Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Psilocybin desynchronizes the human brain

nature.com

Post reply on HN
Print view View original

231–240 of 276 posts

Re: Psilocybin desynchronizes the human brain

#231

Post by greentxt »

foobiekr wrote: post #129
__MatrixMan__ wrote: post #110

Earlier quoted context omitted.

Anecdotal, but I've tripped with two people who showed seizure like symptoms that they never had before or since. Couldn't find any data at the time. Tried to get them to submit experience reports on erowid so that there would be some data out there, but they didn't want to put anything about it in writing.

Are you sure shrooms? If chocolates or gummies the compound therein is not quite the same as recent news stories have noted.

Can I get a cite on one of those news stories?

Re: Psilocybin desynchronizes the human brain

#232

Post by newzisforsukas »

latexr wrote: post #192
newzisforsukas wrote: post #152

Earlier quoted context omitted.

> Men who owned handguns were eight times more likely than men who didn’t to die of self-inflicted gunshot wounds. > Women who owned handguns were more than 35 times more likely than women who didn't to kill themselves with a gun. That is specific to handguns and kind of what would be expected? Also, being more likely than not likely at all is pretty much comparing degrees of impossibility. Seems like this pops up in…

> That is specific to handguns So what? More likely than not that’s the type of gun the person we’re discussing used. > and kind of what would be expected? Again, what’s your point? Because it’s expected we shouldn’t discuss it or do anything about it? Let’s bring back lead paint while we’re at it; I mean, it’s expected that it causes brain damage. > "We need to stop this bad thing that rarely happens! Only when it h…

> Again, what’s your point?

The article states specifically that people who commit suicide with a gun are more likely to do so if they own a handgun. IMO, that follows from the mechanics of the scenario.

It is easier to point a handgun at yourself and pull the trigger than it is to do so with a long gun. So, IMO, it is common sense that it is more likely that someone committing suicide by firearm chooses to do so with a handgun over a long gun, and they are more likely to do that if they own a handgun already.

However, it isn't like a random person who owns a gun is significantly more likely to complete a suicide attempt just because they own a gun. Yet, a person who is already at risk of suicide might have an increased risk if they own guns.

That being said, as a random individual, the risk of completed suicide over a lifetime is incredibly low, and that risk is even lower for suicide by any firearm.

> Let’s bring back lead paint while we’re at it; I mean, it’s expected that it causes brain damage.

I don't see this as being analogous to what I am saying. Maybe I am missing something.

Re: Psilocybin desynchronizes the human brain

#233

Post by newzisforsukas »

luqtas wrote: post #194
newzisforsukas wrote: post #152

Earlier quoted context omitted.

> Men who owned handguns were eight times more likely than men who didn’t to die of self-inflicted gunshot wounds. > Women who owned handguns were more than 35 times more likely than women who didn't to kill themselves with a gun. That is specific to handguns and kind of what would be expected? Also, being more likely than not likely at all is pretty much comparing degrees of impossibility. Seems like this pops up in…

barely happens but suicides rates among teens are increasing & never were this high [0] students who take a weapon with them to school, impact welfare & performance of nearby students just because they are aware of that [1] [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414751/ [1] https://apadiv15.org/wp-content/uploads/2019/02/Reducing-Wea... go figure the plot you have to live after an event of this type

> go figure the plot you have to live after an event of this type

I am not saying these aren't issues, but that the risk is often overstated.

Also, I think there are plenty of other things that are greater risks than the likelihood of gun violence toward oneself or others that impact lifetime well-being for individuals on a socioeconomic scale, especially in schools.

Re: Psilocybin desynchronizes the human brain

#234

Post by dleary »

ikekkdcjkfke wrote: post #228
ipaddr wrote: post #203

Earlier quoted context omitted.

Psychedelics weaken your emotional associations. Which can be helpful and/or unhelpful. It's not a matter of more work. Whatever feeling you had about this chair has changed. It use to represent a memory or a feeling from childhood. That's changed or is gone for better or worse. That's how to perceive how it works. If you are 'fucked' because you can't move on it will help. If you feel a lack of connections to things…

These negative emotions helped us survive before, but in this artificial world there needs to be artificial solutions

In the past, a lot fewer people lived until they were “old”.

So, the deleterious effects of trauma emotions “mattered less”. If you can never sleep through the night without waking up screaming, that is a bad effect. But if you only have a year or two of lifespan left, then you experience less “penalty” than if you had lots of years left.

Now, we ship boys off to war at 18, or even younger. They get PTSD in war, and then live 50+ years afterwards with the bad effects.

Re: Psilocybin desynchronizes the human brain

#235

Post by bitcoin_anon »

tambourine_man wrote: post #208
ipaddr wrote: post #204

Earlier quoted context omitted.

[flagged]

The amount of antivax shit that floats around in a supposedly well informed community such as this is nauseating. Makes me lose my faith in humanity a bit every time I read it.

Remember when the authorities pulled the JnJ vaccine due to adverse events after it was administered to millions of people? It seems some caution was warranted, no?

Re: Psilocybin desynchronizes the human brain

#236

Post by coffeebeqn »

trompetenaccoun wrote: post #201
RamblingCTO wrote: post #181

Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…

You're right. There are a lot of misconceptions because the majority of people has never tried strong psychedelic drugs like psilocybin or LSD, so their information is based entirely on hearsay. Both in the negative sense ("you can permanently 'fry' your brain", "you'll jump out of the window", etc), as well as positive myths like that it's going to solve all your mental issues. I'm not fully sure regarding the last…

If you have mental health issues and you try to self medicate with psychedelics just know you’re playing with fire. I’ve had one positive-ish and three negative-ish ones myself. I get a lot of anxiety and mania for some reason on the second half which tends to make me kind of spiral and there’s sometimes not much to grab onto when you’re deep in it. If you really must do it alone , having something like a benzo on hand can help if things go off the rails.

Re: Psilocybin desynchronizes the human brain

#237

Post by raincom »

progmetaldev wrote: post #92
lamp_book wrote: post #87

Earlier quoted context omitted.

Sounds like it could be mild dissociation/depersonalization. It's not typically considered a primary effect of psilocybin, but there is a small mention here on classical psychedelics: https://en.wikipedia.org/wiki/Dissociative

I was already predisposed to anxiety, but after using LSD quite a bit in my teens, my anxiety took over my waking life. During high anxiety and panic attacks, I often experience dissociation/depersonalization effects. I feel like I am disconnected from myself, and watching what is happening, like in a dream. The only thing I really connect with is the anxiety and fear. Over the years, through therapy and medication,…

It is very interesting to note that the same depersonalization is experienced after a long, deep meditative practice. I realized that this meditative depersonalization was same as when I was really mad.

Re: Psilocybin desynchronizes the human brain

#238

Post by throwaway3306a »

tambourine_man wrote: post #206
muzani wrote: post #174

Earlier quoted context omitted.

Thankfully in this country, we don't revoke licenses for telling people to submit health data.

I don’t know or care which country you’re in, but advising patients against vaccines is a license-losing offense in most of the civilized world. And that’s only the mildest of consequences, you’d be facing criminal charges as well in most countries.

[flagged]

Re: Psilocybin desynchronizes the human brain

#239

Post by sowut »

antegamisou wrote: post #145
sowut wrote: post #2

incredibly powerful drug. we should be training a legion of mystics using psilocybin instead of criminalizing it and obfuscating the implications of its use

You're like 70 years late https://en.wikipedia.org/wiki/MKUltra Project MKUltra was an illegal human experiments program designed and undertaken by the U.S. Central Intelligence Agency (CIA) to develop procedures and identify drugs that could be used during interrogations to weaken people and force confessions through brainwashing and psychological torture. [...] The project studied the effects of psychoactive drugs,…

except that was a secret government program and humans were used as guinea pigs. that's not what i'm talking about at all

Re: Psilocybin desynchronizes the human brain

#240

Post by stvltvs »

mistermann wrote: post #135
stvltvs wrote: post #23

Earlier quoted context omitted.

It might clarify things to say unconscious beliefs, expectations, or thought patterns instead of knowledge. It doesn't seem that the subconscious mind is a font of pure wisdom and knowledge but it powerfully affects us in ways that our conscious mind isn't aware of, by definition. Before using psychedelics, it's important to anchor ourselves by questioning the difference between knowing something and feeling like we…

> Before using psychedelics, it's important to anchor ourselves by questioning the difference between knowing something and feeling like we know something. The inverse seems more prudent to me, since mostly all global decisions get made when not on psychedelics, and we arguably have a severe lack of truly novel, out of the box ideas...who knows, maybe something useful for addressing climate change, polarization, etc…

Idea generation from psychedelics is okay, but we should avoid thinking we've received a divine revelation of unquestionable truth because it felt true.
Post reply on HN