings in northern Europe are thus not all that useful for VitD.

Re: The worthlessness of Vitamin D is mildly exaggerated

#238
post #7

This is a refreshingly balanced and honest analysis of Vitamin D studies. The strongest evidence for Vitamin D is in people who are severely deficient. Bumping up to a normal range can provide some improvements. The health influencers started noticing that the Vitamin D studies coming out weren't matching their original hype for Vitamin D, so many pivoted to trying to make claims that most people are severely deficie…

My family runs a blood analysis lab in Belgium for which I wrote some of the statistics gathering software. The thresholds for 25-OH vitamin D: When I looked at all 1738 blood samples that had their Vitamin D tested between Feb 1, 2020 and Mar 13, 2020 (We were looking into the link between Vitamin D and COVID-19): The median (P50) was 20.1 ng/mL and the average was 22.4 ng/mL. Standard deviation: 11.24 ng/mL Half th…

The curve on your diagram makes me think that you've fitted a normal (Gaussian) curve to the data. By eye, the distribution looks a bit more like log-normal, and so if you're still working on the data, you might want to try that to see. Not that anything you've said or concluded seems wrong, though.

Re: The worthlessness of Vitamin D is mildly exaggerated

#239

Earlier quoted context omitted.

My family runs a blood analysis lab in Belgium for which I wrote some of the statistics gathering software. The thresholds for 25-OH vitamin D: When I looked at all 1738 blood samples that had their Vitamin D tested between Feb 1, 2020 and Mar 13, 2020 (We were looking into the link between Vitamin D and COVID-19): The median (P50) was 20.1 ng/mL and the average was 22.4 ng/mL. Standard deviation: 11.24 ng/mL Half th…

The curve on your diagram makes me think that you've fitted a normal (Gaussian) curve to the data. By eye, the distribution looks a bit more like log-normal, and so if you're still working on the data, you might want to try that to see. Not that anything you've said or concluded seems wrong, though.

The normal curve in the image is there for operators to visually check if the machine results are normal distributed or not. It's a "stencil", not data.

The software actually does a Lilliefors normality test which returns a big No on this data.

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